Ocular Hypertension, Primary Open-angle Glaucoma (POAG) (DBCOND0088544)

Identifiers

Synonyms
Primary Open- Angle Glaucoma / Primary Glaucoma, Open Angle / Primary Open-Angle Glaucoma (POAG) / Primary Open Angle Glaucoma / Primary Glaucoma Open-Angle / Glaucoma, Primary Open Angle (POAG) / Glaucoma Primary Open Angle / Glaucoma, Primary Open Angle / Primary Open Angle Glaucoma (POAG) / Primary Open-Angle Glaucoma / Glaucoma Open-Angle Primary / Primary Open-Angle Glaucoma, Ocular Hypertension / Primary Open Angle Glaucoma, Ocular Hypertension / Open-angle glaucoma / Primary open angle glaucoma (disorder) / Pigmentary glaucoma / Unspecified open-angle glaucoma / Open angle glaucoma NOS / Open angle glaucoma / Open-angle glaucoma (disorder) / Glaucoma, Open-Angle / Open-angle glaucoma, unspecified / Advanced open-angle glaucoma (disorder) / Glaucoma simplex / Pigmentary glaucoma (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Betaxolol
A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04736264
Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary GlaucomaNo drug interventionshealth_services_researchNot Availableunknown_status
NCT04454190
Development and Validation of a Model to Predict Fast Progression in GlaucomaNo drug interventionsNot AvailableNot Availableterminated
NCT04396002
Glaucoma, Visual Field Loss, and Their Association With Life Space in Older AdultsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03483402
Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT05844384
Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority TrialNo drug interventionsotherNot Availablerecruiting
NCT02792803
A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of GlaucomaNo drug interventionstreatment4unknown_status
NCT02247284
Reproducibility of RNFL and ONH Measurements in OAG With Heidelberg Spectralis SD-OCT Glaucoma Module Premium EditionNo drug interventionsdiagnosticNot Availablecompleted
NCT02355990
Minimally Invasive Micro Sclerostomy First in Man Safety and Preliminary Performance StudyNo drug interventionstreatmentNot Availablecompleted
NCT02143843
An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 ProductNo drug interventionstreatment2completed
NCT02042703
Imaging Lens Deposits in Exfoliation SyndromeNo drug interventionsNot AvailableNot Availableterminated
NCT02024464
Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT01943721
A Study of the VISION5 Product in Patients With Glaucoma or Ocular HypertensionNo drug interventionsprevention1completed
NCT01162603
Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP)No drug interventionstreatment4completed
NCT00804102
Transcorneal Electrical Stimulation Therapy for Retinal DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT00300079
Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular HypertensionNo drug interventionstreatment4completed
NCT06177678
A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment2not_yet_recruiting
NCT05786196
Multicenter Glaucoma Study Investigating Standalone CanaloplastyNo drug interventionstreatmentNot Availablerecruiting
NCT05351307
Retinal Vascular Changes in Primary Open Angle Glaucoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05315206
Multimodal Morpho-functional Study in Glaucoma Patients-Citicoline Oral SolutionNo drug interventionstreatmentNot Availablerecruiting
NCT05279716
Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyltreatment4unknown_status
NCT04784234
Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetinNo drug interventionstreatmentNot Availableunknown_status
NCT04742283
Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT04654611
Tafluprost Preservative Free Switch Studytreatment4completed
NCT04609345
Prevalence of Ocular Surface Disease in Malaysian Glaucoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04333433
PRESERFLO® MicroShunt Extension StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03889652
Optical Coherence Tomography of Nerve Fiber Layer and Ganglion Cell Complex After Cataract ExtractionNo drug interventionsNot AvailableNot Availablecompleted
NCT03782051
Combined Viscocanalostomy, Phacoemulsification, OIogen Implant in Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT03651336
Long-term Safety and Performance of the ARGOS-IO Intraocular Pressure Sensor System in Subjects With Primary Open Angle Glaucoma (POAG)No drug interventionsdiagnosticNot Availablecompleted
NCT03480711
Modified Trabeculectomy With an ESST Versus Conventional SST for Management of Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT03127813
PAIR Study-PAP And IOP Relationship: Study 1No drug interventionsbasic_scienceNot Availableterminated
NCT03193333
PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)treatment3recruiting
NCT05439161
XEN Glaucoma Gel Stent Versus TrabeculectomyNo drug interventionstreatmentNot Availablerecruiting
NCT05253534
GlaucoT Glaucoma Treatment Glasses in the Treatment of Primary Open-Angle GlaucomaNo drug interventionstreatmentNot Availablesuspended
NCT05898997
Regulation of Intraocular Pressure in Glaucoma Patients by AcupressureNo drug interventionstreatmentNot Availablecompleted
NCT03419975
A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patientstreatment3completed
