Ocular Hypertension (DBCOND0074237)

Identifiers

Synonyms
Ocular Hypertension (OH) / OHT - Ocular Hypertension / Hypertension Ocular / Ocular Hypertension (OHT) / Intraocular pressure high / Hypertension, Ocular / Ocular Hypertensive / Intraocular hypertension / Intra Ocular Hypertension / Ocular hypertension / Ocular hypertension (disorder) / Intraocular pressure increased / Intraocular pressure raised / Raised intraocular pressure (finding) / IOP increased / Raised IOP / Ocular tension increased / Tension ocular increased / Pressure intraocular increased / Increased intraocular pressure

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Apraclonidine
An alpha adrenergic agonist used to treat raised intraocular pressure.
Betaxolol
A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Bimatoprost
A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
Brimonidine
An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea.
Brinzolamide
A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Carteolol
A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
Dorzolamide
A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
Glycerin
It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
Latanoprost
An isopropyl ester prodrug used to treat increased intraocular pressure.
Levobunolol
A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Metipranolol
A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Netarsudil
A rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension.
Omidenepag isopropyl
An agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure.
Pilocarpine
A muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma.
Ripasudil
A rho kinase inhibitor indicated to treat ocular hypertension and open-angle glaucoma.
Tafluprost
An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Timolol
A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
Travoprost
A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension.
Unoprostone
A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02143843
An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Producttreatment2completed
NCT02792803
A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucomatreatment4unknown_status
NCT01162603
Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP)treatment4completed
NCT01126203
Randomized Prospective Study of Selective Laser Trabeculoplasty (SLT) Versus Argon Trabeculoplasty (ALT) in Patients With Pseudoexfoliation Glaucoma and Ocular HypertensionNo drug interventionstreatment3completed
NCT00465803
A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertensiontreatment3completed
NCT00928590
Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT04944290
To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyestreatment3completed
NCT00950690
Efficacy and Tolerability of Xalatan in PatientsNot AvailableNot Availablecompleted
NCT00283764
Safety And Efficacy Of Xalatan Delivered Using Either A Conventional Dropper Bottle or A Delivery Devicetreatment3withdrawn
NCT01699464
A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Monthstreatment2completed
NCT01943721
A Study of the VISION5 Product in Patients With Glaucoma or Ocular HypertensionNo drug interventionsprevention1completed
NCT00465621
Dose Response Study of AL-37807 Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00838721
Evaluation of Pascal Laser TrabeculoplatyNo drug interventionstreatmentNot Availablecompleted
NCT00821002
A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)treatment2completed
NCT04433702
Effect of Negative Pressure on Pattern Electroretinography ReadingsNo drug interventionspreventionNot Availablewithdrawn
NCT02339584
Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)treatment3completed
NCT02858284
Evaluation of Safety and Efficacy of TUG (Therapeutic Ultrasound for Glaucoma) in the Treatment of Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatmentNot Availableterminated
NCT05039684
Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical ProstaglandinsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05844384
Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority TrialNo drug interventionsotherNot Availablerecruiting
NCT00300079
Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertensiontreatment4completed
NCT01330979
24-hour Efficacy of AR-12286No drug interventionstreatment2completed
NCT00657579
Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular HypertensionNo drug interventionsNot Available2completed
NCT04005079
Pilocarpine After Combined Cataract/Trabectome Surgerytreatment3withdrawn
NCT03927443
A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertensiontreatment3withdrawn
NCT00293787
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01528787
Study of AR-13324 in Patients With Elevated Intraocular Pressuretreatment2completed
NCT02507687
Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01312454
Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412Ctreatment2terminated
NCT00912054
DuoTrav APS Versus XALACOM® in Ocular Surface Healthtreatment3terminated
NCT00047554
Study of TRAVATAN in Subjects With Iris Pigmentation ChangesNot AvailableNot Availableterminated
NCT06266351
EVALUATION OF CATS TONOMETER PRISM IN LASIK SUBJECTSNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01646151
A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular HypertensionNot AvailableNot Availablecompleted
NCT00288951
Phase III Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension PatientsNo drug interventionstreatment3completed
NCT00159653
A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucomatreatment3completed
NCT00330577
24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patientstreatment4completed
NCT02003547
A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjectstreatment1completed
NCT02390245
Philadelphia Telemedicine Glaucoma Detection and Follow-Up StudyNo drug interventionsotherNot Availablecompleted
NCT01510145
Efficacy of Changing to TRAVATAN® From Prior Therapytreatment4completed
NCT00698945
Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG)treatment4completed
NCT04609345
Prevalence of Ocular Surface Disease in Malaysian Glaucoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00803998
Ocular Hypertension Treatment Study (OHTS)No drug interventionsNot AvailableNot Availablecompleted
NCT04761705
Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2suspended
NCT02471105
Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/mltreatment4unknown_status
NCT01279083
Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT04742283
Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00652483
Safety and Efficacy Study of Brimonidine in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01206361
