Hormone Antagonists

Hormone Antagonists
Accession Number

Chemical substances which inhibit the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.

DrugDrug Description
AbarelixFor palliative treatment of advanced prostate cancer.
FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
AminoglutethimideAn adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
SpironolactoneAn aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism.
MontelukastA leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
RaloxifeneA selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women.
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
ToremifeneA first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
NilutamideAn antineoplastic hormone used to treat prostate cancer.
TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
EplerenoneAn aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
ExemestaneAn aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
BromocriptineA dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
DrospirenoneA progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
Cyproterone acetateA steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
LintitriptFor the treatment of pancreatic cancer and appetite disorders.
AbirateroneAn antiandrogen used in the treatment of metastatic castration-resistant prostate cancer and metastatic high-risk castration-sensitive prostate cancer.
GanirelixA GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges.
FormestaneFor the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Canrenoic acidAn aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels.
TiboloneFor the relief of post-menopausal symptoms and for the prevention of osteoporosis .
CanrenoneAn antimineralocorticoid and active metabolite of spironolactone used in the treatment of primary hyperaldosteronism and edematous states caused by secondary hyperaldosteronism (e.g. heart failure).
OnapristoneOnapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of...
ChlormadinoneA progestin indicated in combination with an estrogen for oral combined hormonal contraceptive therapy.
RelcovaptanNot Annotated
TeverelixInvestigated for use/treatment in benign prostatic hyperplasia, endometriosis, and prostate cancer.
AcylineAcyline has been investigated for the prevention and treatment of Hypogonadism and Contraception.
Chlormadinone acetateA progestin indicated in combination with an estrogen for birth control.
RelugolixAn oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.
CetrorelixA synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy.
MifepristoneA cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.
AtosibanAn inhibitor of oxytocin and vasopressin used to delay imminent preterm birth in pregnant adult women displaying specific clinical observations.
DienogestAn oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
LiarozoleLiarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
CarbimazoleA drug used for the reduction of thyroid function.
ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
PropylthiouracilA thiourea antithyroid agent used to treat hyperthyroidism.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
ClomifeneA medication used to induce ovulation.
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
DanazolA synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts.
PranlukastA leukotriene receptor antagonist for the treatment of allergic rhinitis and asthma symptoms.
NaringeninNot Available
ICI-164384Not Available
AfimoxifeneFor the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring.
BazedoxifeneA selective estrogen receptor modulator (SERM) used to treat moderate to severe vasomotor symptoms in menopause and osteoporosis alone or in combination with conjugated estrogens.
EnclomipheneNot Annotated
SeratrodastSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Hydroxyprogesterone caproateA synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
WortmanninWortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
MoxestrolNot Annotated
MethylthiouracilNot Annotated
VorozoleNot Annotated
DroloxifeneDroloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more...
BaicaleinBaicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of...
FadrozoleNot Annotated
OrmeloxifeneA selective estrogen receptor modulator used as a non-hormonal, non-steroidal oral contraceptive.
SC 41930Not Annotated
Drugs & Drug Targets
AbarelixGonadotropin-releasing hormone receptortarget
FluconazoleCytochrome P450 3A4enzyme
FluconazoleCytochrome P450 2C9enzyme
FluconazoleCytochrome P450 2C19enzyme
FluconazoleP-glycoprotein 1transporter
FluconazoleCytochrome P450 51target
FluconazoleCytochrome P450 3A5enzyme
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
AminoglutethimideCytochrome P450 19A1target
AminoglutethimideCytochrome P450 2C19enzyme
AminoglutethimideCytochrome P450 3A4enzyme
AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
SpironolactoneMineralocorticoid receptortarget
SpironolactoneCytochrome P450 2C8enzyme
SpironolactoneCanalicular multispecific organic anion transporter 1transporter
SpironolactoneP-glycoprotein 1transporter
SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
SpironolactoneAndrogen receptortarget
SpironolactoneProgesterone receptortarget
SpironolactoneGlucocorticoid receptortarget
SpironolactoneNuclear receptor subfamily 1 group I member 2target
SpironolactoneBile salt export pumptransporter
SpironolactoneSerum albumincarrier
Spironolactonealpha1-acid glycoproteincarrier
SpironolactoneEstrogen receptortarget
SpironolactoneCytochrome P450 11B2, mitochondrialenzyme
SpironolactoneVoltage-dependent L-type calcium channeltarget
MontelukastCysteinyl leukotriene receptor 1target
MontelukastArachidonate 5-lipoxygenasetarget
MontelukastCytochrome P450 3A4enzyme
MontelukastCytochrome P450 2C9enzyme
MontelukastCytochrome P450 2C8enzyme
MontelukastSolute carrier organic anion transporter family member 2B1transporter
MontelukastProstaglandin G/H synthase 1enzyme
MontelukastCytochrome P450 2A6enzyme
RaloxifeneEstrogen receptor alphatarget
RaloxifeneEstrogen receptor betatarget
RaloxifeneAldehyde oxidaseenzyme
RaloxifeneCytochrome P450 2C8enzyme
RaloxifeneCytochrome P450 2B6enzyme
RaloxifeneCytochrome P450 19A1enzyme
RaloxifeneCytochrome P450 3A4enzyme
RaloxifeneSerpin B9target
RaloxifeneTrefoil factor 1target
RaloxifeneUDP-glucuronosyltransferase 1-1enzyme
RaloxifeneSerum albumincarrier
RaloxifeneAlpha-1-acid glycoprotein 1carrier
RaloxifeneSolute carrier organic anion transporter family member 1B1transporter
RaloxifeneSolute carrier organic anion transporter family member 1B3transporter
RaloxifeneP-glycoprotein 1transporter
RaloxifeneATP-binding cassette sub-family G member 2transporter
RaloxifeneCanalicular multispecific organic anion transporter 1transporter
RaloxifeneCanalicular multispecific organic anion transporter 2transporter
RaloxifeneMultidrug resistance-associated protein 4transporter
RaloxifeneUDP-glucuronosyltransferase 1-10enzyme
RaloxifeneUDP-glucuronosyltransferase 1-8enzyme
FlutamideAndrogen receptortarget
FlutamideCytochrome P450 1A2enzyme
FlutamideCytochrome P450 3A4enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 3A5enzyme
FlutamideAryl hydrocarbon receptortarget
FlutamideNuclear receptor subfamily 1 group I member 2target
FlutamideMultidrug resistance-associated protein 1transporter
ToremifeneEstrogen receptor alphatarget
ToremifeneCytochrome P450 3A4enzyme
ToremifeneP-glycoprotein 1transporter
ToremifeneCytochrome P450 1A1enzyme
ToremifeneSex hormone-binding globulintarget
NilutamideAndrogen receptortarget
NilutamideCytochrome P450 2C19enzyme
NilutamideNADPH--cytochrome P450 reductaseenzyme
TamoxifenEstrogen receptor alphatarget
TamoxifenEstrogen receptor betatarget
TamoxifenCytochrome P450 2C9enzyme
TamoxifenCytochrome P450 3A4enzyme
TamoxifenCytochrome P450 2D6enzyme
TamoxifenCytochrome P450 2C8enzyme
