Search

Displaying results 1001 - 1010 of 10000 in total
  1. Target

    Coagulation factor XIII A chain

    go.drugbank.com/bio_entities/BE0000004
    TargetEnzymeHumans

    Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot

    Polypeptides: Coagulation factor XIII A chainSynonyms: Transglutaminase A chain, Protein-glutamine gamma-glutamyltransferase A chain
  2. Target

    L-lactate dehydrogenase A chain

    go.drugbank.com/bio_entities/BE0000425
    TargetHumans

    Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)

    Polypeptides: L-lactate dehydrogenase A chainSynonyms: LDH-A
  3. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000429
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  4. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000798
    TargetEscherichia coli (strain K12)

    MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation (PubMed:20921377).

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  5. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0001628
    TargetShigella flexneri

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase A
  6. Target

    Glyceraldehyde-3-phosphate dehydrogenase A

    go.drugbank.com/bio_entities/BE0002057
    TargetEscherichia coli (strain K12)

    The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction … The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

    Polypeptides: Glyceraldehyde-3-phosphate dehydrogenase ASynonyms: GAPDH-A
  7. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0002766
    TargetStreptomyces lividans

    Contributes to hydrolyze hemicellulose, the major component of plant cell-walls. XLNA and XLNB seem to act sequentially on the substrate to yield xylobiose and xylose as carbon sources.

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: Xylanase A, 1,4-beta-D-xylan xylanohydrolase A
  8. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0003268
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase A
  9. Target

    Ephrin type-A receptor 7

    go.drugbank.com/bio_entities/BE0004140
    TargetHumans

    Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. … May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity.

    Polypeptides: Ephrin type-A receptor 7
  10. Target

    Acyl-coenzyme A thioesterase 13

    go.drugbank.com/bio_entities/BE0004376
    TargetHumans

    May play a role in controlling adaptive thermogenesis (By similarity) … Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545).

    Polypeptides: Acyl-coenzyme A thioesterase 13