Real World Data Study Assessing The Persistency Of Xalacom And The Other Fixed Dose Combination Products, Duotrav And Ganfort, In The United KingdomNot AvailableNot Availablecompleted
NCT00293761
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT06152861
Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertensiontreatment2recruiting
NCT00047528
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41No drug interventionstreatment3completed
NCT04654611
Tafluprost Preservative Free Switch Studytreatment4completed
NCT00967811
A Study of Different Formulations of the L-PPDS in Subjects With OH or OAGNo drug interventionstreatment2completed
NCT00047593
Phase 3 Study Comparing IOP Lowering in OAG or OH in Japanese Subjects C-01-98No drug interventionstreatment3completed
NCT00347893
The Efficacy of Selective Laser TrabeculoplastyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04024293
Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus TonometryNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT00834171
A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/TobramycinNot AvailableNot Availablecompleted
NCT02730871
Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®treatment4terminated
NCT01062971
Clinical Study of A Fixed Combination of Timolol-Brimonidine-Dorzolamidetreatment2completed
NCT01369771
The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucomatreatment4completed
NCT06177678
A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment2not_yet_recruiting
NCT01779778
Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion PressureNo drug interventionsNot AvailableNot Availablecompleted
NCT01628588
Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT02108288
Pharmacokinetic Study of OPC-1085EL Ophthalmic Solution in Healthy Male Adult VolunteersNot Available1completed
NCT01410188
Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT00675207
Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogstreatment4completed
NCT01452009
Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004%treatment3withdrawn
NCT00761709
Safety and Intraocular Pressure (IOP)-Lowering Efficacy of AL-39256 in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00430209
Neurovascular Coupling in Eyes of Glaucoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00620256
Adjunctive Study of AL-37807 Ophthalmic Suspensiontreatment2completed
NCT01886456
IOP Lowering Effect of PLT Versus SLT in Naiv OAG PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT01853085
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical ReasonsNot AvailableNot Availablecompleted
NCT05273385
Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With GlaucomaNo drug interventionshealth_services_researchNot Availablerecruiting
NCT02105285
Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertensiontreatment3completed
NCT02537015
An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Inserttreatment2completed
NCT01693315
Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucomatreatment2completed
NCT00047515
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-69No drug interventionstreatment3completed
NCT03067415
Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Dailytreatment2unknown_status
NCT01510132
Travacom Post Marketing Surveillance Studytreatment4withdrawn
NCT01987752
Safety and Efficacy of Combigan® Ophthalmic Solution in KoreaNot AvailableNot Availablecompleted
NCT00781300
Intraocular Pressure With Loteprednol and Dexamethasonetreatment4completed
NCT01298700
Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment4completed
NCT00293800
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01978600
Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00798759
Examination of Ocular Surface Effects With Administration of Travatan Z and XALATANtreatment4completed
NCT02617459
Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00332059
Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT03419975
A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patientstreatment3completed
NCT02057575
Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressuretreatment2completed
NCT01594970
A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH)treatment4completed
NCT01254370
Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Diseasetreatment2completed
NCT00716742
Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG)Not AvailableNot Availablecompleted
NCT01864642
Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect SubjectsNo drug interventionstreatmentNot Availablecompleted
NCT00051142
A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)treatment3completed
NCT00061542
Safety and Efficacy Study of BETOPTIC S 0.25% and Timolol Gel-forming Solution 0.25% and 0.5% in Pediatric Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00638742
A Phase 1, Open-Label Study of Latanoprost Acid Plasma Concentrations in Pediatric and Adult Glaucoma Patients Treated With Latanoprost.other1completed
NCT02014142
A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT01217606
Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00047606
Phase 4 Study Comparing IOP Lowering in OAG or OH in Caucasian or Japanese Subjects C-02-32No drug interventionstreatment4terminated
NCT00828906
DuoTrav® Eye Drops As Replacement Therapy Programtreatment4completed
NCT01927406
The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.prevention4withdrawn
NCT00140049
A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucomatreatment4completed
NCT00735449
Comparing Efficacy and Safety of Combigan With Timolol Adjunctive to Xalatan in Glaucoma or Ocular Hypertension Subjectstreatment4completed
NCT02742649
A Study to Evaluate Efficacy and Safety of a Fixed Combination Ocular Insert in Participants With Open-angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT01789736
A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Daystreatment2completed
NCT01979913
An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in Patients With Ocular Hypertension or Primary Open Angle Glaucoma With an Uncontrolled Intraocular Pressure of 30 mmHg and Moretreatment4completed
NCT01265719
Long-Term Non-Interventional Latanoprost StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05333419
Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension.treatment1completed
NCT00429819
Neurovascular Coupling in Eyes of Glaucoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01361841
Effects of Latanoprost, Bimatoprost and Travoprost in Patients With Latanoprost-resistant GlaucomatreatmentNot Availableunknown_status
NCT01833741
A Study of LUMIGAN® RC in the Clinical Settingtreatment4completed
NCT00440141
Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%treatment4completed
NCT00788541