TamoxifenCytochrome P450 2B6enzyme
TamoxifenLiver carboxylesterase 1enzyme
TamoxifenCytochrome P450 3A5enzyme
TamoxifenCytochrome P450 1A1enzyme
TamoxifenCytochrome P450 1B1enzyme
TamoxifenCytochrome P450 2C19enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TamoxifenCytochrome P450 3A7enzyme
TamoxifenP-glycoprotein 1transporter
TamoxifenATP-binding cassette sub-family G member 2transporter
TamoxifenCytochrome P450 19A1enzyme
TamoxifenCytochrome P450 2A6enzyme
TamoxifenCytochrome P450 2E1enzyme
TamoxifenUDP-glucuronosyltransferase 1-10enzyme
TamoxifenSulfotransferase 1A1enzyme
TamoxifenCanalicular multispecific organic anion transporter 1transporter
TamoxifenProtein kinase Ctarget
TamoxifenAndrogen receptortarget
TamoxifenPotassium voltage-gated channel subfamily H member 2target
TamoxifenNuclear receptor subfamily 1 group I member 2target
TamoxifenEstrogen-related receptor gammatarget
TamoxifenSex hormone-binding globulintarget
TamoxifenBile salt export pumptransporter
TamoxifenThyroxine-binding globulincarrier
TamoxifenBile salt sulfotransferaseenzyme
TamoxifenCytochrome P450 1A2enzyme
TamoxifenUDP-glucuronosyltransferase 2B7enzyme
TamoxifenUDP-glucuronosyltransferase 2B17enzyme
TamoxifenEstrogen sulfotransferaseenzyme
TamoxifenATP-binding cassette sub-family A member 1transporter
TamoxifenMitogen-activated protein kinase 8target
TamoxifenSerum albumincarrier
EplerenoneMineralocorticoid receptortarget
EplerenoneCytochrome P450 3A4enzyme
EplerenoneCytochrome P450 3A5enzyme
EplerenoneCytochrome P450 11B2, mitochondrialenzyme
MethimazoleThyroid peroxidasetarget
MethimazoleCytochrome P450 1A2enzyme
MethimazoleCytochrome P450 2A6enzyme
MethimazoleCytochrome P450 2B6enzyme
MethimazoleCytochrome P450 2C19enzyme
MethimazoleCytochrome P450 2C9enzyme
MethimazoleCytochrome P450 2D6enzyme
MethimazoleCytochrome P450 2E1enzyme
MethimazoleCytochrome P450 3A4enzyme
MethimazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
FulvestrantEstrogen receptor alphatarget
FulvestrantCytochrome P450 3A4enzyme
FulvestrantUDP-glucuronosyltransferase 1-1enzyme
ExemestaneCytochrome P450 19A1target
ExemestaneCytochrome P450 3A4enzyme
ExemestaneCytochrome P450 19A1enzyme
LetrozoleCytochrome P450 19A1target
LetrozoleCytochrome P450 3A4enzyme
LetrozoleCytochrome P450 2A6enzyme
LetrozoleCytochrome P450 19A1enzyme
LetrozoleCytochrome P450 2C19enzyme
LetrozoleUDP-glucuronosyltransferase 2B7enzyme
LetrozoleSerum albumincarrier
LetrozoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DutasterideSodium-dependent dopamine transportertransporter
DutasterideSynaptic vesicular amine transportertransporter
DutasterideSerum albumincarrier
DutasterideAlpha-1-acid glycoprotein 1carrier
DutasterideCytochrome P450 3A5enzyme
BicalutamideAndrogen receptortarget
BicalutamideCytochrome P450 3A4enzyme
BicalutamideCytochrome P450 2C19enzyme
BicalutamideCytochrome P450 2C9enzyme
BicalutamideCytochrome P450 2D6enzyme
BicalutamideP-glycoprotein 1transporter
BromocriptineDopamine D2 receptortarget
BromocriptineCytochrome P450 3A4enzyme
Bromocriptine5-hydroxytryptamine receptor 1Dtarget
BromocriptineAlpha-2A adrenergic receptortarget
BromocriptineDopamine D3 receptortarget
Bromocriptine5-hydroxytryptamine receptor 1Atarget
BromocriptineAlpha-2C adrenergic receptortarget
BromocriptineAlpha-2B adrenergic receptortarget
Bromocriptine5-hydroxytryptamine receptor 2Btarget
BromocriptineDopamine D4 receptortarget
Bromocriptine5-hydroxytryptamine receptor 2Atarget
Bromocriptine5-hydroxytryptamine receptor 1Btarget
Bromocriptine5-hydroxytryptamine receptor 2Ctarget
BromocriptineDopamine D5 receptortarget
BromocriptineDopamine D1 receptortarget
BromocriptineAlpha-1A adrenergic receptortarget
BromocriptineAlpha-1B adrenergic receptortarget
BromocriptineAlpha-1D adrenergic receptortarget
Bromocriptine5-hydroxytryptamine receptor 7target
BromocriptineP-glycoprotein 1transporter
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
FinasterideCytochrome P450 3A4enzyme