NCT03395535
Laser-1st vs Drops-1st for Glaucoma and Ocular HypertensionNo drug interventionstreatment4completed
NCT03331770
Efficacy and Tolerability of an Innovative Formulation of BAK-free Latanoprosttreatment4completed
NCT03098316
Metabolomics in Surgical Ophthalmological PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03065036
Safety and Efficacy Study of the Hydrus Aqueous Implant in Subjects With POAGNo drug interventionstreatment1 / 2completed
NCT05432245
MINIject Implantation Combined With Cataract Surgery in Patients With POAG and CataractNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT02801617
Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertensiontreatment3terminated
NCT02989207
Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-CaribbeanstreatmentNot Availableunknown_status
NCT02617459
Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02537015
An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Inserttreatment2completed
NCT02330978
Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma.No drug interventionstreatment1completed
NCT01979913
An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in Patients With Ocular Hypertension or Primary Open Angle Glaucoma With an Uncontrolled Intraocular Pressure of 30 mmHg and Moretreatment4completed
NCT01930487
The Effects of an Antioxidant Formulation on Ocular Blood FlowNo drug interventionsbasic_scienceNot Availablecompleted
NCT01881425
InnFocus MicroShunt Versus Trabeculectomy StudyNo drug interventionstreatmentNot Availablecompleted
NCT01864317
Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor ImagingNo drug interventionsbasic_science2terminated
NCT01836042
Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket CohortNo drug interventionsNot AvailableNot Availablecompleted
NCT01841437
Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT01818115
Safety and Efficacy Trial to Evaluate the Hydrus(TM) Implant in Subjects Undergoing Cataract Surgery.No drug interventionstreatmentNot Availablecompleted
NCT01798732
PIO Laser Sclerectomy IOP SLT SclerectomyNo drug interventionstreatmentNot Availablecompleted
NCT01563237
Safety and Performance of Miami InnFocus Drainage Implant (MIDI Arrow) Glaucoma Drainage ImplantNo drug interventionstreatmentNot Availablecompleted
NCT01560975
IOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airway PressureNo drug interventionsdiagnosticNot Availablecompleted
NCT01539239
Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)No drug interventionstreatmentNot Availablecompleted
NCT01520116
Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertensiontreatment1 / 2unknown_status
NCT01461278
Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT01410188
Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT01391078
Comparison of Sensimed Triggerfish With Goldmann Applanation Tonometry and Perkins TonometryNo drug interventionsdiagnosticNot Availablecompleted
NCT01364207
The Effects of Caffeinated Coffee on Intraocular PressureNo drug interventionsNot AvailableNot Availablecompleted
NCT01217853
24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation TonometryNo drug interventionsNot AvailableNot Availablecompleted
NCT01062971
Clinical Study of A Fixed Combination of Timolol-Brimonidine-Dorzolamidetreatment2completed
NCT00864578
Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Maximum Tolerated Medical TherapyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00675207
Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogstreatment4completed
NCT00626847
How Does Your Genetic Make-up (Profile) Influence Your Glaucoma?No drug interventionsNot AvailableNot Availablecompleted
NCT00465348
The Antioxidant Effect of Routine Vascular Therapy for Normal Tension Glaucoma PatientsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00347893
The Efficacy of Selective Laser TrabeculoplastyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00327405
Results of Ocular Compression and Suture Release in Trabeculectomy and Combined SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT00280345
Autoimmune Dysregulation in Pigmentary GlaucomaNo drug interventionsbasic_scienceNot Availablecompleted
NCT00330577
24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patientstreatment4completed
NCT02539745
Associations of Vitamin D Deficiency and Vitamin D Receptor Polymorphisms With the Risk of Primary Open-angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT06465537
CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC MutationNo drug interventionstreatmentNot Availablerecruiting
NCT06407973
A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Pseudophakic Eyestreatment4recruiting
NCT05940623
Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma ProgressionNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT05466526
Microinvasive Glaucoma Surgery -The Lowering Effect of Intraocular Pressure on Glaucoma Patients With High Frequency Deep SclerotomyNo drug interventionstreatmentNot Availablerecruiting
NCT04891588
Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSDNo drug interventionstreatmentNot Availableunknown_status
NCT04863365
A Study of Efficacy and Safety of PHP-201 in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment3unknown_status
