Aniline Compounds

Name
Aniline Compounds
Accession Number
DBCAT000637
Description

Compounds that include the aminobenzene structure.

Drugs
DrugDrug Description
2-AminophenolNot Available
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideNot Available
4-(Isopropylamino)diphenylamine4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
4-dimethylaminophenolNot Annotated
4,5-Dimethyl-1,2-phenylenediamineNot Available
8-anilinonaphthalene-1-sulfonic acidNot Available
ABT-751ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...
AcetyldinalineAcetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
AcoltremonAcoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512).
AltiratinibNot Annotated
AmbroxolA medication indicated for airway secretion clearance therapy.
Ambroxol acefyllinateA bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm.
AmitrazAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as...
AmoscanateAmoscanate is a small molecule drug. Amoscanate has a monoisotopic molecular weight of 271.04 Da.
AndarineAndarine is a non-steroidal selective androgen receptor modulator.
AzosemideAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
BenorilateNot Annotated
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
BirabresibBirabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
Brilliant blue GA disclosing agent used in ophthalmological surgery to stain the internal limiting membrane (ILM).
BromhexineA mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance.
BucetinBucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.
BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
ButanilicaineNot Annotated
CabozantinibA tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
CarboxinA systemic agricultural fungicide and seed treatment agent.
ChlorsulfaquinoxalineChlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer.
ClioxanideClioxanide is a small molecule drug. Clioxanide has a monoisotopic molecular weight of 540.84 Da.
CloflucarbanCloflucarban is a small molecule drug. Cloflucarban has a monoisotopic molecular weight of 348.0 Da.
ClorsulonNot Annotated
CrotamitonA topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus.
DiacetamateDiacetamate is a small molecule drug. Diacetamate has a monoisotopic molecular weight of 193.07 Da.
DiamfenetideDiamfenetide is a small molecule drug. Diamfenetide has a monoisotopic molecular weight of 372.17 Da.
DibromsalanDibromsalan is a small molecule drug. Dibromsalan has a monoisotopic molecular weight of 368.9 Da.
Diethylamino hydroxybenzoyl hexyl benzoateIndicated for use as a sunscreen agent.
DulozafoneDulozafone is a small molecule drug. The usage of the INN stem '-zafone' in the name indicates that Dulozafone is a alozafone derivative. Dulozafone has a monoisotopic molecular weight of...
EflucimibeEflucimibe is a small molecule drug. Eflucimibe has a monoisotopic molecular weight of 469.3 Da.
ElsulfavirineElsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact...
EncainideA voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
EnobosarmEnobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer.
EprotiromeInvestigated for use/treatment in hyperlipidemia, metabolic disease, and obesity.
EtersalateEtersalate is a small molecule drug. Etersalate has a monoisotopic molecular weight of 357.12 Da.
EtidocaineEtidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage...
EzogabineAn antiepileptic agent used as an adjuvant treatment of partial-onset seizures.
FasentinNot Annotated
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
ForetinibForetinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally...
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
Gentian violet cationAn antiseptic violet dye used to prevent various infections, including fungal and bacterial infections.
ImidocarbImidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
Inosine pranobexA medication used to treat subacute sclerosing panencephalitis.
Isosulfan blueA visual lymphatic imaging agent used during lymphography as an adjunct.
IvacaftorA cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication.
LevobupivacaineA drug used for nerve block and anesthesia.
LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
Malachite GreenNot Available
MebenilAn obsolete fungicide used to control various pathogens on cereals and seed potatoes.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
MetabromsalanNot Annotated
MethfuroxamMethfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma).
MirabegronA beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.
MirdametinibA kinase inhibitor used to treat neurofibromatosis type 1 in children and adults.
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamineN-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
N,N'-diphenyl-1,4-phenylenediamineNot Annotated
NCX 701Investigated for use/treatment in pain (acute or chronic).
NeltenexineNeltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema.
NicarbazinNot Annotated
NiclosamideAn anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
NS-3728Investigated for use/treatment in anemia (sickle cell) and cancer/tumors (unspecified).
OmbitasvirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
OrludodstatOrludodstat is a small molecule drug. The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor. Orludodstat is under investigation in...
