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Necitumumab
go.drugbank.com/drugs/DB09559ApprovedInvestigationalWithdrawnNecitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC). … Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist.
Trimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigationalTrimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. … [A7688,L33020] However, evidence for this mechanism is controversial.[A233215] Trimetazidine is not FDA approved. However, it has been approved in France since 1978.[L33020]
Dexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalin the epithelium[A32373]. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism
Synonyms: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamideMixtures: Daily all in one ample, Daily all in one ampleEprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Synonyms: (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acidCategories: Angiotensin II receptor antagonists, Angiotensin II Type 1 Receptor BlockersFutibatinib
go.drugbank.com/drugs/DB15149ApprovedInvestigationalFGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies … Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and
Synonyms: 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneMethionine
go.drugbank.com/drugs/DB00134ApprovedInvestigationalNutraceuticalA sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Mixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseNasal Polyps
go.drugbank.com/conditions/DBCOND0004147Drugs: BudesonideSynonyms: Polyp in anterior naresChronic Phase Chronic Myeloid Leukemia
go.drugbank.com/conditions/DBCOND0057382Synonyms: CML in Chronic Phase, Chronic Myeloid Leukemia in Chronic PhaseDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]
Products: Vibramycin InjAxatilimab
go.drugbank.com/drugs/DB16388ApprovedInvestigational[A264309] Axatilimab was approved by the FDA in August 2024 for the third-line treatment of cGVHD. … Axatilimab is a humanized IgG4 monoclonal antibody produced in Chinese hamster ovary cells.