| Rifamycin | An antibacterial used to treat traveler's diarrhea. |
| Vitamin A | A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. |
| Vidarabine | An antiviral agent used to treat various viral infections. |
| Betaxolol | A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). |
| Moxifloxacin | A fluoroquinolone antibiotic used to treat various bacterial infections. |
| Medrysone | A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions. |
| Dapiprazole | Used in the treatment of iatrogenically induced mydriasis produced by adrenergic (phenylephrine) or parasympatholytic (tropicamide) agents used in certain eye examinations. |
| Fluorometholone | An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye. |
| Carbamoylcholine | A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. |
| Trifluridine | A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers. |
| Chloramphenicol | A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. |
| Dipivefrin | A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma. |
| Framycetin | An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. |
| Verteporfin | A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration. |
| Ketorolac | An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches. |
| Sulfamethizole | A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. |
| Diclofenac | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| Latanoprost | An isopropyl ester prodrug used to treat increased intraocular pressure. |
| Flumethasone | A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions. |
| Fluorescein | A dye used in angiography or angioscopy of the iris and retina. |
| Methazolamide | A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. |
| Flurbiprofen | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| Epinastine | An H1 receptor antagonist used to prevent itching in allergic conjunctivitis. |
| Acyclovir | A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. |
| Proparacaine | A topical anesthetic used for ophthalmic practice. |
| Tropicamide | A muscarinic receptor antagonist used to dilate the pupil. |
| Acetazolamide | A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. |
| Natamycin | A macrolide antifungal used to treat fungal infections of the eye. |
| Dorzolamide | A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. |
| Rimexolone | A glucocorticoid used to treat inflammation of the eye. |
| Bimatoprost | A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. |
| Cocaine | An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. |
| Oxymetazoline | An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. |
| Demecarium | For the topical treatment of chronic open-angle glaucoma. |
| Bromfenac | An NSAID used to treat postoperative pain and inflammation of the eye. |
| Apraclonidine | An alpha adrenergic agonist used to treat raised intraocular pressure. |
| Lomefloxacin | A fluoroquinolone used to prevent and treat a wide variety of infections in the body. |
| Cyclopentolate | An anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing. |
| Neomycin | An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. |
| Ganciclovir | A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. |
| Benzylpenicillin | A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. |
| Echothiophate | An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma. |
| Emedastine | A selective H1-receptor antagonist used topically to manage symptoms of allergic conjunctivitis. |
| Levocabastine | A selective histamine H1 receptor antagonist indicated for the management of seasonal allergic conjunctivitis symptoms. |
| Guanethidine | An antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension. |
| Kanamycin | An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. |
| Brinzolamide | A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Levobunolol | A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Metipranolol | A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Ranibizumab | A recombinant humanized monoclonal antibody and VEGF-A antagonist used for the management of macular edema after retinal vein occlusion, age-related macular degeneration (wet), and diabetic macular edema. |
| Ephedrine | An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. |
| Antipyrine | An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. |
| Fusidic acid | A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. |
| Acetylcholine | A parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. |
| Clioquinol | An antifungal cream used to treat a variety of fungal infections. |
| Pegaptanib | A selective vascular endothelial growth factor (VEGF) antagonist used for the treatment of neovascular (wet) age-related macular degeneration. |
| Xylometazoline | A direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. |
| Potassium Iodide | An oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency. |
| Fomivirsen | Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428]. |
| Alcaftadine | A H1 histamine receptor antagonist for ophthalmic use to prevent itching associated with allergic conjunctivitis. |
| Besifloxacin | A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis. |
| Lodoxamide | An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. |
| Nepafenac | An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. |
| Povidone-iodine | A topical antiseptic agent used for the treatment and prevention of infection in wounds. |
| Unoprostone | A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. |
| Tafluprost | An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Spaglumic Acid | Used in patients with allergic conjunctivitis. |
| Aflibercept | A vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy. |
| Ocriplasmin | A proteolytic enzyme used to treat symptomatic vitreomacular adhesion by dissolving the protein matrix responsible for the adhesion between the vitreous and macula. |
| Befunolol | Used in the management of open angle glaucoma. PMID: 12480285. |
| Synephrine | Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... |
| Dexpanthenol | An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). |
| Hypromellose | An ingredient used in a wide variety of medications, and is not an approved medication. |
| Hydrogen peroxide | A compound used as a disinfectant and sterilizer. |
| Homatropine | An anticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough. |
| Rose bengal | Indicated as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected, and as an aid in the diagnosis of keratoconjunctivitis sicca, keratitis,... |
| Boric acid | No FDA- or EMA-approved therapeutic indications on its own. |
| Dihydrostreptomycin | Dihydrostreptomycin is an antibiotic. |
| Anecortave | Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension). |
| Clobetasone | A corticosteroid used to treat dry eyes, eczema, and dermatitis. |
| Sulfadicramide | Not Annotated |
| Aceclidine | Aceclidine has been marketed in Europe but has not been used clinically in the United States. It is used in the treatment of open-angle glaucoma and is a parasympathomimetic agent. |
| Micronomicin | Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina. |
| Azidamfenicol | Not Annotated |
| Ibopamine | Not Annotated |
