Colorectal Cancer (CRC) Completed Phase 1 Trials for Oxaliplatin (DB00526)

Back to Colorectal Cancer (CRC)

Also known as: Malignant Neoplasm of Colorectum / CRC, Colorectal Cancer / Colorectal Cancer / Cancer, Colorectal / CRC (Colorectal Cancer) / Colorectal, Cancer / Colo-rectal Cancer / Colorectal Cancers / A. Colorectal Cancer / Cancer Colorectal / Gastrointestinal Cancers - Colorectal / CRC / CRCS / Malignant colorectal neoplasm / Malignant neoplasm of cecum and/or colon and/or rectum / Malignant neoplasm of caecum and/or colon and/or rectum / Malignant neoplasm of cecum and/or colon and/or rectum (disorder) / Malignant neoplasm of large intestine / Malignant tumor of large intestine / Malignant tumour of large intestine / Malignant neoplasm of large intestine (disorder) / Malignant neoplasm of colon, unspecified / Malignant large intestinal neoplasm NOS / Cancer of large intestine / Malignant neoplasm of large intestine, NOS / Cancer of large bowel / CA - Cancer of large bowel / Colorectal neoplasms malignant / Malignant neoplasm of colon and/or rectum (disorder) / Large intestine carcinoma / Colorectal carcinoma / Colorectal cancer NOS