OxyclozanideOxyclozanide is a small molecule drug. Oxyclozanide has a monoisotopic molecular weight of 398.88 Da.
p-AminophenolNot Annotated
p-PhenylenediamineNot Annotated
ParapropamolParapropamol is a small molecule drug. Parapropamol has a monoisotopic molecular weight of 165.08 Da.
Patent BlueA dye used to label lymphatic vessels, arterial territories, and lymph nodes prior to biopsy in some cancers.
PhenacetinUsed principally as an analgesic.
PhthalylsulfathiazoleA sulfonamide antibacterial indicated in the treatment of gastrointestinal infections.
PilsicainidePilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
PincainidePincainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Pincainide is a class I antiarrhythmic, procainamide and lidocaine derivative. Pincainide has...
PlatensimycinNot Available
PractololUsed in the emergency treatment of cardiac arrhythmias.
PrilocaineA local anesthetic used in dental procedures.
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
PyrrocainePyrrocaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Pyrrocaine is a local anaesthetic. Pyrrocaine has a monoisotopic molecular weight of...
RafoxanideRafoxanide is a small molecule drug. Rafoxanide has a monoisotopic molecular weight of 624.82 Da.
RefametinibInvestigated for use/treatment in cancer/tumors (unspecified).
ResorantelResorantel is a small molecule drug. The usage of the INN stem '-antel' in the name indicates that Resorantel is a anthelminthic. Resorantel has a monoisotopic molecular weight of 306.98...
RisotilideRisotilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Risotilide is a sematilide derivative class III antiarrhythmic. Risotilide has a monoisotopic...
RobenacoxibRobenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
RopivacaineAn amide-type local anesthetic used for local or regional anesthesia during surgery and for short-term management of acute pain.
S-23An androgen receptor modulator.
SalicylanilideNot Annotated
SemapimodSemapimod has been used in trials studying the treatment of Crohn Disease.
Silver sulfadiazineA topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
SitravatinibSitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
SuccinylsulfathiazoleNot Annotated
SulfacarbamideSulfacarbamide is a small molecule drug. Sulfacarbamide has a monoisotopic molecular weight of 215.04 Da.
SulfacetamideA sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.
SulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
SulfaclomideSulfaclomide is a small molecule drug. Sulfaclomide has a monoisotopic molecular weight of 312.04 Da.
SulfaclozineSulfaclozine is a small molecule drug. Sulfaclozine has a monoisotopic molecular weight of 284.01 Da.
SulfacytineUsed orally in the treatment of acute urinary tract infections.
SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
SulfadimethoxineFor use in the treatment of infections.
SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
SulfaethoxypyridazineNot Annotated
SulfaguanidineSulfaguanidine is a sulfonamide antibiotic with antimicrobial and antibacterial activities.
SulfaisodimidineSulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has...
SulfamerazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
SulfamethazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
SulfamethoxazoleAn oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
SulfamethoxypyridazineA sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis.
SulfametopyrazineAn antibiotic used in the treatment or prevention of bacterial infections and malaria.
SulfametroleAn antibiotic indicated in combination intravenous products for various bacterial infections.
SulfamoxoleFor the treatment of bacterial infection.
SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
SulfanitranNot Annotated
SulfaphenazoleFor the treatment bacterial infections.
SulfaproxylineSulfaproxyline is a small molecule drug. Sulfaproxyline has a monoisotopic molecular weight of 334.1 Da.
SulfapyridineA sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.
SulfaquinoxalineSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K...
SulfasymazineSulfasymazine is a small molecule drug. Sulfasymazine has a monoisotopic molecular weight of 307.11 Da.
SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
SulfathioureaNot Annotated
SulfatolamideNot Annotated
SulfatroxazoleSulfatroxazole is a small molecule drug. Sulfatroxazole has a monoisotopic molecular weight of 267.07 Da.
SulfisoxazoleA sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
TacedinalineTacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
TefinostatTefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)).
TeriflunomideA pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
TocainideAn orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
TribromsalanTribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da.
TriclocarbanAn antibacterial agent used in liquid soaps and body washes.