A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertensionprevention2terminated
NCT00047541
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70No drug interventionstreatment3completed
NCT01864317
Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor ImagingNo drug interventionsbasic_science2terminated
NCT00108017
Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED)treatment3completed
NCT02801617
Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertensiontreatment3terminated
NCT02003534
A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4completed
NCT00515424
Tolerability, Safety and Efficacy of RKI983 Eye Drops in Subjects With Primary Open Angle Glaucoma and Ocular HypertensionNo drug interventionstreatment1completed
NCT04947124
A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101No drug interventionstreatment2completed
NCT01976624
Safety and Efficacy of Bimatoprost/Timolol (Ganfort®) Ophthalmic Solution in KoreaNot AvailableNot Availablecompleted
NCT04524416
MINIject Global Long-Term Follow-up StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05279716
Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyltreatment4unknown_status
NCT01520116
Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertensiontreatment1 / 2unknown_status
NCT00652496
Safety and Efficacy Study of Different Formulations of Bimatoprost Once-Daily in Patients With Glaucoma or Ocular Hypertensiontreatment2completed
NCT02295358
The Effect of Omega-3 Fatty Acid Supplementation on Intraocular Pressure & Ocular SurfaceNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03584958
Comparing Refractive and Visual Outcomes of MIGS and Traditional SurgeriesNo drug interventionsNot AvailableNot Availableunknown_status
NCT00621335
A Investigator Masked Parallel Comparison of Tolerability of Combigan and CosoptNo drug interventionsNot AvailableNot Availablecompleted
NCT03395535
Laser-1st vs Drops-1st for Glaucoma and Ocular HypertensionNo drug interventionstreatment4completed
NCT00168363
Safety and Efficacy of Brimonidine in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00230763
Determination Of Predictive Factors Allowing To An Additional 10% Reduction Of Intra-Ocular Pressuretreatment3completed
NCT01215786
Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucomatreatment1completed
NCT02030886
IOP Patterns in Ocular Hypertensive Patients Newly Converted to Glaucoma vs Stable Ocular Hypertensive PatientsNo drug interventionsotherNot Availableterminated
NCT05248139
Safety and Effectiveness of Drop-free Small Incision Cataract SurgerytreatmentNot Availableunknown_status
NCT01664039
An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN®treatment4completed
NCT01033422
Safety and Efficacy of Daily CF101 Administered Orally in Subjects With Elevated Intraocular Pressuretreatment2completed
NCT00856622
A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patientstreatment3completed
NCT05335122
A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)treatment2active_not_recruiting
NCT00941525
Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressurebasic_science4completed
NCT00333125
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01749930
Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00637130
Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprosttreatment2completed
NCT01999348
A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical SettingNot AvailableNot Availablecompleted
NCT04499248
AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1 / 2recruiting
NCT00804648
Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00809848
Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle Glaucomatreatment1 / 2completed
NCT00539526
Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analoguestreatment4completed
NCT03192826
Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomyprevention4completed
NCT01284166
Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3withdrawn
NCT00744666
IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroidsscreening4unknown_status
NCT04863365
A Study of Efficacy and Safety of PHP-201 in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment3unknown_status
NCT04360174
CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1completed
NCT04500574
Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertensiontreatment1recruiting
NCT00824720
Safety and Efficacy of a Glaucoma Drug Delivery SystemNo drug interventionstreatment2completed
NCT01281020
Adherence With Fixed Versus Unfixed Glaucoma TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT04401982
Measuring the Effects of Rhopressa on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma SuspectsNot AvailableNot Availablecompleted
NCT02165631
The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion PressureNo drug interventionsNot AvailableNot Availablecompleted
NCT05043831
Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population The Zhuiguang TrialNo drug interventionstreatmentNot Availablewithdrawn
NCT01026831
Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)treatment3completed
NCT00815373
The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG)Not AvailableNot Availablewithdrawn
NCT06394973
Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertensiontreatment2recruiting
NCT01493427
Efficacy of Changing to TRAVATAN® From Prior Therapytreatment4completed
NCT04595227
Glaucoma Screening Using Dynamic Analysis of Computerized Pupillary Light Reflex Assessment DeviceNo drug interventionsNot AvailableNot Availableunknown_status
NCT00751127
A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02348476
A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular HypertensionNo drug interventionsNot AvailableNot Availablecompleted
NCT02140060
6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02796560
Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT05159960
Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat TrialNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT00767494
Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPTtreatment3terminated
NCT00690794
Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00051194
A 6-week Safety & Efficacy Study of Combination Intraocular Pressure-lowering Therapy in Patients With Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT03529591
Is the Reduction in IOP After Treatment of 180 Degrees Equivalent to Treatment of 360 Degrees With SLT?No drug interventionstreatmentNot Availablecompleted
NCT02003391
Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressuretreatment4completed
NCT02207491
Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01016691
Safety and Efficacy of a Drug Delivery System in Glaucomatreatment2completed
NCT01227291
SYL040012. Tolerance and Effect on Intraocular Pressure in Subjects With Intraocular Pressure (IOP) >= 21 mm Hgtreatment1 / 2completed