NCT04830397
Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).No drug interventionstreatment2completed
NCT04769453
Multicenter Ab-interno Glaucoma Study Investigating CanaloplastyNo drug interventionstreatmentNot Availableterminated
NCT04595227
Glaucoma Screening Using Dynamic Analysis of Computerized Pupillary Light Reflex Assessment DeviceNo drug interventionsNot AvailableNot Availableunknown_status
NCT04461249
Comparison Between Latanoprost , Travoprost and Tafluprost in Reducing IOP Fluctuation in POAG PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04448223
A Clinical Study to Evaluate the Efficacy and Safety of CKD-351No drug interventionstreatment2unknown_status
NCT04334564
Effect of Ginkgo Biloba Capsule on Visual Function of Primary Open-angle Glaucoma With Blood Stasis SyndromeNo drug interventionstreatmentNot Availableunknown_status
NCT06321562
Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucomaother1recruiting
NCT06313749
Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite PolypharmacyNo drug interventionstreatmentNot Availablerecruiting
NCT04202510
IOP and Medication Reduction in MIGS ProceduresNo drug interventionstreatmentNot Availablewithdrawn
NCT04155164
Effect of Metformin on Visual Function in Patients With GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT04098861
Efficacy and Safety of Latanoprost/Timolol for Primary Open Angle GlaucomaNo drug interventionstreatment4unknown_status
NCT03931564
SIGHT Study: Cost-effectiveness of InnFocus Microshunt Implantation vs. Trabeculectomy.No drug interventionstreatmentNot Availableactive_not_recruiting
NCT03145129
PAIR Study-PAP And IOP Relationship: Study 2No drug interventionsNot AvailableNot Availablecompleted
NCT04629521
Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-StentNo drug interventionsotherNot Availablecompleted
NCT05557721
Uddevalla Skövde Transscleral Micropulse StudyNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05564091
Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle GlaucomaNo drug interventionstreatmentNot Availablerecruiting
NCT04405245
Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle GlaucomaNo drug interventionstreatment2completed
NCT03365778
Educational Intervention to Adopt SLT as First-Line Glaucoma TreatmentNo drug interventionsotherNot Availablecompleted
NCT03323164
Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography StudyNo drug interventionsdiagnostic4completed
NCT03257813
Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)No drug interventionstreatment3completed
NCT03273907
Post Approval Study of the CyPass SystemNo drug interventionstreatmentNot Availableterminated
NCT03104621
Efficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma PatientsNo drug interventionstreatment4completed
NCT02959593
The Effects of Visior on Ocular HemodynamicsNo drug interventionsotherNot Availablecompleted
NCT03235232
BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular HypertensionNo drug interventionstreatment3completed
NCT02406833
Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing TrabeculectomyNo drug interventionstreatment1completed
NCT02327312
Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser TrabeculoplastyNo drug interventionstreatmentNot Availableterminated
NCT02144103
Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous NeurodegenerationNo drug interventionstreatment1 / 2unknown_status
NCT02059278
Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT02023242
Comparing Effectiveness of the Hydrus Microstent (TM) to Two iStents to Lower IOP in Phakic EyesNo drug interventionstreatmentNot Availablecompleted
NCT02016898
The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration DeviceNo drug interventionstreatment2completed
NCT02006693
Evaluation of the XEN Implant in Moderate Primary Open Angle Glaucoma (POAG) ParticipantsNo drug interventionstreatment4completed
NCT01841450
Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract SurgeryNo drug interventionstreatmentNot Availableunknown_status
NCT01766947
IOP Fluctuations in Primary Open Angle Glaucoma Patients Before and After Deep SclerectomyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01767753
IOP Fluctuations in Patients With Primary Open-angle Glaucoma, Before and After Selective Laser TrabeculoplastyNo drug interventionsNot AvailableNot Availablecompleted
NCT01769521
Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAGNo drug interventionsNot AvailableNot Availablecompleted
NCT01711177
Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT01561001
IOP Fluctuations in Primary Open Angle Glaucoma Patients Before and After Deep Sclerectomy With Collagen ImplantNo drug interventionsdiagnosticNot Availableterminated
NCT01528111
Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1 / 2completed
NCT01494753
Pharmacokinetics, Efficacy and Safety Assessment of T2345 Compared With Active Comparator in Newly Diagnosed Patients With Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT01390779
Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens SensorNo drug interventionsdiagnosticNot Availablecompleted
NCT01409421
