Indicators and Reagents
- Indicators and Reagents
- Accession Number
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Drug Drug Description Capromab pendetide A monoclonal anti-prostate specific membrane antigen antibody used in imaging kits to target radioactive agents to malignant prostate tissue. Amsacrine A cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents. Mitomycin An antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies. Nitroprusside A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure. Aminohippuric acid A hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system. Cisplatin A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Bentiromide Indicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. Methoxsalen A furocoumarin used to treat psoriasis and vitiligo. Fluorescein A dye used in angiography or angioscopy of the iris and retina. Carboplatin A alkylating agent used to treat advanced ovarian cancer. Sorbitol A product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. Dithioerythritol A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl... Isoluminol Not Available Propidium Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent... 1,10-Phenanthroline Not Available 4-nitrophenyl-beta-D-galactoside Not Available Dansylamide Not Available Acetic acid An antimicrobial agent used to treat susceptible infections of the external auditory canal. Picric acid Used as antiseptic, astringent, and stimulant for epitheliazation. Rhodamine 6G Not Available Oxalic Acid A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted... Indole-3-Glycerol Phosphate Not Available 4-Nitrophenyl Phosphate Not Available Phenolphthalein A drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. Amonafide Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer. Iobenguane A radiopharmaceutical agent used for the diagnosis of primary and metastatic pheochromocytoma or neuroblastoma. Plicamycin For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer. Hymecromone A coumarin derivative that lacks anticoagulant properties but possesses choleretic and biliary antispasmodic activity. Ferulic acid Not Available Nitrous acid An iron binder used to reverse life-threatening acute cyanide poisoning. Technetium Tc-99m mebrofenin A diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests. Technetium Tc-99m medronate A diagnostic radiopharmaceutical agent used as a bone imaging agent to delineate areas of altered osteogenesis. Technetium Tc-99m sestamibi A radiopharmaceutical diagnostic agent used in nuclear medicine imaging tests to detect coronary artery disease and evaluate myocardial function. Technetium Tc-99m exametazime A radiopharmaceutical diagnostic agent used as an adjunct for scintigraphy in the detection of altered regional cerebral perfusion in stroke. Technetium Tc-99m disofenin A radiopharmaceutical diagnostic agent used for hepatobiliary scans. Technetium Tc-99m pyrophosphate A radiopharmaceutical diagnostic agent used for diagnostic imaging scans for the bones, heart, and gastrointestinal tract. Technetium Tc-99m pertechnetate A radiocontrast agent used for the identification of various organs, including but not limited to the brain, thyroid, placenta, and bladder. Technetium Tc-99m sulfur colloid A radiopharmaceutical diagnostic agent used for the localization of lymph nodes, evaluation of peritoneovenous (LeVeen) shunt patency, imaging areas of functioning reticuloendothelial cells, and gastrointestinal imaging. Technetium Tc-99m etidronate Not Annotated Iofetamine I-123 Not Annotated Fludeoxyglucose (18F) A radiopharmaceutical agent used for positron emission tomography (PET) imaging in oncology, cardiology, and neurology. Potassium hydroxide A disinfectant used to clean hands, skin, and surfaces. DL-dimyristoylphosphatidylcholine DL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication. Dithiazanine Not Annotated Aminacrine A slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties. Nitrocefin Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin... Tuberculin purified protein derivative A purified protein used in the Mantoux test for Mycobacterium tuberculosis testing. Dinitrochlorobenzene Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections. Bizelesin Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Pyrazoloacridine Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others. Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Phloroglucinol A spasmolytic agent to treat colic, as well as spastic pain of the digestive and biliary tracts. Phenolsulfonphthalein Phenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories. Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions... Sulfobromophthalein Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans . Eosin A medication used to disinfect small skin wounds, bug bites, and sores. Potassium permanganate Not Annotated Phloxine B For use in dental disclosing products, allowing for highlighting of bacterial placques. Bronopol An antimicrobial compound used as a biocide and preservative. p-Phenylenediamine Not Annotated Tosylchloramide A chlorinated disinfectant of the genitals and injured skin. Platinum Platinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine... Quinacrine mustard Not Available Glycocyamine Not Available Adenosine 5'-[gamma-thio]triphosphate A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur. Glutaral One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative. Flutemetamol (18F) A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. Technetium Tc-99m tetrofosmin Technetium-99m tetrofosmin is indicated for the diagnosis of heart abnormalities by exercise myocardial scintigraphy. The exercise myocardial scintigraphy is an established method for the diagnosis of the severity of coronary... Bevacizumab zirconium Zr-89 Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors). Flutemetamol Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning). Fluoroazomycin arabinoside F-18 Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer). Afamelanotide An injectable subcutaneous implant used to mitigate phototoxicity secondary to erythropoietic protoporphyria (EPP). Rose bengal Indicated as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected, and as an aid in the diagnosis of keratoconjunctivitis sicca, keratitis,... Brilliant blue G A disclosing agent used in ophthalmological surgery to stain the internal limiting membrane (ILM). Coumarin 120 Not Available Sinapic acid Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis. 8-anilinonaphthalene-1-sulfonic acid Not Available Acriflavine A topical antiseptic indicated in the treatment of infected wounds and for skin disinfection.
- Drugs & Drug Targets