VismodegibA hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
ZapnometinibNot Annotated
Drugs & Drug Targets
DrugTargetType
2-AminophenolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideHistone deacetylase 8target
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideDopamine receptor D2target
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideDopamine receptor D3target
4-dimethylaminophenolDisks large homolog 4target
4,5-Dimethyl-1,2-phenylenediamineNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
8-anilinonaphthalene-1-sulfonic acidFatty acid-binding protein, livertarget
8-anilinonaphthalene-1-sulfonic acidTransthyretincarrier
8-anilinonaphthalene-1-sulfonic acidProtein S100-A7target
8-anilinonaphthalene-1-sulfonic acidFatty acid-binding protein, adipocytecarrier
8-anilinonaphthalene-1-sulfonic acidUDP-N-acetylglucosamine 1-carboxyvinyltransferasetarget
ABT-751Tubulin beta chaintarget
ABT-751Tubulintarget
ABT-751UDP-glucuronosyltransferase 1A8enzyme
ABT-751UDP-glucuronosyltransferase 1A4enzyme
ABT-751UDP-glucuronosyltransferase 1A1enzyme
AcetaminophenFatty-acid amide hydrolase 1enzyme
AcetaminophenProstaglandin G/H synthase 1target
AcetaminophenProstaglandin G/H synthase 2target
AcetaminophenCytochrome P450 1A2enzyme
AcetaminophenCytochrome P450 2E1enzyme
AcetaminophenATP-dependent translocase ABCB1transporter
AcetaminophenCytochrome P450 2D6enzyme
AcetaminophenCytochrome P450 2A6enzyme
AcetaminophenCytochrome P450 3A4enzyme
AcetaminophenUDP-glucuronosyltransferase 1A1enzyme
AcetaminophenUDP-glucuronosyltransferase 1A6enzyme
AcetaminophenUDP-glucuronosyltransferase 1A9enzyme
AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
AcetaminophenSulfotransferase 1A1enzyme
AcetaminophenSulfotransferase 1A3enzyme
AcetaminophenArylamine N-acetyltransferase 2enzyme
AcetaminophenProstaglandin E synthase 3target
AcetaminophenTransient receptor potential cation channel subfamily V member 1target
AcetaminophenAlbumincarrier
AcetaminophenFatty-acid amide hydrolase 1target
AcetaminophenGlutathione S-transferase Penzyme
AcetaminophenGlutathione S-transferase Mu 1enzyme
AcetaminophenSodium-dependent noradrenaline transportertarget
AcetaminophenSodium-dependent serotonin transportertarget
AcetaminophenHuman Cyclooxygenasestarget
Acetyl sulfisoxazoleDihydropteroate synthasetarget
Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
AcetyldinalineHistone deacetylasetarget
AcoltremonTransient receptor potential cation channel subfamily M member 8target
AltiratinibHepatocyte growth factor receptortarget
AltiratinibNT-3 growth factor receptortarget
AltiratinibHigh affinity nerve growth factor receptortarget
AltiratinibVascular endothelial growth factor receptor 2target
AltiratinibAngiopoietin-1 receptortarget
AmbroxolTransient receptor potential cation channel subfamily A member 1target
AmbroxolTransient receptor potential cation channel subfamily V member 1target
AmbroxolSodium channel protein type 9 subunit alphatarget
AmbroxolSodium channel protein type 10 subunit alphatarget
AmbroxolNon-lysosomal glucosylceramidasetarget
AmbroxolLysosomal acid glucosylceramidasetarget
AmbroxolCytochrome P450 3A4enzyme
Ambroxol acefyllinateCytochrome P450 3A Subfamilyenzyme
Ambroxol acefyllinatePhospholipase A2, membrane associatedtarget
AmitrazAlpha-2 adrenergic receptorstarget
AmitrazMonoamine oxidasetarget
AndarineAndrogen receptortarget
AzosemideLactoylglutathione lyaseenzyme
AzosemideAlbumincarrier
AzosemideMonocarboxylate transporter 6transporter
AzosemideCytochrome P450 1A2enzyme
AzosemideSolute carrier family 12 member 2target
BicalutamideATP-dependent translocase ABCB1transporter
BicalutamideCytochrome P450 2D6enzyme
BicalutamideCytochrome P450 2C9enzyme
BicalutamideCytochrome P450 2C19enzyme
BicalutamideCytochrome P450 3A4enzyme
BicalutamideAndrogen receptortarget