NCT00596791
Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Dropstreatment3completed
NCT01781962
A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular HypertensionNo drug interventionsNot AvailableNot Availableterminated
NCT01229462
Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensiontreatmentNot Availablecompleted
NCT00892762
Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Healthtreatment3completed
NCT02743780
A Three Part Study of MGV354 in Ocular Hypertension or GlaucomaNo drug interventionsother1 / 2completed
NCT03825380
Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous Patientstreatment3completed
NCT00471380
A Phase IV Study of Travoprost + Brinzolamide to Treat Glaucoma or Ocular Hypertensiontreatment4completed
NCT04285580
A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00061529
A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01936389
A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or GlaucomaNo drug interventionstreatment2completed
NCT00311389
A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00934089
A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329treatment2completed
NCT04702789
Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension.treatment4terminated
NCT00527592
A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT02312544
Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01739244
Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucomatreatment2completed
NCT02136940
Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01467440
Efficacy of Selective Laser Trabeculoplasty in Patients Under Treatment With Topical ProstaglandinesNo drug interventionsNot AvailableNot Availableunknown_status
NCT01830140
A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00656240
To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular HypertensionNo drug interventionsNot Available2completed
NCT00332540
Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00800267
A Study of Glaucoma or Ocular Hypertension in Patients Within the United Statestreatment3completed
NCT00150267
A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertensiontreatment3completed
NCT01426867
A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2%treatment2completed
NCT00595101
A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.treatment2completed
NCT00683501
Safety, Efficacy, and Pharmacokinetic Profile of DNB-001 in Subjects With Elevated Intraocular Pressuretreatment1 / 2completed
NCT00527501
IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01628601
GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to MonotherapyNot AvailableNot Availablecompleted
NCT02247804
Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01309204
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02384772
Survey of Patients Taking IOP-Lowering Eye DropsNo drug interventionsNot AvailableNot Availablecompleted
NCT00862472
Safety and Efficacy Study of DuoTrav APS Versus DuoTravtreatment3withdrawn
NCT02105272
Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertensiontreatment3completed
NCT04024072
To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyestreatment3completed
NCT00471068
Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment4terminated
NCT05495269
Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP)No drug interventionstreatment2completed
NCT03318146
Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LPtreatmentNot Availableunknown_status
NCT05181046
Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02874846
Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solutiontreatment2completed
NCT03891446
Long-term Safety and Efficacy Extension Trial of Bimatoprost SRtreatment3enrolling_by_invitation
NCT02571712
Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00651612
Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension Patientstreatment3completed
NCT01937312
Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analoguetreatment4completed
NCT00051181
A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucomatreatment3completed
NCT01707381
BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00761995
Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT04972695
Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc ImagesNo drug interventionsNot AvailableNot Availablecompleted
NCT01001195
Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solutiontreatment2completed
NCT01168414
A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT04647214
18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)No drug interventionsNot AvailableNot Availablecompleted
NCT01975714
Intraocular Pressure and Tolerability Study of Preservative-free Prostaglandins (Bimatoprost and Latanoprost) on Glaucoma and Ocular Hypertension: European, Multicentric, Investigator-led, Single Masked Studytreatment4completed
NCT02967614
KJ-TFC-004 Drug-drug Interaction Studytreatment1completed
NCT00572455
Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.treatment2completed
NCT00822055
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT01453855
Travoprost 3-Month Safety and Efficacy Studytreatment3completed
NCT00051155
A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT)treatment3completed
NCT02434250
Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser TrabeculectomyNo drug interventionstreatmentNot Availablecompleted
NCT02102750
A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertensiontreatment1completed
NCT01632423
A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT04448223
A Clinical Study to Evaluate the Efficacy and Safety of CKD-351treatment2unknown_status
NCT02628223
180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT02623023
Prophylaxis for Anti-VEGF-induced IOP ElevationpreventionNot Availablewithdrawn
NCT02419508
SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)treatment4completed
NCT01291108
Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02379208
Evaluation of Rate of Progression With Perimetry in Newly Diagnosed Open Angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01568008
Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT01191008
Long Term Use Of Xalacom In Patients Glaucoma Or Ocular HypertensionNot AvailableNot Availablecompleted
NCT00650338
Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00476138
Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early Glaucomasupportive_care1 / 2unknown_status
NCT00823043
A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With 2 DrugsNot AvailableNot Availablecompleted
NCT06441643
Next Generation Rocklatantreatment2not_yet_recruiting
NCT01216943
Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00061503