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
FinasterideCytochrome P450 3A5enzyme
FinasterideCytochrome P450 3A7enzyme
FinasterideSolute carrier family 12 member 5transporter
AnastrozoleCytochrome P450 19A1target
AnastrozoleP-glycoprotein 1transporter
AnastrozoleCytochrome P450 3A4enzyme
AnastrozoleCytochrome P450 3A5enzyme
AnastrozoleCytochrome P450 2C8enzyme
AnastrozoleUDP-glucuronosyltransferase 1-4enzyme
AnastrozoleUDP-glucuronosyltransferase 1-3enzyme
AnastrozoleUDP-glucuronosyltransferase 2B7enzyme
AnastrozoleCytochrome P450 1A2enzyme
AnastrozoleCytochrome P450 2C9enzyme
DrospirenoneProgesterone receptortarget
DrospirenoneMineralocorticoid receptortarget
DrospirenoneAndrogen receptortarget
DrospirenoneProstaglandin G/H synthase 2enzyme
DrospirenoneSerum paraoxonase/arylesterase 1enzyme
DrospirenoneGlucocorticoid receptortarget
DrospirenoneCytochrome P450 3A4enzyme
Cyproterone acetateAndrogen receptortarget
Cyproterone acetateProstate-specific antigentarget
Cyproterone acetateCytochrome P450 3A4enzyme
Cyproterone acetateCytochrome P450 19A1enzyme
LintitriptCholecystokinin receptor type Atarget
AbirateroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
AbirateroneSerum albumincarrier
AbirateroneAlpha-1-acid glycoprotein 1carrier
AbirateroneCytochrome P450 3A4enzyme
AbirateroneBile salt sulfotransferaseenzyme
AbirateroneMultidrug resistance-associated protein 1transporter
AbirateroneCytochrome P450 2D6enzyme
AbirateroneCytochrome P450 2C8enzyme
AbirateroneCytochrome P450 1A2enzyme
AbirateroneCytochrome P450 2C19enzyme
AbirateroneCytochrome P450 2C9enzyme
AbirateroneCytochrome P450 3A5enzyme
AbirateroneSolute carrier organic anion transporter family member 1B1transporter
GanirelixGonadotropin-releasing hormone receptortarget
FormestaneCytochrome P450 3A4enzyme
TiboloneEstrogen receptor alphatarget
Tibolone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1enzyme
Tibolone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
TiboloneSulfotransferase 1A1enzyme
TiboloneSerum albumincarrier
OnapristoneGlucocorticoid receptortarget
OnapristoneProbable G-protein coupled receptor 133target
ChlormadinoneCytochrome P450 3A4enzyme
RelcovaptanOxytocin receptortarget
RelcovaptanVasopressin V1a receptortarget
TeverelixGonadotropin-releasing hormone receptortarget
RelugolixSerum albumincarrier
RelugolixAlpha-1-acid glycoprotein 1carrier
RelugolixP-glycoprotein 1transporter
RelugolixATP-binding cassette sub-family G member 2transporter
RelugolixCytochrome P450 3A Subfamilyenzyme
RelugolixCytochrome P450 2C8enzyme
RelugolixCytochrome P450 2B6enzyme
RelugolixGonadotropin-releasing hormone receptortarget
CetrorelixLutropin-choriogonadotropic hormone receptortarget
CetrorelixGonadotropin-releasing hormone receptortarget
MifepristoneProgesterone receptortarget
MifepristoneGlucocorticoid receptortarget
MifepristoneCytochrome P450 3A4enzyme
MifepristoneCytochrome P450 3A5enzyme
MifepristoneP-glycoprotein 1transporter
MifepristoneMultidrug resistance-associated protein 1transporter
MifepristoneCytochrome P450 2D6enzyme
MifepristoneProstate-specific antigentarget
MifepristoneNuclear receptor subfamily 1 group I member 2target
MifepristoneBile salt export pumptransporter
MifepristoneCytochrome P450 2C8enzyme
MifepristoneCytochrome P450 2C9enzyme
MifepristoneSolute carrier organic anion transporter family member 1B1transporter
MifepristoneSolute carrier organic anion transporter family member 1B3transporter
AtosibanOxytocin receptortarget
AtosibanVasopressin V1a receptortarget
AtosibanVasopressin V1b receptortarget
AtosibanVasopressin V2 receptortarget
DienogestCytochrome P450 3A4enzyme
DienogestProgesterone receptortarget
DienogestAndrogen receptortarget
CarbimazoleThyroid peroxidasetarget
CarbimazoleCytochrome P450 19A1enzyme
ZafirlukastCysteinyl leukotriene receptor 1target
ZafirlukastCytochrome P450 2C9enzyme
ZafirlukastCytochrome P450 2C8enzyme
ZafirlukastProstaglandin G/H synthase 1enzyme