BirabresibBromodomain-containing protein 4target
BirabresibBromodomain-containing protein 2target
Brilliant blue GInternal limiting membrane (ILM)target
BromhexineTransmembrane protease serine 2target
BromhexineAngiotensin-converting enzyme 2enzyme
BromhexineAngiotensin-converting enzyme 2target
BupivacaineSodium channel protein type 4 subunit alphatarget
BupivacaineCytochrome P450 2D6enzyme
BupivacaineCytochrome P450 2C19enzyme
BupivacaineCytochrome P450 3A4enzyme
BupivacaineProstaglandin E2 receptor EP1 subtypetarget
BupivacaineSodium channel protein type 10 subunit alphatarget
CabozantinibMast/stem cell growth factor receptor Kittarget
CabozantinibCytochrome P450 3A4enzyme
CabozantinibCytochrome P450 2C9enzyme
CabozantinibHepatocyte growth factor receptortarget
CabozantinibVascular endothelial growth factor receptor 2target
CabozantinibAngiopoietin-1 receptortarget
CabozantinibTyrosine-protein kinase Mertarget
CabozantinibTyrosine-protein kinase receptor TYRO3target
CabozantinibProto-oncogene tyrosine-protein kinase receptor Rettarget
CabozantinibCytochrome P450 2C8enzyme
CabozantinibVascular endothelial growth factor receptor 1target
CabozantinibVascular endothelial growth factor receptor 3target
CabozantinibBDNF/NT-3 growth factors receptortarget
CabozantinibReceptor-type tyrosine-protein kinase FLT3target
CabozantinibTyrosine-protein kinase receptor UFOtarget
CabozantinibProto-oncogene tyrosine-protein kinase ROStarget
CarboxinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
ChlorsulfaquinoxalineDNA topoisomerase 2-alphatarget
ChlorsulfaquinoxalineDNA topoisomerase 2-betatarget
ClorsulonCarbonic anhydrase 1target
CrotamitonTransient receptor potential cation channel subfamily V member 4target
DiacetamateTriacylglycerol lipaseenzyme
EflucimibeLiver carboxylesterase 1target
ElsulfavirineReverse transcriptase/RNaseHtarget
ElsulfavirineAdenylosuccinate lyasetarget
ElsulfavirineInsulin-induced gene 1 proteintarget
ElsulfavirineInsulin-induced gene 2 proteintarget
EncainideVoltage-gated sodium channel alpha subunittarget
EncainideCytochrome P450 2D6enzyme
EncainideSodium channel protein type 5 subunit alphatarget
EnobosarmAndrogen receptortarget
EprotiromeThyroid hormone receptor betatarget
EprotiromeThyroid hormone receptor alphatarget
EtersalateAmyloid-beta precursor proteintarget
EtidocaineVoltage-gated sodium channel alpha subunittarget
EzogabinePotassium voltage-gated channel subfamily KQT member 5target
EzogabineUDP-glucuronosyltransferase 1A4enzyme
EzogabineUDP-glucuronosyltransferase 1A9enzyme
EzogabinePotassium voltage-gated channel subfamily KQT member 4target
EzogabinePotassium voltage-gated channel subfamily KQT member 3target
EzogabinePotassium voltage-gated channel subfamily KQT member 2target
EzogabineArylamine N-acetyltransferase 2enzyme
EzogabineUDP-glucuronosyltransferase 1A3enzyme
EzogabineUDP-glucuronosyltransferase 1A1enzyme
FasentinSolute carrier family 2, facilitated glucose transporter member 1target
FlutamideATP-binding cassette sub-family C member 1transporter
FlutamideNuclear receptor subfamily 1 group I member 2target
FlutamideAryl hydrocarbon receptortarget
FlutamideCytochrome P450 3A5enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideAndrogen receptortarget
FlutamideCytochrome P450 1A2enzyme
FlutamideCytochrome P450 3A4enzyme
ForetinibAngiopoietin-1 receptortarget
ForetinibMast/stem cell growth factor receptor Kittarget
ForetinibReceptor-type tyrosine-protein kinase FLT3target
ForetinibHepatocyte growth factor receptortarget
ForetinibCytochrome P450 3A Subfamilyenzyme
ForetinibVascular endothelial growth factor receptor 2target
ForetinibHepatocyte growth factortarget
ForetinibVascular endothelial growth factor receptortarget
FurosemideAlbumincarrier
FurosemideSolute carrier family 12 member 1target
