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Displaying results 91 - 100 of 470 in total
  1. Target

    Excitatory amino acid transporter 1

    go.drugbank.com/bio_entities/BE0001115
    TargetTransporterHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515, … Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940).

    Polypeptides: Excitatory amino acid transporter 1
  2. Target

    Fatty acid-binding protein, heart

    go.drugbank.com/bio_entities/BE0001201
    CarrierHumans

    FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters

    Polypeptides: Fatty acid-binding protein, heartSynonyms: Fatty acid-binding protein 3, Muscle fatty acid-binding protein
  3. Target

    Fatty-acid amide hydrolase 1

    go.drugbank.com/bio_entities/BE0002194
    TargetEnzymeHumans

    FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets … of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity)

    Polypeptides: Fatty-acid amide hydrolase 1Synonyms: Fatty acid ester hydrolase
  4. Target

    Excitatory amino acid transporter 5

    go.drugbank.com/bio_entities/BE0002267
    TargetHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. … Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:9108121).

    Polypeptides: Excitatory amino acid transporter 5
  5. Target

    Vesicular inhibitory amino acid transporter

    go.drugbank.com/bio_entities/BE0002308
    TransporterHumans

    The transport is equally dependent on the chemical and electrical components of the proton gradient (By similarity). May also transport beta-alanine (By similarity).

    Polypeptides: Vesicular inhibitory amino acid transporterSynonyms: GABA and glycine transporter
  6. Target

    Cyclopropane mycolic acid synthase 3

    go.drugbank.com/bio_entities/BE0002521
    TargetMycobacterium tuberculosis

    It can use cis, cis 11,14-eicosadienoic acid and linoelaidic acid as substrate. … Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence.

    Polypeptides: Cyclopropane mycolic acid synthase 3Synonyms: Cyclopropane fatty acid synthase, Mycolic acid methyltransferase
  7. Target

    Fatty acid metabolism regulator protein

    go.drugbank.com/bio_entities/BE0003045
    TargetBacillus subtilis (strain 168)

    Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. … Transcriptional regulator in fatty acid degradation.

    Polypeptides: Fatty acid metabolism regulator protein
  8. Target

    Fatty acid-binding protein TM_1468

    go.drugbank.com/bio_entities/BE0003182
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Binds long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

    Polypeptides: Fatty acid-binding protein TM_1468
  9. Target

    Hepatic sodium/bile acid cotransporter

    go.drugbank.com/bio_entities/BE0003644
    TransporterTargetHumans

    It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate (PubMed:14660639, PubMed:34060352 … Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic

    Polypeptides: Hepatic sodium/bile acid cotransporterSynonyms: Na(+)/bile acid cotransporter
  10. Target

    Fatty acid metabolism regulator protein

    go.drugbank.com/bio_entities/BE0004232
    TargetEscherichia coli (strain K12)

    Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE (PubMed:9388199). … Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the

    Polypeptides: Fatty acid metabolism regulator protein