Colorectal Cancer (CRC) Terminated Phase 2 Trials for Fluorouracil (DB00544)

Back to Colorectal Cancer (CRC)

Also known as: Malignant Neoplasm of Colorectum / CRC, Colorectal Cancer / Colorectal Cancer / Cancer, Colorectal / CRC (Colorectal Cancer) / Colorectal, Cancer / Colo-rectal Cancer / Colorectal Cancers / A. Colorectal Cancer / Cancer Colorectal / Gastrointestinal Cancers - Colorectal / CRC / CRCS / Malignant colorectal neoplasm / Malignant neoplasm of cecum and/or colon and/or rectum / Malignant neoplasm of caecum and/or colon and/or rectum / Malignant neoplasm of cecum and/or colon and/or rectum (disorder) / Malignant neoplasm of large intestine / Malignant tumor of large intestine / Malignant tumour of large intestine / Malignant neoplasm of large intestine (disorder) / Malignant neoplasm of colon, unspecified / Malignant large intestinal neoplasm NOS / Cancer of large intestine / Malignant neoplasm of large intestine, NOS / Cancer of large bowel / CA - Cancer of large bowel / Colorectal neoplasms malignant / Malignant neoplasm of colon and/or rectum (disorder) / Large intestine carcinoma / Colorectal carcinoma / Colorectal cancer NOS

Indication	Status	Phase
DBCOND0031867 (Colorectal Cancer (CRC))	Terminated	2

clinicaltrials.gov Identifier	Title	Purpose	Drugs
NCT02508077	FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer	Treatment	Camptothecin (DB04690) Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Levoleucovorin (DB11596) Panitumumab (DB01269)
NCT01715363	Feasibility of an Immediate Preoperative Chemotherapy Before Resection fo Colorectal Cancer	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT05983367	A Study to Investigate Ompenaclid Combined With FOLFIRI Plus Bevacizumab in Advanced/Metastatic Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Ompenaclid (DB18819)
NCT05678257	A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Fosifloxuridine nafalbenamide (DB14859) Irinotecan (DB00762) Leucovorin (DB00650)
NCT05039944	SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System Malignancies	Treatment	Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Oxaliplatin (DB00526) SI-B001 (DB21939)
NCT00766142	Chemotherapy and Cetuximab in Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer	Treatment	Cetuximab (DB00002) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00006015	Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526) Trastuzumab (DB00072)
NCT00755118	Lohp, 5-Fu/Lv and Bevacizumab, Alternative With Cpt-11, 5-Fu/Lv and Cetuximab In Metastatic Crc	Treatment	Bevacizumab (DB00112) Cetuximab (DB00002) Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT01479465	Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma	Treatment	Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650) Simtuzumab (DB12152)
NCT00602329	MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer	Diagnostic	Bevacizumab (DB00112) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00537823	Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement	Treatment	Bevacizumab (DB00112) Cetuximab (DB00002) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00601198	A Study of Amifostine (Ethyol) in Patients With Colorectal Cancer	Treatment	Amifostine (DB01143) Bevacizumab (DB00112) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00323011	FOLFIRI + Bevacizumab With or Without Dalteparin in First Line Treatment of Advanced Colorectal Cancer	Treatment	Bevacizumab (DB00112) Dalteparin (DB06779) Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650)
NCT00006037	Chemotherapy Plus IM-862 in Treating Patients With Metastatic Colorectal Cancer	Treatment	Fluorouracil (DB00544) Irinotecan (DB00762) Oglufanide (DB05779)
NCT01375816	Liposome-encapsulated Irinotecan Hydrochloride PEP02 or Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil as Second-Line Therapy in Treating Patients With Metastatic Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Irinotecan (DB00762) Leucovorin (DB00650)
NCT00005944	Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer	Treatment	Fluorouracil (DB00544) Leucovorin (DB00650) Mitomycin (DB00305)
NCT00043004	Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00541112	Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery	Treatment	Capecitabine (DB01101) Cetuximab (DB00002) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT02141295	A Study Comparing the Efficacy and Safety of Vanucizumab and FOLFOX With Bevacizumab and FOLFOX in Participants With Untreated Metastatic Colorectal Cancer	Treatment	Bevacizumab (DB00112) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526) Vanucizumab (DB12317)
NCT03050814	Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004	Treatment	Ad-CEA vaccine (DB17581) Avelumab (DB11945) Bevacizumab (DB00112) Capecitabine (DB01101) Fluorouracil (DB00544) Leucovorin (DB00650) Oxaliplatin (DB00526)
NCT00209703	Feasibility Study of mFOLFOX6 in Patients With Advanced Colorectal Cancer	Treatment	Fluorouracil (DB00544) Levoleucovorin (DB11596) Oxaliplatin (DB00526)
NCT00110721	GM-CT-01 Plus 5-Fluorouracil as Third- or Fourth-Line Therapy for Metastatic Colorectal Cancer	Treatment	Davanat (DB15311) Fluorouracil (DB00544)