Mechanism of Action of TRAVATAN 0.004% in Subjects With Glaucoma or Ocular Hypertensiontreatment4completed
NCT02839590
Aqueous Dynamics and Glaucoma SurgeriesNo drug interventionsNot AvailableNot Availableunknown_status
NCT01111890
Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertensiontreatment4completed
NCT04442464
Intraocular Pressure in Ocular Hypertensives With Scleral Lens WearNo drug interventionsotherNot Availableterminated
NCT00811564
An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension Subjectstreatment4completed
NCT02246764
Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01157364
Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertensiontreatment1 / 2completed
NCT01028664
Use of an Ocular Telemetry Sensor in Diamox Treated PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT00545064
Dry Eye Study With Cosopt® Over 8 Weeks in Patients With Open-Angle Glaucoma or Ocular Hypertension (0507A-152)(COMPLETED)treatment4completed
NCT01068964
Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular HypertensiontreatmentNot Availablecompleted
NCT02207621
Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertensiontreatment3completed
NCT00287521
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00650702
Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01731002
Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressuretreatment2completed
NCT01253902
Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT01084902
Efficacy Comparison of Xalatan and Azopt on POAG and OHtreatmentNot Availableunknown_status
NCT01170884
Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan®treatment4completed
NCT00332384
Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT04140279
A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertensiontreatment4withdrawn
NCT01298687
Divided Dose of TRAVATAN®treatment2completed
NCT00803387
Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without PreservativeNot AvailableNot Availablecompleted
NCT03204487
A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thicknesstreatment4completed
NCT04911387
iCare® Home vs Goldmann Applanation TonometryNo drug interventionsNot AvailableNot Availablecompleted
NCT00670033
Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02674854
Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT03201354
Efficacy and Safety of the ExPRESS Implant Versus Deep Sclerectomy in Combined SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT02250651
Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00872651
Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01863953
A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular Hypertensiontreatment2completed
NCT03284853
Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01310777
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00121147
Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to TravatantreatmentNot Availablecompleted
NCT01012245
Non-Interventional Study In Patients With Ocular Hypertension And Open Angle Glaucoma Treated With Xalatan And XalacomNo drug interventionsNot AvailableNot Availablecompleted
NCT03844945
Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japantreatment2completed
NCT02993445
Effect of Alternate Therapies on Intraocular Pressure in Ocular HypertensionNo drug interventionstreatmentNot Availablecompleted
NCT04405245
Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucomatreatment2completed
NCT00332345
Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertensiontreatment2completed
NCT01177098
Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01547598
Safety and Efficacy of LUMIGAN® RC Versus DuoTrav® in Patients Who Require Further Intraocular Pressure (IOP) Reductiontreatment4completed
NCT00277498
A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucomatreatment3completed
NCT00672997
A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT06572397
Open-Label Study of Safety of H1337 in Healthy VolunteersNo drug interventionstreatment1not_yet_recruiting
NCT04830397
Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).treatment2completed
NCT01696383
Assessing the Efficacy of DuoTrav as a Replacement Therapy in Glaucoma Patients in Russiatreatment4withdrawn
NCT00847483
Comparison of Latanoprost With Travoprost and Bimatoprost in Patients With Elevated IOP. A 12-weeks, Masked Evaluator, Phase IV Multi-center Study in the UStreatment4completed
NCT00441883
Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucomatreatment2completed
NCT06455683
The A D A G I O StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02061683
A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4completed
NCT01814761
A Study of Bimatoprost 0.01% in the Clinical SettingNot AvailableNot Availablecompleted
NCT01306461
Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrationstreatment3completed
NCT00947661
Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT00001161
Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and LensNo drug interventionsNot AvailableNot Availablecompleted
NCT01528111
Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT00567411
Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser TrabeculoplastytreatmentNot Availableunknown_status
NCT00440011
Bimatoprost 0.03% Versus Travoprost 0.004% in Patients Currently on Latanoprost 0.005%treatment4completed
NCT00402493
Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma DropstreatmentNot Availablecompleted
NCT01114893
Travoprost Five Day Posology Studytreatment2completed
NCT05299593
24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration.supportive_care4unknown_status
NCT01087671
Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Dropstreatment3completed
NCT01261871
Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg PositioningNo drug interventionsNot AvailableNot Availablecompleted
NCT00314171
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02059278
Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT04891588
Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSDtreatmentNot Availableunknown_status
NCT01446588
Ocular Hypertension And Yoga StudyNo drug interventionstreatmentNot Availablewithdrawn
NCT03808688
Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Settingtreatment4completed
NCT01467388
Efficacy of Selective Laser Trabeculoplasty in Pseudophakic PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01721707
Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OHtreatment3withdrawn
NCT02989909
Clinical Evaluation of CATS Tonometer PrismNo drug interventionsdiagnosticNot Availablecompleted
NCT01719809
An Evaluation of the Ability to Train Established Glaucoma Patients Who Have Difficulty in Drop InstillationNo drug interventionsNot AvailableNot Availableterminated
NCT02914509
Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHTtreatment3completed
NCT01123785
A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucomatreatment1 / 2completed
NCT00304785
Latanoprost Versus Fotiltreatment4completed
NCT00804115
The International Collaborative Exfoliation Syndrome Treatment StudytreatmentNot Availableunknown_status
NCT00676637
Glaucoma Adherence StudyNot AvailableNot Availablecompleted
NCT06582732
Performance of the Travoprost Intraocular Implanttreatment2completed
NCT03235232
BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertensiontreatment3completed
NCT05913232
Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment2active_not_recruiting
NCT00486252
Non Interventional Study in Patients With Open Angle Glaucoma and/or Ocular Hypertension Treated With XALATAN®No drug interventionsNot AvailableNot Availablecompleted
NCT00001152
Pigment Dispersion Syndrome With and Without GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04585100
FM101 Safety, Tolerability, Efficacy Study in the Patients With Ocular HypertensionNo drug interventionstreatment1 / 2unknown_status
NCT05397600
Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patientstreatment3completed
NCT02558400
Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00820300
A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucomatreatment2completed
NCT04910100
Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertensiontreatment2completed
NCT00651859
Safety and Efficacy Study of Bimatoprost in Ethnically Japanese Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02585375
Latanoprost Preserved Versus Unpreserved: Effect on Tear Film Thickness as Measured With OCTbasic_science4unknown_status
NCT03926975
The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim WidthNo drug interventionsbasic_scienceNot Availablecompleted
NCT01540370
Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT)No drug interventionsNot AvailableNot Availablecompleted
NCT05277870
Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular HypertensionNo drug interventionssupportive_careNot Availablerecruiting
NCT01489670
Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular HypertensionNot AvailableNot Availablecompleted
NCT00541242
Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular Hypertensiontreatment4completed
NCT00576342
Patient Preference Studytreatment3completed
NCT06120842
Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solutiontreatment1 / 2recruiting
NCT00273442
Assessing Cosopt Switch Patientstreatment4completed
NCT01937299
Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z®treatment4completed
NCT00845299
Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT01327599
Efficacy of Changing to DUOTRAV® From Prior Therapytreatment4completed
NCT01110499
Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment2completed
NCT04149899
Safety and IOP-Lowering Effects of WB007treatment1 / 2completed
NCT00069706
Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patientstreatment2completed
NCT00652106
Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01302249
AR-12286 in Combination With Latanoprosttreatment2completed
NCT00961649
Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combinationtreatment2terminated
NCT00751049
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdomtreatment3completed
NCT01037036
A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAGtreatment2completed
NCT00332436
Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT00848536
Efficacy Study of Travoprost APS Versus TRAVATANtreatment3completed
NCT01995136
Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucomatreatment4completed
NCT03257813
Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)treatment3completed
NCT02394613
A Phase I Clinical Trial of DARCNo drug interventionsdiagnostic1unknown_status
NCT06144918
Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressuretreatment2completed
NCT02325518
Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic SolutionNot Available4completed
NCT06061718
Travoprost Intraocular Implant in Conjunction With Cataract Surgerytreatment3active_not_recruiting
NCT00069719
Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension PatientsNo drug interventionstreatment2completed
NCT04445519
Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00383019
A Study Comparing Xalacom And Xalatan In Patients With Primary Open Angle Glaucoma (POAG) Or Ocular Hypertension (OH).treatment3completed
NCT00761319
Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Healthtreatment3completed
NCT02097719
Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertensiontreatment4completed
NCT00855517
A Phase 2 Study of the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucomatreatment2withdrawn
NCT00878917
Equivalence Study of Dorzolamide 2% Eye Drops Solutiontreatment3completed
NCT01297517
Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%treatment3completed
NCT02891317
Assessing Ocular Hemodynamic Response to Surgical Intervention in GlaucomaNo drug interventionsNot AvailableNot Availableterminated
NCT01464424
Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular Hypertension Treated With Travoprost 0.004% (TRAVATAN® Z) or Bimatoprost 0.01% (LUMIGAN®)treatment4completed
NCT03868124
Clinical Study Comparing Two Models of a Travoprost Intraocular Implanttreatment3active_not_recruiting
NCT05456724
A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1 / 2active_not_recruiting
NCT02863224
Advanced Glycation End Products as a Biomarker for Accelerated AgeingNo drug interventionsNot AvailableNot Availablecompleted
NCT01668524
ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) SubjectsNo drug interventionstreatment2completed
NCT00443924
Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or GlaucomaNo drug interventionstreatment1completed
NCT00061516
Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT02710916
SD-OCT Multimodal Analysis in GLaucomaNo drug interventionsdiagnosticNot Availablecompleted
NCT01357616
Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00219596
Xalacom And Combination Of Unfixed Latanoprost And Timolol In Subjects With Open-Angle Glaucoma Or Ocular Hypertensiontreatment3completed
NCT00825396
An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular HypertensionNo drug interventionstreatmentNot Availablecompleted
NCT00424996
Utility of Heidelberg Retina Tomograph in Monitoring Glaucoma ProgressionNo drug interventionsNot AvailableNot Availablecompleted
NCT00941096
Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combinationtreatment4completed
NCT01655758
24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertensiontreatment4completed
NCT00945958
Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT00314158
