Hydrazines

All categories

Name: Hydrazines
Accession Number: DBCAT000469
Description: Substituted derivatives of hydrazine (formula H2N-NH2).
Drugs: Drug Drug Description
Aconiazide Not Annotated
Aldoxorubicin Investigated for use/treatment in solid tumors.
Apilimod Investigated for use/treatment in crohn's disease and psoriasis and psoriatic disorders.
Balsalazide An aminosalicylate used to treat ulcerative colitis.
Benserazide A medication used to treat Parkinson's disease, parkinsonism, and restless leg syndrome.
Carbidopa A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
Dynasore Not Annotated
Hetrombopag Hetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).
Iproniazid For the treatment of depression (originally intended to treat tuberculosis).
Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
Levosimendan A calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure.
Meldonium Not Annotated
Methaniazide Methaniazide is a small molecule drug. Methaniazide has a monoisotopic molecular weight of 231.03 Da.
Opiniazide Opiniazide is a small molecule drug. Opiniazide has a monoisotopic molecular weight of 329.1 Da.
Phenelzine A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
PIK-75 PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Salinazid Salinazid is a small molecule drug. Salinazid has a monoisotopic molecular weight of 241.09 Da.
Semapimod Semapimod has been used in trials studying the treatment of Crohn Disease.
Simendan Not Annotated
Sivifene Investigated for use/treatment in cervical dysplasia/cancer, genital warts, and skin cancer.
Todralazine Todralazine is a small molecule drug. Todralazine has a monoisotopic molecular weight of 232.1 Da.
VP-14637 MDT-637 has been investigated for the treatment of Drug Safety.
Drugs & Drug Targets: Drug Target Type
Aldoxorubicin DNA topoisomerase 2-beta target
Aldoxorubicin DNA topoisomerase 2-alpha target
Apilimod 1-phosphatidylinositol 3-phosphate 5-kinase target
Apilimod Interleukin-12 subunit alpha target
Balsalazide Human Cyclooxygenases target
Balsalazide NADPH azoreductase enzyme
Balsalazide Peroxisome proliferator-activated receptor gamma target
Balsalazide Polyunsaturated fatty acid 5-lipoxygenase target
Balsalazide Prostaglandin G/H synthase 2 target
Balsalazide Prostaglandin G/H synthase 1 target
Benserazide Aromatic-L-amino-acid decarboxylase target
Carbidopa Aromatic-L-amino-acid decarboxylase target
Dynasore TIR domain-containing adapter molecule 1 target
Dynasore Dynamin-1-like protein target
Dynasore Dynamin-2 target
Dynasore Dynamin-1 target
Hetrombopag Thrombopoietin receptor target
Iproniazid Cytochrome P450 2C9 enzyme
Iproniazid Amine oxidase [flavin-containing] B enzyme
Iproniazid Cytochrome P450 2D6 enzyme
Iproniazid Amine oxidase [flavin-containing] A enzyme
Iproniazid Amine oxidase [flavin-containing] A target
Iproniazid Amine oxidase [flavin-containing] B target
Iproniazid Monoamine oxidase target
Isoniazid Catalase-peroxidase target
Isoniazid Enoyl-[acyl-carrier-protein] reductase [NADH] target
Isoniazid Cytochrome P450 2E1 enzyme
Isoniazid Cytochrome P450 1A2 enzyme
Isoniazid Cytochrome P450 2C9 enzyme
Isoniazid Cytochrome P450 2D6 enzyme
Isoniazid Cytochrome P450 2C19 enzyme
Isoniazid Arylamine N-acetyltransferase 2 enzyme
Isoniazid Arylamine N-acetyltransferase enzyme
Isoniazid Cytochrome P450 2A6 enzyme
Isoniazid Cytochrome P450 2C8 enzyme
Isoniazid Dihydrofolate reductase target
Isoniazid Albumin carrier
Isoniazid Cytochrome P450 3A4 enzyme
Levosimendan cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A target
Levosimendan Troponin C, slow skeletal and cardiac muscles target
Levosimendan ATP-sensitive inward rectifier potassium channel 11 target
Levosimendan ATP-sensitive inward rectifier potassium channel 8 target
Levosimendan Phosphodiesterase 3 target
Meldonium ATP-dependent 6-phosphofructokinase, platelet type target
Meldonium Organic cation/carnitine transporter 2 target
Meldonium Gamma-butyrobetaine dioxygenase enzyme
Meldonium Gamma-butyrobetaine dioxygenase target
Phenelzine Cytochrome P450 3A5 enzyme
Phenelzine Cytochrome P450 3A4 enzyme
Phenelzine Cytochrome P450 2C8 enzyme
Phenelzine Cytochrome P450 2C19 enzyme
Phenelzine Alanine aminotransferase 2 target
Phenelzine Alanine aminotransferase 1 target
Phenelzine Glutamate decarboxylase 2 target
Phenelzine 4-aminobutyrate aminotransferase, mitochondrial target
Phenelzine Cytochrome P450 2E1 enzyme
Phenelzine Cytochrome P450 3A7 enzyme
Phenelzine Monoamine oxidase target
Phenelzine Cytochrome P450 2D6 enzyme
Phenelzine Cytochrome P450 3A Subfamily enzyme
Phenelzine Amine oxidase [flavin-containing] B enzyme
Phenelzine Amine oxidase [flavin-containing] A enzyme
Phenelzine Amine oxidase [flavin-containing] A target
Phenelzine Amine oxidase [flavin-containing] B target
Phenelzine Amine oxidase [copper-containing] 3 target
PIK-75 DNA-dependent protein kinase catalytic subunit target
PIK-75 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform target
PIK-75 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform target
Semapimod RAF proto-oncogene serine/threonine-protein kinase target
Semapimod Mitogen-activated protein kinase 14 target
VP-14637 Fusion glycoprotein F0 target

Drug	Drug Description
Aconiazide	Not Annotated
Aldoxorubicin	Investigated for use/treatment in solid tumors.
Apilimod	Investigated for use/treatment in crohn's disease and psoriasis and psoriatic disorders.
Balsalazide	An aminosalicylate used to treat ulcerative colitis.
Benserazide	A medication used to treat Parkinson's disease, parkinsonism, and restless leg syndrome.
Carbidopa	A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
Dynasore	Not Annotated
Hetrombopag	Hetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).
Iproniazid	For the treatment of depression (originally intended to treat tuberculosis).
Isoniazid	An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
Levosimendan	A calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure.
Meldonium	Not Annotated
Methaniazide	Methaniazide is a small molecule drug. Methaniazide has a monoisotopic molecular weight of 231.03 Da.
Opiniazide	Opiniazide is a small molecule drug. Opiniazide has a monoisotopic molecular weight of 329.1 Da.
Phenelzine	A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
PIK-75	PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Salinazid	Salinazid is a small molecule drug. Salinazid has a monoisotopic molecular weight of 241.09 Da.
Semapimod	Semapimod has been used in trials studying the treatment of Crohn Disease.
Simendan	Not Annotated
Sivifene	Investigated for use/treatment in cervical dysplasia/cancer, genital warts, and skin cancer.
Todralazine	Todralazine is a small molecule drug. Todralazine has a monoisotopic molecular weight of 232.1 Da.
VP-14637	MDT-637 has been investigated for the treatment of Drug Safety.

Hydrazines

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