| Guaiazulen | Not Annotated |
| Edetate sodium | Not Annotated |
| Paraoxon | Not Annotated |
| Bendazac | Prior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the... |
| Tyrothricin | A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections. |
| Pranoprofen | Not Annotated |
| Dibrompropamidine | Not Annotated |
| Picloxydine | Not Annotated |
| Formocortal | Not Annotated |
| Aluminium acetotartrate | Not Annotated |
| Bibrocathol | Not Annotated |
| Alteplase | A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. |
| Ascorbic acid | A vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron. |
| Alclometasone | A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses. |
| Idoxuridine | A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. |
| Sulfisoxazole | A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. |
| Indomethacin | A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. |
| Nitrofural | For the treatment of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms. |
| Phenylephrine | An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. |
| Ampicillin | A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. |
| Famciclovir | A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster. |
| Brimonidine | An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea. |
| Carteolol | A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. |
| Cinchocaine | An anesthetic used for local or regional anesthesia. |
| Ciprofloxacin | A second generation fluoroquinolone used to treat various susceptible bacterial infections. |
| Piroxicam | An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. |
| Atropine | A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. |
| Clonidine | An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. |
| Oxytetracycline | A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. |
| Triamcinolone | A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. |
| Sulfacetamide | A corticosteroid used to treat inflammatory ocular conditions and acne vulgaris. |
| Tobramycin | An aminoglycoside antibiotic used to treat cystic fibrosis, lung infections, eye infections, and a variety of other infections. |
| Nedocromil | A pyrano quinoline used to treat allergic conjunctivitis. |
| Procaine | A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. |
| Hydrocortisone | A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. |
| Scopolamine | A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). |
| Tetracycline | An antibiotic used to treat a wide variety of susceptible infections. |
| Olopatadine | A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. |
| Gentamicin | An aminoglycoside used to treat a wide variety of infections in the body. |
| Cysteamine | A cystine depleting agent used to treat the effects of cystinosis. |
| Prednisolone | A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. |
| Sirolimus | An immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. |
| Oxybuprocaine | A local anesthetic used in ophthalmology. |
| Ketotifen | A histamine H1 receptor blocker used to treat mild asthma and allergic conjunctivitis. |
| Salicylic acid | An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. |
| Netilmicin | An aminoglycoside used to treat a wide variety of infections in the body. |
| Methylprednisolone | A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. |
| Azelastine | A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. |
| Physostigmine | A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity. |
| Cromoglicic acid | A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. |
| Gatifloxacin | A fourth generation fluoroquinolone used to treat a wide variety of infections in the body. |
| Norfloxacin | A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine. |
| Pilocarpine | A muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. |
| Heparin | An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation. |
| Miconazole | An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. |
| Cefuroxime | A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. |
| Levofloxacin | A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. |
| Diclofenamide | A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. |
| Ofloxacin | An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. |
| Dexamethasone | A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. |
| Desonide | A topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. |
| Neostigmine | A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. |
| Ethylmorphine | Ethylmorphine is an analgesic used for pain relief. |
| Acetic acid | An antimicrobial agent used to treat susceptible infections of the external auditory canal. |
| Oxyphenbutazone | A nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. |
| Inosine | A nutritional supplement touted to improve athletic performance and a drug used in vitro as a red blood cell rejuvenator for a unit of red blood cells that will be used in a clinical setting. |
| Acetylcysteine | A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. |
| Naphazoline | A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. |
| Sulfaphenazole | For the treatment bacterial infections. |
| Tetryzoline | An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations. |
| Hyaluronic acid | Used to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical... |
| Fluocortolone | Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders. |
| Tetracaine | A local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. |
| Chlortetracycline | The first tetracycline antibiotic most commonly used for veterinary purposes. |
| Chymotrypsin | No therapeutic indications. |
| Resorcinol | Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L2727, F61] or as topical antibacterial skin... |
| Methscopolamine | Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... |
| Nandrolone | Nandrolone, also known as 19-nortestosterone or 19-norandrostenolone, is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. |
| Propamidine | Not Annotated |
| Sodium borate | No FDA- or EMA-approved therapeutic indications on its own. |
| Loteprednol | Not Annotated |
| Propanoic acid | An antimicrobial food additive. |
| Hexamidine | Not Available |
| Riboflavin | A vitamin used to correct vitamin B2 deficiency. |
| Lifitegrast | A medication used to treat dry eye disease. |
| Cenegermin | A recombinant human nerve growth factor used to treat neurotrophic keratitis. |
| Netarsudil | A rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension. |
| Polymyxin B | A polymyxin antibiotic used to treat a wide variety of infections in the body. |
| Cortisone | A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to... |
| Chlorhexidine | An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis. |
| Vancomycin | A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. |
| Latanoprostene bunod | A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. |
| Voretigene neparvovec | An adeno-associated viral gene therapy used to treat biallelic RPE65 mutation associated retinal dystrophy. |
| Brolucizumab | An anti VEGF-A monoclonal antibody indicated to treat neovascular age related macular degeneration. |
| Chloroprednisone | Not Annotated |