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Displaying results 91 - 100 of 226 in total
  1. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA) [A32837 … , and aminolevulinic acid.

    Mixtures: Folic Acid Plus, B6, B12 & Folic Acid
  2. Pathway

    Eszopiclone Action Pathway

    smpdb.ca/view/SMP0126150
    Drug action

    Eszopiclone is a sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic dr...

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Eszopiclone · Calcium · Magnesium cation +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  3. Pathway

    Glutethimide Action Pathway

    smpdb.ca/view/SMP0126131
    Drug action

    Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs. It can be found under the brand name Doriden and is used to treat insomnia. The hypnotic effect is roughly analogous to that of pentobarbital. I...

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Morphine · Codeine · Calcium +6 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  4. Pathway

    Brexanolone Action Pathway

    smpdb.ca/view/SMP0126148
    Drug action

    Brexanolone can be found under the brand name Zulresso, and it is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females. Since PPD, like various other types...

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Progesterone · Calcium · Magnesium cation +4 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  5. Pathway

    Primidone Action Pathway

    smpdb.ca/view/SMP0126166
    Drug action

    Primidone is an antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. Primidone alters sodium and calcium channel transport, reducing the frequency of nerve firing, which may be responsible for its effect on c...

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Primidone · Phenobarbital · Calcium +5 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  6. Pathway

    Topiramate Action Pathway (New)

    smpdb.ca/view/SMP0125139
    Drug action

    Topiramate is a weak inhibitor of carbonic anhydrase; acidosis in the brain has partial protection against seizures by downregulating NMDA receptor activity.

    Drugs: L-Glutamine · Topiramate · Calcium · gamma-Aminobutyric acid
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid receptor subunit alpha-1
  7. Pathway

    Pentazocine Opioid Antagonist Action Pathway

    smpdb.ca/view/SMP0126325
    Drug action

    Pentazocine also prevents the gamma subunit of the mu opioid receptor from inhibiting the N-type calcium channels on the neuron. This allows calcium to enter the neuron and depolarize.

    Drugs: ATP · Pentazocine · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +1 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  8. Pathway

    Diprenorphine Action Pathway

    smpdb.ca/view/SMP0126341
    Drug action

    Diprenorphine also prevents the gamma subunit of the mu opioid receptor from inhibiting the N-type calcium channels on the neuron. This allows calcium to enter the neuron and depolarize.

    Drugs: ATP · Calcium · Magnesium cation · Diprenorphine · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +1 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  9. Pathway

    Dezocine Kappa Opioid Antagonism Action Pathway

    smpdb.ca/view/SMP0125013
    Drug action

    Dezocine also prevents the gamma subunit of the kappa opioid receptor from inhibiting the N-type calcium channels on the neuron. This allows calcium to enter the neuron and depolarize.

    Drugs: ATP · Dezocine · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +1 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  10. Pathway

    Normethadone Action Pathway

    smpdb.ca/view/SMP0126829
    Drug action

    Normethadone is an opioid antitussive used to treat a cough associated with inflamed mucosa. Normethadone binds to mu opioid receptors, stimulating the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate...

    Drugs: ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid · Pyrophosphoric acid +1 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2