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Protein S100-A16
go.drugbank.com/bio_entities/BE0008707TargetHumansCalcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity).
Synonyms: S100 calcium-binding protein A16Function: calcium ion bindingProtein S100-A12
go.drugbank.com/bio_entities/BE0001206TargetHumansS100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.
Synonyms: S100 calcium-binding protein A12, Calcium-binding protein in amniotic fluid 1Function: calcium ion bindingEukaryotic elongation factor 2 kinase
go.drugbank.com/bio_entities/BE0011325TargetHumansThreonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, ...
Synonyms: Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinaseProtein S100-A1
go.drugbank.com/bio_entities/BE0001090TargetHumansIn response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes (PubMed:23351007). … Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600).
Synonyms: S100 calcium-binding protein A1Ryanodine receptor 2
go.drugbank.com/bio_entities/BE0005295TargetTransporterHumansIn cardiac myocytes, calcium release is triggered by increased Ca(2+) cytosolic levels due to activation of the L-type calcium channel CACNA1C. … The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development
Synonyms: Cardiac muscle ryanodine receptor-calcium release channelFunction: calcium channel activityRyanodine receptor 3
go.drugbank.com/bio_entities/BE0005296TransporterTargetHumansContributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling … May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells.
Synonyms: Brain ryanodine receptor-calcium release channelFunction: calcium ion bindingProtein S100-A11
go.drugbank.com/bio_entities/BE0002789TargetHumansFacilitates the differentiation and the cornification of keratinocytes
Synonyms: S100 calcium-binding protein A11Protein S100-A6
go.drugbank.com/bio_entities/BE0002950TargetHumansBinds 2 calcium ions. Calcium binding is cooperative … May function as calcium sensor and modulator, contributing to cellular calcium signaling.
Synonyms: S100 calcium-binding protein A6Function: calcium ion bindingTransient receptor potential cation channel subfamily M member 4
go.drugbank.com/bio_entities/BE0009748TargetHumansCalcium-activated selective cation channel that mediates membrane depolarization (PubMed:12015988, PubMed:12842017, PubMed:29211723, PubMed:30528822). … Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization.
Synonyms: Calcium-activated non-selective cation channel 1Cystine/glutamate transporter
go.drugbank.com/bio_entities/BE0000030TargetTransporterHumansHeterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane (PubMed:11133847, PubMed:11417227, PubMed:14722095, P...
Synonyms: Calcium channel blocker resistance protein CCBR1