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01474135
AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressuretreatment2completed
NCT04620135
Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02167035
Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID)treatment4completed
NCT01210963
Central Corneal Thickness With SENSIMED TriggerfishNo drug interventionsNot AvailableNot Availablecompleted
NCT03519386
Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%treatment3active_not_recruiting
NCT00546286
A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153)treatment3completed
NCT01271686
24-hour IOP-lowering Effect of 0.01% Bimatoprosttreatment4completed
NCT00759239
Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed Dose Combination of Travoprost 0.004% / Timolol Maleate 0.5% in Patients With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT01658839
Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patientstreatment1completed
NCT04035239
Retinal Effects of Balance Goggles System in Glaucoma Balance Goggles System (BGS) in Patients With GlaucomaNo drug interventionstreatment1completed
NCT00760539
Safety and Efficacy of Travoprost/Timolol BAC-freetreatment3completed
NCT04743622
Comparison of Efficacy and Ocular Surface Disease Assessment Between Monoprost and BAK-preserved Latanoprosttreatment4completed
NCT00708422
Effects of Travatan Z and Xalatan on Ocular Surface Healthtreatment4completed
NCT04335825
Surgical and Refractive Outcomes of Combined Glaucoma SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT00000125
Ocular Hypertension Treatment Study (OHTS)No drug interventionsprevention3completed
NCT02047630
Efficacy of the Brand-name Latanoprost and One of Its Generic Version in Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4terminated
NCT03870230
Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy SubjectsNo drug interventionsbasic_scienceNot Availableunknown_status
NCT05401357
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.treatment3unknown_status
NCT01881126
An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertensiontreatment4completed
NCT03960866
Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucomatreatment2completed
NCT03928665
Long-term Observation of Ophthalmic Changes in Patients With Obstructive Sleep ApneaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02558374
Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertensiontreatment3completed
NCT06267274
A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyestreatment1recruiting
NCT01099774
Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01297920
Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%treatment3completed
NCT01229982
A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT03534882
Effects of Prostaglandin Analogue Washout Following Long-term Therapy in Adults With Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT03850782
Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertensiontreatment3active_not_recruiting
NCT00372931
A Phase II Study of AL-37807 to Treat Open-Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT01525173
A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular Hypertensiontreatment4completed
NCT01092273
Bimatoprost Versus Travoprost at Cairo UniversityNo drug interventionsNot AvailableNot Availablecompleted
NCT02129673
A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT02017327
Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dosetreatment4completed
NCT00372827
Study of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00503360
Tolerability, Safety and Efficacy of SAD448 in Subjects With Ocular HypertensionNo drug interventionstreatment1completed
NCT01292460
Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against MonotherapiesNo drug interventionstreatment3completed
NCT01342094
DE-111 Against Timolol Ophthalmic Solution 0.5%treatment3completed
NCT00868894
Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT00347191
Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments.No drug interventionsNot AvailableNot Availablecompleted
NCT04202562
Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual BladeNo drug interventionstreatmentNot Availablecompleted
NCT00140062
Efficacy And Safety Of Xalatan Compared To Usual Care In Patients With Open Angle Glaucoma Or Ocular Hypertension.treatment4completed
NCT00751062
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinaviatreatment3completed
NCT02338362
Inhaled Corticosteroids: Effect on Intraocular Pressure in Patients With Controlled Glaucomaother4completed
NCT01896180
Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprosttreatment2completed
NCT00273429
Cosopt Versus Xalatantreatment4completed
NCT00887029
A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucomatreatment4completed
NCT04957329
Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cellstreatment4recruiting
NCT00143429
Corneal Versus Conjunctival Delivery Using a Delivery Devicetreatment2withdrawn
NCT00680329
Glaucoma Adherence Study, SpainNot AvailableNot Availablecompleted
NCT03450629
Evaluation of Safety and Efficacy of PDP-716treatment3completed
NCT02083289
A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)treatment2completed
NCT00846989
Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertensiontreatment1 / 2completed
NCT03293992
A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment1completed
NCT00326092
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01379144
A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertensiontreatment2completed
NCT01263444
Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapytreatment4completed
NCT01915940
Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertensiontreatment2completed
NCT06498440
Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCTtreatment4not_yet_recruiting
NCT01241240
Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT05389267
Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients.No drug interventionstreatment1 / 2active_not_recruiting
NCT01491867
Continuous Intraocular Pressure (IOP) Measurement and Ability to Detect Treatment EffectdiagnosticNot Availablecompleted
NCT05857267
Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safetytreatment4recruiting
NCT03131167
Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle GlaucomaNo drug interventionstreatment1completed
NCT01415401
Efficacy and Tolerability of AZARGA® as Replacement Therapy in Patients on COMBIGAN® Therapy in Canadatreatment4completed
NCT00647101
A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucomatreatment4completed
NCT03750201
A Study to Assess an Automated Laser Device for Direct Selective Laser TrabeculoplastyNo drug interventionstreatmentNot Availablecompleted
NCT00538304
