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Displaying results 91 - 100 of 818 in total
  1. Indication

    Hypotonic Dehydration

    go.drugbank.com/conditions/DBCOND0135077
    Drugs: Potassium chloride · Sodium chloride
  2. Pathway

    Quinethazone Action Pathway

    smpdb.ca/view/SMP0123030
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood.

    Drugs: Quinethazone · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  3. Pathway

    Indapamide Diuretic Action Pathway

    smpdb.ca/view/SMP0123031
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood.

    Drugs: Indapamide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  4. Pathway

    Torasemide Action Pathway (New)

    smpdb.ca/view/SMP0124537
    Drug action

    Torasemide binds to NKCC2 transporter and inhibits it, preventing Na+, K+ and Cl- reabsorption from the lumen. … The K+/Cl- co-transporter moves K+ and Cl- from the cell into the peritubular fluid and the Cl- channel transports Cl- from the cell into the peritubular fluid.

    Drugs: Torasemide · Potassium cation
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  5. Pathway

    Hydrochlorothiazide Action Pathway

    smpdb.ca/view/SMP0000100
    Drug action

    Solute carrier family 12 member 3 transports chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of sodium to basolateral interstitium to provide sodium … It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent water reabsorption.

    Drugs: Cysteine · Hydrochlorothiazide · Potassium cation · Urea
    Enzymes: Sodium- and chloride-dependent transporter XTRP3, Chloride channel protein ClC-Ka
  6. Pathway

    Hydrochlorothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0122688
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … pumps Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood.

    Drugs: Hydrochlorothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  7. Drug

    Magnesium gluconate

    go.drugbank.com/drugs/DB13749
    ApprovedWithdrawn

    Although magnesium is available in the form of sulphates, lactate, hydroxide, oxide and chloride, only magnesium gluconate is recommended for magnesium supplementation as it appears to be better absorbed … and laxatives) [L2601].

    Mixtures: NUTROPLEX LIQUID WITH IRON AND LYSINECategories: Alimentary Tract and Metabolism
  8. Pathway

    Chlorthalidone Action Pathway

    smpdb.ca/view/SMP0000122
    Drug action

    Solute carrier family 12 member 3 transports chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of sodium to basolateral interstitium to provide sodium … It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent water reabsorption.

    Drugs: Cysteine · Chlorthalidone · Potassium cation · Urea
    Enzymes: Sodium- and chloride-dependent transporter XTRP3, Chloride channel protein ClC-Ka
  9. Pathway

    Bumetanide Diruretic Action Pathway

    smpdb.ca/view/SMP0124517
    Drug action

    Bumetanide binds to NKCC2 transporter and inhibits it, preventing Na+, K+ and Cl- reabsorption from the lumen. … The K+/Cl- co-transporter moves K+ and Cl- from the cell into the peritubular fluid and the Cl- channel transports Cl- from the cell into the peritubular fluid.

    Drugs: Bumetanide · Potassium cation
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  10. Pathway

    Chlorothiazide Action Pathway

    smpdb.ca/view/SMP0123141
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occurs. … Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood.

    Drugs: Chlorothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1