RESEARCH PROTOCOL: Glaucoma Treatment Adherence and PersistenceNo drug interventionssupportive_careNot Availablecompleted
NCT01384149
EXTERNAL SLT Treatment in Patients With Uncontrolled OPEN ANGLE GLAUCOMANo drug interventionstreatment1completed
NCT01346904
a 3.0T Magnetic Resonance Imaging StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01301378
Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device TubeNo drug interventionstreatmentNot Availableterminated
NCT01281020
Adherence With Fixed Versus Unfixed Glaucoma TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT01168414
A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT01110499
Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT00863811
Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Treatment With Either Beta-blockers or Prostaglandins Eye DropsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00803504
Correlation of Optic Disk Morphology and Ocular Perfusion Parameters in Patients With Primary Open Angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00773877
Comparison of Retinal Nerve Fiber Layer (RNFL) Thickness Measurements by Time-Domain and Spectral-Domain OCT In Glaucoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00739154
Protective Effect of Phenytoin on GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00676637
Glaucoma Adherence StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00595101
A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.No drug interventionstreatment2completed
NCT00572455
Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.No drug interventionstreatment2completed
NCT00485108
Anti-inflammatory Therapy Following Selective Laser TrabeculoplastyNo drug interventionstreatmentNot Availablecompleted
NCT00476138
Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early GlaucomaNo drug interventionssupportive_care1 / 2unknown_status
NCT00441883
Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for GlaucomaNo drug interventionstreatment2completed
NCT00443664
External Micropulse Diode Laser Transscleral Trabeculoplasty (EMDLT) for Severe Open Angle GlaucomaNo drug interventionstreatment0unknown_status
NCT00221897
Diagnostic Innovations in Glaucoma StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06223048
A Study of AMDX-2011P in Participants With Primary Open Angle GlaucomaNo drug interventionsdiagnostic2recruiting
NCT06144918
Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye PressureNo drug interventionstreatment2completed
NCT06526416
The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patients Who Will Undergo Planned Goniectomy for Uncontrolled POAG, Anterior Segment OCT Scan Will Be Used to Evaluate the Anterior Chamber Postoperatively.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05264818
Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle GlaucomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04828057
Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World SettingNo drug interventionsNot AvailableNot Availablecompleted
NCT04747808
Study of LL-BMT1 in Patients With Elevated Intraocular PressureNo drug interventionstreatment2completed
NCT04519814
Safety and Effectiveness of VISULAS Green Selective Laser Trabeculoplasty (SLT)No drug interventionstreatmentNot Availableunknown_status
NCT04284514
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic SolutionNo drug interventionstreatment1completed
NCT04620135
Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT04141865
Effect of Xen Implantation on the Aqueous Humor ProteomeNo drug interventionsNot AvailableNot Availableterminated
NCT03921931
Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot StudyNo drug interventionsbasic_scienceNot Availablerecruiting
NCT03762369
A Clinical Study to Evaluate the Efficacy and Safety of CKD-351No drug interventionstreatment3unknown_status
NCT03673644
Impact of Glaucoma and Visual Field Loss on Life SpaceNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04553523
Hydrus® Microstent New Enrollment Post-Approval StudyNo drug interventionstreatmentNot Availablerecruiting
NCT05022004
A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT05247762
Effect of Acupuncture on Visual Acuity and Visual Field in Patients With Primary Open-angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT05557058
GORE Glaucoma Drainage Implant Clinical Study Dominican RepublicNo drug interventionstreatmentNot Availablerecruiting
NCT05695027
Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical StudyNo drug interventionssupportive_care2 / 3recruiting
NCT05605743
Alternate Nostril Breathing Training in Geriatrics With Glaucoma and High Blood PressureNo drug interventionstreatmentNot Availablerecruiting
NCT05871034
Electroretinogram and Retinal Vascular Changes After Cataract SurgeryNo drug interventionsotherNot Availablenot_yet_recruiting
NCT05666440
Visco-Circumferential-Suture-Trabeculotomy Versus Rigid Probe Viscotrabeculotomy in Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04440527
Intraocular Pressure After Preserflo / Innfocus Microshunt Implantation vs TrabeculectomyNo drug interventionstreatmentNot Availableunknown_status
NCT04430296
Cyclophotocoagulation in Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT02805257