ZafirlukastCytochrome P450 3A4enzyme
ZafirlukastCytochrome P450 1A2enzyme
ZafirlukastCytochrome P450 2C19enzyme
ZafirlukastATP-binding cassette sub-family G member 2transporter
ZafirlukastCytochrome P450 2D6enzyme
ZafirlukastSodium/bile acid cotransportertransporter
PropylthiouracilThyroid peroxidasetarget
PropylthiouracilDopamine beta-hydroxylaseenzyme
PropylthiouracilCytochrome P450 1A1enzyme
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
ClomifeneEstrogen receptor alphatarget
ClomifeneP-glycoprotein 1transporter
ClomifeneSex hormone-binding globulintarget
ClomifeneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleCytochrome P450 3A4enzyme
ItraconazoleCytochrome P450 3A5enzyme
ItraconazoleCytochrome P450 3A7enzyme
ItraconazoleCytochrome P450 2B6enzyme
ItraconazoleP-glycoprotein 1transporter
ItraconazoleCytochrome P450 1A1enzyme
ItraconazoleCytochrome P450 2E1enzyme
ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
ItraconazoleCytochrome P450 3A Subfamilyenzyme
PosaconazoleCytochrome P450 3A4enzyme
PosaconazoleP-glycoprotein 1transporter
PosaconazoleCytochrome P450 51target
DanazolEstrogen receptor alphatarget
DanazolGonadotropin-releasing hormone receptortarget
DanazolPutative gonadotropin-releasing hormone II receptortarget
DanazolSex hormone-binding globulincarrier
DanazolC-C motif chemokine 2target
DanazolCytochrome P450 19A1enzyme
DanazolAndrogen receptortarget
DanazolProgesterone receptortarget
DanazolCytochrome P450 3A4enzyme
PranlukastTumor necrosis factortarget
PranlukastEosinophil cationic proteintarget
PranlukastNuclear factor NF-kappa-B p105 subunittarget
PranlukastCysteinyl leukotriene receptor 1target
PranlukastCytochrome P450 3A4enzyme
PranlukastCanalicular multispecific organic anion transporter 1transporter
PranlukastCytochrome P450 2C9enzyme
PranlukastNuclear factor NF-kappa-Btarget
NaringeninSolute carrier organic anion transporter family member 2B1transporter
NaringeninP-glycoprotein 1transporter
NaringeninMultidrug resistance-associated protein 1transporter
NaringeninATP-binding cassette sub-family G member 2transporter
NaringeninHTH-type transcriptional regulator TtgRtarget
NaringeninEstrogen receptor alphatarget
NaringeninAldo-keto reductase family 1 member C1target
NaringeninCytochrome P450 1B1target
NaringeninKAT8 regulatory NSL complex subunit 3target
NaringeninSex hormone-binding globulintarget
NaringeninCytochrome P450 19A1target
NaringeninEstrogen receptor betatarget
ICI-164384Estrogen receptor betatarget
AfimoxifeneEstrogen receptor alphatarget
AfimoxifeneEstrogen receptor betatarget
AfimoxifeneEstrogen-related receptor gammatarget
AfimoxifeneTrefoil factor 1target
AfimoxifeneSteroid hormone receptor ERR1target
AfimoxifeneNuclear receptor subfamily 1 group I member 2target
AfimoxifeneSex hormone-binding globulintarget
BazedoxifeneEstrogen receptor alphatarget
BazedoxifeneUDP-glucuronosyltransferase 1-4enzyme
BazedoxifeneEstrogen receptor betatarget
BazedoxifeneUDP-glucuronosyltransferase 1-8enzyme
BazedoxifeneUDP-glucuronosyltransferase 1-10enzyme
EnclomipheneCytochrome P450 2D6enzyme
SeratrodastCytochrome P450 2C9enzyme
SeratrodastCytochrome P450 3A4enzyme
SeratrodastCytochrome P450 2C8enzyme
SeratrodastCytochrome P450 2C19enzyme
SeratrodastCytochrome P450 2B6enzyme
SeratrodastUDP-glucuronosyltransferase 1-9enzyme
SeratrodastProstaglandin G/H synthase 1enzyme
SeratrodastCytochrome P450 2A6enzyme
SeratrodastThromboxane A2 receptortarget
Hydroxyprogesterone caproateProgesterone receptortarget
Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
Hydroxyprogesterone caproateCytochrome P450 2C19enzyme
WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
WortmanninSerine/threonine-protein kinase PLK1target
WortmanninPhosphatidylinositol 3-kinase regulatory subunit alphatarget
WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
OrmeloxifeneEstrogen receptor alphatarget
OrmeloxifeneEstrogen receptor betatarget
OrmeloxifeneSerum albumincarrier