Prasterone enantate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Prasterone enantate is an estrogen indicated for hormone replacement therapy in postmenopausal women.

Generic Name
Prasterone enantate
DrugBank Accession Number
DB16625
Background

Not Available

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 400.603
Monoisotopic: 400.297745148
Chemical Formula
C26H40O3
Synonyms
  • Dehydroepiandrosterone enanthate
  • DHEA enantate
  • DHEA enanthate
  • Prasterone enanthate
External IDs
  • 245-970-8

Pharmacology

Indication

Not Available

Pharmacology
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Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Beclomethasone dipropionateThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Beclomethasone dipropionate.
BetamethasoneThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Betamethasone.
Betamethasone phosphateThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Betamethasone phosphate.
BudesonideThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Budesonide.
CiclesonideThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Ciclesonide.
Clobetasol propionateThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Clobetasol propionate.
CorticotropinThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Corticotropin.
Cortisone acetateThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Cortisone acetate.
DeflazacortThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Deflazacort.
DesoximetasoneThe risk or severity of edema formation can be increased when Prasterone enantate is combined with Desoximetasone.
Interactions
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Food Interactions
Not Available

Products

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Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
2W8I1S6T5L
CAS number
23983-43-9
InChI Key
HHENOUDBWKNPAB-BNCSLUSBSA-N
InChI
InChI=1S/C26H40O3/c1-4-5-6-7-8-24(28)29-19-13-15-25(2)18(17-19)9-10-20-21-11-12-23(27)26(21,3)16-14-22(20)25/h9,19-22H,4-8,10-17H2,1-3H3/t19-,20-,21-,22-,25-,26-/m0/s1
IUPAC Name
(3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-oxo-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl heptanoate
SMILES
[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCCCCC

References

General References
  1. BASG: Gynodian Depot - Fertigspritze (Estradiol Valerate, Prasterone Enantate) Intramuscular Injection [Link]
ChemSpider
143333
ZINC
ZINC000005820240
Wikipedia
Prasterone_enanthate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP6.28ChemAxon
pKa (Strongest Basic)-6.9ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area43.37 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity116.84 m3·mol-1ChemAxon
Polarizability48.28 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on February 24, 2021 21:46 / Updated on April 30, 2021 13:08