Search

Displaying results 1001 - 1010 of 10000 in total
  1. Target

    Poly(A) polymerase gamma

    go.drugbank.com/bio_entities/BE0018981
    TargetHumans

    Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA

    Polypeptides: Poly(A) polymerase gammaSynonyms: Neo-poly(A) polymerase
  2. Drug

    Propofol

    go.drugbank.com/drugs/DB00818
    ApprovedInvestigationalVet approved

    IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. … Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia.

    Synonyms: 2,6-bis(1-methylethyl)phenolInternational brands: IV-Pro
  3. Drug

    Succinylcholine

    go.drugbank.com/drugs/DB00202
    ApprovedInvestigational

    [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.

    Synonyms: 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)Products: Suxamethonium Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze, Anectine Inj 20mg/ml
  4. Target

    Lipid A palmitoyltransferase PagP

    go.drugbank.com/bio_entities/BE0001965
    TargetEscherichia coli (strain K12)

    Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

    Polypeptides: Lipid A palmitoyltransferase PagPSynonyms: Lipid A acylation protein
  5. Target

    Dihydroorotate dehydrogenase A (fumarate)

    go.drugbank.com/bio_entities/BE0002008
    TargetLactococcus lactis subsp. cremoris

    Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.

    Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD A
  6. Target

    Group A nerve fibers

    go.drugbank.com/bio_entities/BE0009708
    TargetRat

  7. Target

    BCL11 transcription factor A

    go.drugbank.com/bio_entities/BE0019545
    TargetHumans

    Involved in brain development (PubMed:27453576). May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity). … Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene (PubMed:29606353, PubMed:39423807).

    Polypeptides: BCL11 transcription factor A
  8. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. It is a major metabolic intermediate in most organisms. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].

    Mixtures: Hands First 4 in 1, Mycellcare All in One SerumCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Dimercaprol

    go.drugbank.com/drugs/DB06782
    Approved

    In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. … Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: α,β-dithioglycerol, 1,2-dimercapto-3-propanol
  10. Drug

    Evolocumab

    go.drugbank.com/drugs/DB09303
    ApprovedInvestigational

    It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line therapies. … Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen.

    Products: REPATHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 140MG/ML, Repatha Solution for Injection in Pre-filled Syringe 140mg/mL (evolocumab)