FurosemideSolute carrier family 22 member 6transporter
FurosemideOrganic cation/carnitine transporter 2transporter
FurosemideUDP-glucuronosyltransferase 1A1enzyme
FurosemideCarbonic anhydrase 2target
FurosemideOrganic anion transporter 3transporter
FurosemideATP-binding cassette sub-family C member 2transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideG protein-coupled receptor 35target
FurosemideThyroxine-binding globulincarrier
Gentian violet cationSolute carrier family 22 member 1transporter
Gentian violet cationDNAtarget
ImidocarbAcetylcholinesterasetarget
Inosine pranobexCyclic nucleotide phosphodiesterasetarget
Isosulfan blueAlbumincarrier
IvacaftorCytochrome P450 2C9enzyme
IvacaftorCytochrome P450 3A5enzyme
IvacaftorATP-dependent translocase ABCB1transporter
IvacaftorAlpha-1-acid glycoprotein 1carrier
IvacaftorAlbumincarrier
IvacaftorCytochrome P450 3A4enzyme
IvacaftorCystic fibrosis transmembrane conductance regulatortarget
LevobupivacaineSodium channel protein type 4 subunit alphatarget
LevobupivacaineCytochrome P450 1A2enzyme
LevobupivacaineCytochrome P450 3A4enzyme
LevobupivacaineSodium channel protein type 10 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 1target
LidocaineVoltage-gated sodium channel alpha subunittarget
LidocaineSodium channel protein type 11 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 2target
LidocaineSodium channel protein type 4 subunit alphatarget
LidocaineSodium channel protein type 9 subunit alphatarget
LidocaineCytochrome P450 2C9enzyme
LidocaineSodium channel protein type 5 subunit alphatarget
LidocaineEpidermal growth factor receptortarget
LidocaineCytochrome P450 1A2enzyme
LidocaineSodium channel protein type 10 subunit alphatarget
LidocaineCytochrome P450 2C8enzyme
LidocaineCytochrome P450 2B6enzyme
LidocaineCytochrome P450 2A6enzyme
LidocaineATP-dependent translocase ABCB1transporter
LidocaineOrganic cation/carnitine transporter 2transporter
LidocaineCytochrome P450 3A7enzyme
LidocaineCytochrome P450 3A5enzyme
LidocaineCytochrome P450 3A4enzyme
LidocaineCytochrome P450 2D6enzyme
Malachite GreenHTH-type transcriptional regulator QacRtarget
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidAlbumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1A9enzyme
Mefenamic acidCytochrome P450 1A2enzyme
Mefenamic acidUDP-glucuronosyltransferase 2B7enzyme
Mefenamic acidHuman Cyclooxygenasestarget
MirabegronSolute carrier family 22 member 2transporter
MirabegronSolute carrier family 22 member 1transporter
MirabegronUDP-glucuronosyltransferase 1A8enzyme
MirabegronUDP-glucuronosyltransferase 1A3enzyme
MirabegronSolute carrier family 22 member 3transporter
MirabegronBeta-3 adrenergic receptortarget
MirabegronCholinesteraseenzyme
MirabegronAlpha-1-acid glycoprotein 1carrier
MirabegronAlbumincarrier
MirabegronSolute carrier organic anion transporter family member 1A2transporter
MirabegronATP-dependent translocase ABCB1transporter
MirabegronCytochrome P450 2D6enzyme
MirabegronCytochrome P450 3A4enzyme
MirabegronBeta-1 adrenergic receptortarget
MirabegronUDP-glucuronosyltransferase 2B7enzyme
MirdametinibCarboxylesteraseenzyme
MirdametinibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
MirdametinibATP-dependent translocase ABCB1transporter
MirdametinibDual specificity mitogen-activated protein kinase kinase 2target
MirdametinibUDP-glucuronosyltransferase 2B7enzyme
MirdametinibUDP-glucuronosyltransferase 1A6enzyme
MirdametinibDual specificity mitogen-activated protein kinase kinase 1target
N,N'-diphenyl-1,4-phenylenediamineApolipoprotein B-100target
NCX 701Prostaglandin G/H synthase 1target
NCX 701Prostaglandin G/H synthase 2target
NeltenexineElectrogenic sodium bicarbonate cotransporter 1target
NeltenexineSolute carrier family 12 member 2target
NeltenexineElectroneutral sodium bicarbonate exchanger 1target
