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Serine/threonine-protein kinase Nek9
go.drugbank.com/bio_entities/BE0009500TargetHumansPleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817).
Synonyms: Never in mitosis A-related kinase 9Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedIt is sold under several brand names, most notably Tinactin and Odor Eaters. … Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.
Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamideProducts: Opti-Nail 2-in-1, Ongo - FinGlofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigational) after two or more lines of systemic therapy. … , after two or more lines of systemic therapy under accelerated approval based on response rate and durability of response.
Serine/threonine-protein kinase Nek2
go.drugbank.com/bio_entities/BE0003796TargetHumansProtein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. … Involved in the regulation of centrosome disjunction (PubMed:26220856).
Synonyms: Never in mitosis A-related kinase 2Splicing factor 1
go.drugbank.com/bio_entities/BE0009118TargetHumansNecessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor
Synonyms: Zinc finger gene in MEN1 locusTriethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigational[A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and … Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine].
Categories: Compounds used in a research, industrial, or household settingTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries. … It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form.
International brands: Ni Wei FuProducts: Modulon Inj 50mg/5mlClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedIt is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). … This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094].
Mixtures: BAYCUTEN N, BAYCUTEN-NProducts: CLOTRIMAZOLO IG FARMACEUTICI, Terrasil Tinea Treatment MAXPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalIt is used as an ointment base, topical protectant, and lubricant.
Mixtures: CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant, I-defenseCategories: Compounds used in a research, industrial, or household setting