Sulfotransferase 4A1
Details
- Name
- Sulfotransferase 4A1
- Synonyms
- 2.8.2.-
- Brain sulfotransferase-like protein
- hBR-STL
- hBR-STL-1
- Nervous system sulfotransferase
- NST
- ST4A1
- SULTX3
- Gene Name
- SULT4A1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052142|Sulfotransferase 4A1 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL
- Number of residues
- 284
- Molecular Weight
- 33084.615
- Theoretical pI
- Not Available
- GO Classification
- Functionsidentical protein binding / sulfotransferase activityProcesses3'-phosphoadenosine 5'-phosphosulfate metabolic process / steroid metabolic processComponentscytosol
- General Function
- Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.
- Specific Function
- Identical protein binding
- Pfam Domain Function
- Sulfotransfer_1 (PF00685)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0052143|Sulfotransferase 4A1 (SULT4A1) ATGGCGGAGAGCGAGGCCGAGACCCCCAGCACCCCGGGGGAGTTCGAGAGCAAGTACTTC GAGTTCCATGGCGTGCGGCTGCCGCCCTTCTGCCGCGGGAAGATGGAGGAGATCGCCAAC TTCCCGGTGCGGCCCAGCGACGTGTGGATCGTCACCTACCCCAAGTCCGGCACCAGCTTG CTGCAGGAGGTGGTCTACTTGGTGAGCCAGGGCGCTGACCCCGATGAGATCGGCTTGATG AACATCGACGAGCAGCTCCCGGTCCTGGAGTACCCACAGCCGGGCCTGGACATCATCAAG GAACTGACCTCTCCCCGCCTCATCAAGAGCCACCTGCCCTACCGCTTTCTGCCCTCTGAC CTCCACAATGGAGACTCCAAGGTCATCTATATGGCTCGCAACCCCAAGGATCTGGTGGTG TCTTATTATCAGTTCCACCGCTCTCTGCGGACCATGAGCTACCGAGGCACCTTTCAAGAA TTCTGCCGGAGGTTTATGAATGATAAGCTGGGCTACGGCTCCTGGTTTGAGCACGTGCAG GAGTTCTGGGAGCACCGCATGGACTCGAACGTGCTTTTTCTCAAGTATGAAGACATGCAT CGGGACCTGGTGACGATGGTGGAGCAGCTGGCCAGATTCCTGGGGGTGTCCTGTGACAAG GCCCAGCTGGAAGCCCTGACGGAGCACTGCCACCAGCTGGTGGACCAGTGCTGCAACGCT GAGGCCCTGCCCGTGGGCCGGGGAAGAGTTGGGCTGTGGAAGGACATCTTCACCGTCTCC ATGAATGAGAAGTTTGACTTGGTGTATAAACAGAAGATGGGAAAGTGTGACCTCACGTTT GACTTTTATTTATAA
- Chromosome Location
- 22
- Locus
- 22q13.31
- External Identifiers
Resource Link UniProtKB ID Q9BR01 UniProtKB Entry Name ST4A1_HUMAN HGNC ID HGNC:14903 - General References
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Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details DB00871 Terbutaline approved unknown substrate Details DB00960 Pindolol approved, investigational unknown substrate Details DB00968 Methyldopa approved no substrate Details DB12471 Ibrexafungerp approved, investigational unknown substrate Details DB00867 Ritodrine approved, investigational no substrate Details DB12243 Edaravone approved, investigational no substrate Details