NicarbazinLipoprotein lipasetarget
NicarbazinProtein-glutamine gamma-glutamyltransferase 4target
NiclosamideCytochrome P450 1A2enzyme
NiclosamideCytochrome P450 2C9enzyme
NiclosamideDNAtarget
NS-3728Anoctamin-1target
NS-3728Volume-regulated anion channel subunit LRRC8Atarget
OmbitasvirATP-dependent translocase ABCB1transporter
OmbitasvirGenome polyproteintarget
OmbitasvirUDP-glucuronosyltransferase 1A1enzyme
OmbitasvirBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
OmbitasvirCytochrome P450 2C8enzyme
OmbitasvirNonstructural protein 5Atarget
OrludodstatDihydroorotate dehydrogenase (quinone), mitochondrialtarget
OxyclozanideProtein S100-A4target
OxyclozanideProtein S100-A9target
p-AminophenolCarbonic anhydrase 14target
p-PhenylenediamineOrnithine decarboxylasetarget
p-PhenylenediamineMyeloperoxidaseenzyme
p-PhenylenediamineCatalaseenzyme
p-PhenylenediamineCeruloplasminenzyme
p-PhenylenediamineArylamine N-acetyltransferase 2enzyme
p-PhenylenediamineArylamine N-acetyltransferase 1enzyme
Patent BlueAlbumintarget
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinCytochrome P450 3A4enzyme
PhenacetinInosine-5'-monophosphate dehydrogenase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 2E1enzyme
PhthalylsulfathiazoleDihydropteroate synthasetarget
PilsicainideVoltage-gated inwardly rectifying potassium channel KCNH2target
PilsicainideBile salt export pumptransporter
PilsicainideSodium channel protein type 5 subunit alphatarget
PilsicainideVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PilsicainideProteasome subunit beta type-5target
Platensimycin3-oxoacyl-[acyl-carrier-protein] synthase 2target
PractololBeta-1 adrenergic receptortarget
PractololCytochrome P450 2D6enzyme
PrilocaineSodium channel protein type 5 subunit alphatarget
PrilocaineVoltage-gated sodium channel alpha subunittarget
PropacetamolUDP-glucuronosyltransferase 1A6enzyme
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolUDP-glucuronosyltransferase 1A1enzyme
PropacetamolUDP-glucuronosyltransferase 1A9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 3A4enzyme
PropacetamolUDP-glucuronosyltransferase 1A10enzyme
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCannabinoid receptor 1target
PropacetamolSulfotransferase 1A1enzyme
PropacetamolProstaglandin G/H synthase 2target
PropacetamolProstaglandin G/H synthase 1target
PropacetamolCholinesteraseenzyme
PropacetamolSulfotransferase 1A3enzyme
PropacetamolSulfotransferase 1E1enzyme
PropacetamolSulfotransferase 2A1enzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
RafoxanideSerine/threonine-protein kinase OSR1target
RafoxanideSTE20/SPS1-related proline-alanine-rich protein kinasetarget
RafoxanideCyclin-dependent kinase 4target
RafoxanideCyclin-dependent kinase 6target
RafoxanideNon-selective voltage-gated ion channel VDAC1target
Rafoxanide60 kDa heat shock protein, mitochondrialtarget
RefametinibDual specificity mitogen-activated protein kinase kinase 1target
RefametinibDual specificity mitogen-activated protein kinase kinase 2target
RobenacoxibProstaglandin G/H synthase 2target
RopivacaineCytochrome P450 1A2enzyme
RopivacaineCytochrome P450 2B6enzyme
RopivacaineCytochrome P450 3A4enzyme
RopivacaineSodium channel protein type 10 subunit alphatarget
RopivacaineAlpha-1-acid glycoprotein 1carrier
RopivacaineVoltage-gated sodium channel alpha subunittarget
S-23Androgen receptortarget
SalicylanilideEpidermal growth factor receptortarget
SalicylanilideAlbumincarrier
SemapimodRAF proto-oncogene serine/threonine-protein kinasetarget
SemapimodMitogen-activated protein kinase 14target
Silver sulfadiazineDihydropteroate synthasetarget
Silver sulfadiazineDNAtarget
SitravatinibHepatocyte growth factor receptortarget
SitravatinibVascular endothelial growth factor receptor 3target
SitravatinibVascular endothelial growth factor receptor 2target
SitravatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
SulfacetamideFolic acid synthesis protein FOL1target
SulfacetamideDihydropteroate synthase type-1target
SulfacetamideDihydropteroate synthasetarget
SulfacytineDihydropteroate synthasetarget
SulfadiazineCytochrome P450 3A4enzyme
SulfadiazineCytochrome P450 2C8enzyme
Sulfadiazinedihydropteroate synthasetarget
SulfadiazineCytochrome P450 2C9enzyme
SulfadiazineDihydropteroate synthasetarget
SulfadimethoxineAlbumincarrier
SulfadimethoxineCytochrome P450 2C9enzyme
SulfadimethoxineDihydropteroate synthasetarget
SulfadoxineAmine oxidase [flavin-containing] Btarget
SulfadoxineDihydropteroate synthasetarget
SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
Sulfadoxinedihydropteroate synthasetarget
SulfaguanidineDihydropteroate synthasetarget
SulfaisodimidineProtein argonaute-2target
SulfamerazineAlbumincarrier
SulfamerazineDihydropteroate synthasetarget
SulfameterDihydropteroate synthasetarget
SulfamethazineArylamine N-acetyltransferaseenzyme
SulfamethazineAlbumincarrier
SulfamethazineDihydropteroate synthasetarget
SulfamethizoleCytochrome P450 2C9enzyme
SulfamethizoleAlbumincarrier
SulfamethizoleDihydropteroate synthasetarget
SulfamethoxazoleCytochrome P450 2C9enzyme
SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
SulfamethoxazoleDihydropteroate synthasetarget
SulfamethoxazoleCytochrome P450 3A4enzyme
SulfamethoxazoleBile salt export pumptransporter
SulfamethoxazoleAlbumincarrier
SulfamethoxypyridazineDihydropteroate synthasetarget
Sulfametopyrazinedihydropteroate synthasetarget
SulfametopyrazineDihydropteroate synthasetarget
SulfamoxoleCytochrome P450 2C9enzyme
Sulfamoxoledihydropteroate synthasetarget
SulfanilamideDihydropteroate synthasetarget
SulfanitranATP-binding cassette sub-family C member 2transporter
SulfaphenazoleCytochrome P450 2C9enzyme
SulfaphenazoleCytochrome P450 2B6enzyme
SulfaphenazoleCytochrome P450 2C9target
SulfaphenazoleDihydropteroate synthasetarget
SulfaphenazoleCytochrome P450 2D6enzyme
SulfaphenazoleCytochrome P450 2C8enzyme
SulfapyridineDihydropteroate synthasetarget
SulfapyridineDihydropteroate synthase type-1target
SulfapyridineCytochrome P450 2C9enzyme
Sulfathiazoledihydropteroate synthasetarget
SulfathiazoleAromataseenzyme
SulfathiazoleDihydropteroate synthasetarget
SulfisoxazoleDihydropteroate synthasetarget
SulfisoxazoleCytochrome P450 2C9enzyme
TacedinalineHistone deacetylasetarget
TacedinalineHistone deacetylase 1target
TefinostatHistone deacetylasetarget
TefinostatLiver carboxylesterase 1enzyme
Teriflunomide3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
TeriflunomideBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
TeriflunomideCytochrome P450 2C8enzyme
TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
TeriflunomideCytochrome P450 1A2enzyme
TocainideSodium channel protein type 5 subunit alphatarget
TocainideAlbumincarrier
TocainideCytochrome P450 1A2enzyme
TocainideVoltage-gated sodium channel alpha subunittarget
TriclocarbanCytochrome P450 1B1enzyme
TriclocarbanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
TriclocarbanCytochrome P450 1A1enzyme
VismodegibAlpha-1-acid glycoprotein 1carrier
VismodegibAlbumincarrier
VismodegibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
VismodegibCytochrome P450 2C19enzyme
VismodegibCytochrome P450 2C8enzyme
VismodegibATP-dependent translocase ABCB1transporter
VismodegibCytochrome P450 3A4enzyme
VismodegibCytochrome P450 2C9enzyme
VismodegibProtein smoothenedtarget
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylasetarget
VorinostatHistone deacetylase 8target
VorinostatProtein deacetylase HDAC6target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 2target
ZapnometinibMitogen-activated protein kinase kinase (MAPKK)target
ZapnometinibDual specificity mitogen-activated protein kinase kinase 2target