Indication	Status	Phase
DBCOND0031867 (Colorectal Cancer (CRC))	Completed	1

clinicaltrials.gov Identifier	Title	Purpose	Drugs
NCT04761614	Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Leucovorin (DB00650) Levoleucovorin (DB11596) Oxaliplatin (DB00526) Riluzole (DB00740)
NCT04164069	Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab	Prevention	Bevacizumab (DB00112) Dasatinib (DB01254) Fluorouracil (DB00544) Leucovorin (DB00650) Levoleucovorin (DB11596) Oxaliplatin (DB00526)
NCT00166465	Stage IV Colorectal CA ALIMTA	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526) Pemetrexed (DB00642)
NCT03798626	Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers	Treatment	Bevacizumab (DB00112) Cabozantinib (DB08875) Fluorouracil (DB00544) Gevokizumab (DB12119) Irinotecan (DB00762) Leucovorin (DB00650) Oxaliplatin (DB00526) Paclitaxel (DB01229) Ramucirumab (DB05578)
NCT03720678	A Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal Malignancies	Treatment	Etrumadenant (DB17506) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT03597581	A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Ompenaclid (DB18819) Oxaliplatin (DB00526)
NCT03428958	A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment	Treatment	Bevacizumab (DB00112) Cetuximab (DB00002) Fosifloxuridine nafalbenamide (DB14859) Irinotecan (DB00762) Leucovorin (DB00650) Oxaliplatin (DB00526) Panitumumab (DB01269)
NCT00873275	Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526) Ursodeoxycholic acid (DB01586)
NCT00059930	Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer	Treatment	Dexamethasone (DB01234) Floxuridine (DB00322) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00004187	Capecitabine and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer	Treatment	Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT02833753	Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI	Treatment	Oxaliplatin (DB00526)
NCT00199797	Phase I Trial of huA33 Plus Chemotherapy in Patients With Metastatic Colorectal Cancer	Treatment	Fluorouracil (DB00544) Hua33 (DB33781) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00345761	Clinical Study of Capecitabine, Oxaliplatin and Bevacizumab in Colorectal Cancer	Treatment	Bevacizumab (DB00112) Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT00118261	Erlotinib, Modified FOLFOX6, and Bevacizumab as First-Line Therapy Metastatic Colorectal Cancer	Treatment	Bevacizumab (DB00112) Erlotinib (DB00530) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT01047293	RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma	Treatment	Bevacizumab (DB00112) Everolimus (DB01590) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT02062749	Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma	Treatment	Oxaliplatin (DB00526)
NCT01110941	Feasibility Study of SOL (S-1,Oral Leucovorin,and Oxaliplatin) for Colorectal Cancer in China	Treatment	Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT01420874	Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00098982	Bortezomib, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer	Treatment	Bortezomib (DB00188) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00086931	Oxaliplatin, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Rectum	Treatment	Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT00019773	Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer	Treatment	Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT00008294	Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer	Treatment	Dexamethasone (DB01234) Floxuridine (DB00322) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT05116891	A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors	Treatment	Cisplatin (DB00515) Docetaxel (DB01248) Fluorouracil (DB00544) Gemcitabine (DB00441) Leucovorin (DB00650) Nadunolimab (DB18249) Oxaliplatin (DB00526)
NCT00353262	A Study of Xeloda (Capecitabine) in Combination With Oxaliplatin in Patients With Metastatic Colorectal Cancer.	Treatment	Bevacizumab (DB00112) Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT00049101	Erlotinib and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer	Treatment	Erlotinib (DB00530) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00501410	FOLFOX Chemotherapy Regimen (5-FU, Leucovorin, Oxaliplatin) in Metastatic Colorectal Cancer	Treatment	Cetuximab (DB00002) Dasatinib (DB01254) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00343408	AZD2171 and Standard Combination Chemotherapy in Advanced Non-Small Cell Lung Cancer or Colorectal Cancer	Treatment	Cediranib (DB04849) Cisplatin (DB00515) Fluorouracil (DB00544) Gemcitabine (DB00441) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT03253133	Assessing Safety of NIPOX in Peritoneal Carcinomatosis of CRC	Treatment	Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Oxaliplatin (DB00526) Oxycodone (DB00497)
NCT00217711	Oxaliplatin, Irinotecan, and Capecitabine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Cannot Be Removed By Surgery	Treatment	Capecitabine (DB01101) Irinotecan (DB00762) Oxaliplatin (DB00526)
NCT00458809	Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer	Treatment	Oxaliplatin (DB00526)
NCT01164215	Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00081237	OSI-7904L and Oxaliplatin in Treating Patients With Refractory or Recurrent Advanced Colorectal Cancer	Treatment	OSI-7904L (DB05457) Oxaliplatin (DB00526)
NCT00026299	Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer	Treatment	Gefitinib (DB00317) Oxaliplatin (DB00526)
NCT01193517	Azacitidine and CAPOX in Metastatic Colorectal Cancer	Treatment	Azacitidine (DB00928) Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT03314935	A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors	Treatment	Cisplatin (DB00515) Fluorouracil (DB00544) Gemcitabine (DB00441) Leucovorin (DB00650) Numidargistat (DB15286) Oxaliplatin (DB00526) Paclitaxel (DB01229)
NCT02574663	TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Gemcitabine (DB00441) Leucovorin (DB00650) Oxaliplatin (DB00526) Paclitaxel (DB01229) Umbralisib (DB14989)
NCT00055822	Combination Chemotherapy and Oblimersen in Treating Patients With Advanced Colorectal Cancer	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT01803282	Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Chemotherapy in Participants With Advanced Solid Tumors	Treatment	Andecaliximab (DB12296) Bevacizumab (DB00112) Carboplatin (DB00958) Gemcitabine (DB00441) Irinotecan (DB00762) Leucovorin (DB00650) Oxaliplatin (DB00526) Paclitaxel (DB01229) Pemetrexed (DB00642)
NCT00003427	Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer	Treatment	Irinotecan (DB00762) Oxaliplatin (DB00526)
NCT03564912	Prospective Study on the Efficacy and Safety of 2 Week or 3 Week Xelox Regimen for Adjuvant Chemotherapy in CRC	Treatment	Capecitabine (DB01101) Oxaliplatin (DB00526)
NCT00005050	Eniluracil, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Colorectal Cancer	Treatment	Fluorouracil (DB00544) Oxaliplatin (DB00526)
NCT00532909	Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal Cancer	Treatment	Bevacizumab (DB00112) Capecitabine (DB01101) Oxaliplatin (DB00526) Vandetanib (DB05294)