Ahmed Glaucoma Valve Surgery With Mitomycin-CNo drug interventionstreatment2completed
NCT02863224
Advanced Glycation End Products as a Biomarker for Accelerated AgeingNo drug interventionsNot AvailableNot Availablecompleted
NCT02891317
Assessing Ocular Hemodynamic Response to Surgical Intervention in GlaucomaNo drug interventionsNot AvailableNot Availableterminated
NCT03021629
Comparison of Vitamin D Status and Vitamin D Receptor Polymorphisms in Patients With High Myopia and Primary Open-angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02623738
A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-No drug interventionstreatment2 / 3completed
NCT02544646
Changes in Ocular Rigidity After Trabeculectomy in Patients With POAGNo drug interventionsdiagnosticNot Availablecompleted
NCT02300818
Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion.No drug interventionstreatment1 / 2unknown_status
NCT02358369
Dose-Ranging Study of the Bimatoprost Ocular InsertNo drug interventionstreatment2completed
NCT02177123
Post Market Study of the InnFocus MicroShuntNo drug interventionstreatmentNot Availablecompleted
NCT02077231
Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02047630
Efficacy of the Brand-name Latanoprost and One of Its Generic Version in Primary Open Angle Glaucoma and Ocular HypertensionNo drug interventionstreatment4terminated
NCT02017327
Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit DoseNo drug interventionstreatment4completed
NCT02028572
Structure Function Correlation in Primary Open Angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01915940
Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT01896180
Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by LatanoprostNo drug interventionstreatment2completed
NCT01887223
Transconjunctival Needling Revision Versus Medical TreatmentNo drug interventionstreatment2completed
NCT01795014
Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01742104
Multicentric Observational Study on Quality of Life in GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01742819
Advanced Glaucoma Progression StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01668524
ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) SubjectsNo drug interventionstreatment2completed
NCT01540331
Efficacy And Safety of Pneumatic TrabeculoplastyNo drug interventionstreatment4completed
NCT01461291
Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT01442896
STudy to Assess Rapid Disease Progression by Clinical and Genetic Factors In Glaucoma patientS That Are High RiskNo drug interventionsNot AvailableNot Availablecompleted
NCT01379144
A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular HypertensionNo drug interventionstreatment2completed
NCT00947869
Contrast Sensitivity in GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00773123
Efficacy of Retinal Nerve Fiber Layer (RNFL) / Ganglion Cell Layer Thickness Ratio by RT-View Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma.No drug interventionsNot AvailableNot Availableunknown_status
NCT00680329
Glaucoma Adherence Study, SpainNo drug interventionsNot AvailableNot Availablecompleted
NCT00494923
Early Diagnosis, Pathogenesis and Progression of Open Angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00372827
Study of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment4completed
NCT00331240
24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed CombinationNo drug interventionstreatment3completed
NCT00346931
Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular PressureNo drug interventionstreatmentNot Availableterminated
NCT00284440
Choroidal Blood Flow Response to Hand-grip Test in Progressive GlaucomaNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00221923
African Descent and Glaucoma Evaluation StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03924544
Decorin in Sub Scleral TrabeculectomyNo drug interventionstreatment1unknown_status
NCT02805231
Associations of Vitamin D Receptor ApaI and Tru9I Polymorphisms With the Risk of Primary Open-angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01917383
A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucomatreatment2completed
NCT02829996
Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAGtreatment2completed
NCT02565173
Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucomatreatment3completed
NCT06437639
MEXIDOL® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)No drug interventionstreatment4completed
NCT02226094
Safety and Efficacy of Deep Wave Trabeculoplasty (DWT) in Primary Open Angle Glaucoma and Ocular HypertensionNo drug interventionstreatment1 / 2terminated
NCT03131167
Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle GlaucomaNo drug interventionstreatment1completed
NCT05539508
Role of Peripheral Vision in Scene Perception (PERISCE)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00230763
Determination Of Predictive Factors Allowing To An Additional 10% Reduction Of Intra-Ocular Pressuretreatment3completed
NCT01737853
Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT02858284
Evaluation of Safety and Efficacy of TUG (Therapeutic Ultrasound for Glaucoma) in the Treatment of Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatmentNot Availableterminated