A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular Hypertensiontreatment2completed
NCT01254604
Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)treatment3completed
NCT01749904
Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT05022004
A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01895972
Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024% in Japanese Subjects With OAG or OHTtreatment3completed
NCT00332072
Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients Wtih Glaucoma or Ocular Hypertensiontreatment3completed
NCT00753168
Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-Angle Glaucomatreatment1 / 2completed
NCT00051168
A Long-term Safety Study of Once-daily Travatantreatment3completed
NCT00508469
Adherence Assessment With Travalert Dosing Aidtreatment4completed
NCT03762369
A Clinical Study to Evaluate the Efficacy and Safety of CKD-351treatment3unknown_status
NCT02358369
Dose-Ranging Study of the Bimatoprost Ocular Inserttreatment2completed
NCT01637246
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to MonotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00918346
Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulationtreatment3completed
NCT02250612
SYL040012, Treatment for Open Angle Glaucomatreatment2completed
NCT02020512
A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4completed
NCT01589510
A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT00767481
1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPTtreatment3terminated
NCT00273481
Cosopt Versus Xalacomtreatment4completed
NCT00822081
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT01342081
DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%treatment3completed
NCT03901781
Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjectstreatment1completed
NCT00329095
An Evaluation of Use of Topical Ocular Hypotensive Medication by Compliancediagnostic4completed
NCT00457795
24-hour IOP-lowering Effect of Brimonidine 0.1%treatment4completed
NCT01628614
A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)No drug interventionsNot AvailableNot Availablecompleted
NCT04036214
Efficacy and Safety Outcomes of Optometrist Performed Selective Laser Trabeculoplasty (SLT)No drug interventionsNot AvailableNot Availableunknown_status
NCT04284514
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solutiontreatment1completed
NCT01735214
An Observational Study of Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) Who Switched IOP-lowering TreatmentsNo drug interventionsNot AvailableNot Availablecompleted
NCT02278614
Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patientstreatment3completed
NCT04695314
Foot Reflexology in Ocular Hypertensive and Glaucoma PatientsNo drug interventionspreventionNot Availablecompleted
NCT01340014
Patient Preference Comparison of AZARGA Versus COSOPTtreatment4completed
NCT00334750
Distribution of Risk Factors in Ocular Hypertension and Open-Angle Glaucoma Patients in CanadaNo drug interventionsNot AvailableNot Availablecompleted
NCT01430923
Clinical Evaluation of Safety and Efficacy of Refrigeration Free LatanoprosttreatmentNot Availableunknown_status
NCT03798223
Optimal Treatment Protocol for Selective Laser TrabeculoplastyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01987323
Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertensiontreatment1 / 2completed
NCT00494923
Early Diagnosis, Pathogenesis and Progression of Open Angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00143208
Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh.treatment4completed
NCT02179008
Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT04630808
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3recruiting
NCT04747808
Study of LL-BMT1 in Patients With Elevated Intraocular PressureNo drug interventionstreatment2completed
NCT05241938
PSLT Compared to Prostaglandin Analogue Eye DropsNo drug interventionstreatmentNot Availableunknown_status
NCT02623738
A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-treatment2 / 3completed
NCT00300443
Safety and Efficacy Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertensiontreatment2 / 3completed
NCT00990743
Tolerance and Effect on Intraocular Pressure After Administration of SYL040012treatment1completed
NCT01481051
A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT01481077
A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT04888156
Impact of Self-tonometry on Glaucoma Treatment Decision.No drug interventionsNot AvailableNot Availablecompleted
NCT04064918
Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual AcuityNo drug interventionsotherNot Availablewithdrawn
NCT03931317
Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual AcuityotherNot Availablecompleted
NCT04412096
Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variancetreatment4recruiting
NCT02754570
The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion PressuretreatmentNot Availablecompleted
NCT03657797
Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT03532867
Study of Changes in Retrofoveolar Choroidal Thickness During Aerobic ExerciseNo drug interventionsotherNot Availableunknown_status
NCT02300818
Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion.No drug interventionstreatment1 / 2unknown_status
NCT01917383
A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucomatreatment2completed
NCT01318252
AL-54478 Proof of Concept Studytreatment2completed
NCT02829996
Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAGtreatment2completed
NCT02565173
Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucomatreatment3completed
NCT06249152
Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT PatientsNo drug interventionstreatment2recruiting
NCT01670266
Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucomatreatment1completed
NCT02226094
Safety and Efficacy of Deep Wave Trabeculoplasty (DWT) in Primary Open Angle Glaucoma and Ocular HypertensionNo drug interventionstreatment1 / 2terminated
NCT01180062
Safety Study of Latanoprost Slow Release Inserttreatment1terminated
NCT06016972
Qlaris Phase 2 Study of QLS-111 in POAG and/or OHT PatientsNo drug interventionstreatment2active_not_recruiting
NCT04647461
Comparison of Efficacy and Ocular Surface Disease Assessment Between BRIDIN-T Eye Drops 0.15% and ALPHAGAN-P Eye Drops 0.15% in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investigator-blind, Active-control, Randomized, Multi-center Trialtreatment4unknown_status
NCT06078592
Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensivetreatment4completed
NCT01567761
The Effect of Two Different Artificial Respiration Methods on the Intraocular Pressure During Surgery Under General AnesthesiaNo drug interventionsNot AvailableNot Availableunknown_status