NCT05370287
Adaptive Optics Retinal ImagingNo drug interventionsbasic_scienceNot Availablerecruiting
NCT01853085
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical ReasonsNot AvailableNot Availablecompleted
NCT03067415
Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Dailytreatment2unknown_status
NCT01833741
A Study of LUMIGAN® RC in the Clinical Settingtreatment4completed
NCT04899063
Excimer Laser Trabeculostomy Glaucoma Treatment StudyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01999348
A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical SettingNot AvailableNot Availablecompleted
NCT02796560
Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT03800589
Assessment of Effectiveness Ex-Press Surgery ModificationNo drug interventionstreatmentNot Availablecompleted
NCT05181046
Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma PatientsNo drug interventionstreatmentNot Availablecompleted
NCT03675412
Caffeine Consumption in Glaucoma Patients and Healthy SubjectsNo drug interventionsdiagnosticNot Availablerecruiting
NCT04465864
Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone InsertNo drug interventionstreatment4completed
NCT05673954
Glaucoma Assessment Via Reading AbilityNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03151577
Longitudinal Study on Glaucoma Surgery Using XEN® Gel StentNo drug interventionstreatmentNot Availableunknown_status
NCT01814761
A Study of Bimatoprost 0.01% in the Clinical SettingNo drug interventionsNot AvailableNot Availablecompleted
NCT04737928
Prospective, Single Center Switching Study of 0.0015% Tafluprost Ophthalmic Solution in Primary Open-angle Glaucoma and Ocular Hypertension Patients With Corneal Disorders (Switching From 0.005% Latanoprost Ophthalmic Solution)No drug interventionstreatmentNot Availablecompleted
NCT06053307
Treating Psychosocial Distress in GlaucomaNo drug interventionsotherNot Availablenot_yet_recruiting
NCT04149899
Safety and IOP-Lowering Effects of WB007No drug interventionstreatment1 / 2completed
NCT05999006
Safety and Feasibility of the ELIOS System in POAG PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT05964634
Effect of Peripapillary Atrophy to Diagnose Glaucoma in High MyopiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05474716
The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of POAG Using OCTANo drug interventionstreatment4completed
NCT04321122
UCP (Ultrasound Cyclo Plasty) in the Treatment of Chinese Patients With Primary Open-angle GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT02679482
Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04007276
The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma PatientsNo drug interventionstreatment4not_yet_recruiting
NCT01408472
NT-501 CNTF Implant for Glaucoma: Safety, Neuroprotection and NeuroenhancementNo drug interventionstreatment1completed
NCT03318510
LSFG in Patients With Normal Tension Glaucoma Tension GlaucomaNo drug interventionsdiagnosticNot Availableunknown_status
NCT02700984
A Study to Assess Long-Term Safety of the CyPass Micro-Stent in Patients Completing the COMPASS TrialNo drug interventionsotherNot Availablecompleted
NCT01517477
One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma SubjectsNo drug interventionstreatmentNot Availablecompleted
NCT03478293
iStent Inject in OAG Subjects on 2 Pre-op Topical Ocular Hypotensive MedicationsNo drug interventionstreatmentNot Availableterminated
NCT00902109
Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01166659
Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical TherapyNo drug interventionstreatmentNot Availablecompleted
NCT01252849
Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma SubjectsNo drug interventionstreatmentNot Availablecompleted
NCT01085357
Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT01180062
Safety Study of Latanoprost Slow Release InsertNo drug interventionstreatment1terminated
NCT02434692
Safety and Performance Study of the ARGOS-IO (Intraocular) System in Patients With Primary Open Angle Glaucoma (POAG)No drug interventionsdiagnosticNot Availablecompleted
NCT06016972
Qlaris Phase 2 Study of QLS-111 in POAG and/or OHT PatientsNo drug interventionstreatment2active_not_recruiting
NCT04727411
Analysis of Conjunctival Changes as Indicators for Ab-interno Gelatin Microstent Implantation Surgery OutcomesNo drug interventionsbasic_scienceNot Availablecompleted
NCT03310788
Monitoring of the IOP After SLT Using iCare HomeNo drug interventionsNot AvailableNot Availableunknown_status
NCT05455567
OCTA Study of Choroidal Vasculature in Open Angle Glaucoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT06572397
Open-Label Study of Safety of H1337 in Healthy VolunteersNo drug interventionstreatment1not_yet_recruiting
NCT03875911
Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in TrabeculectomyNo drug interventionstreatment4terminated
NCT05913232
Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment2active_not_recruiting
NCT04295122
Comparing the Effectiveness of Phacoemulsification + ECP Laser and Phacoemulsification Alone for Glaucoma PatientsNo drug interventionstreatment4unknown_status
NCT05495061
A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed