Search

Displaying results 1031 - 1040 of 10000 in total
  1. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    [A253762] It was also approved by the European Commission on January 7, 2021.[L43712] … Tagraxofusp is a CD123-directed cytotoxin.

    Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor
  2. Pathway

    Ergoloid mesylate Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0126658
    Drug action

    Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...

    Drugs: Pyridoxal phosphate · Tyrosine · ATP · Dopamine · Ergoloid mesylate · Levodopa +5 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  3. Pathway

    Thiethylperazine Dopamine Antagonist Action Pathway

    smpdb.ca/view/SMP0126476
    Drug action

    Thiethylperazine' s antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors.

    Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Thiethylperazine · Dopamine · Levodopa +2 more
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  4. Pathway

    Megestrol acetate Action Pathway

    smpdb.ca/view/SMP0126528
    Drug action

    Megestrol acetate is a synthetic progestational hormone initially developed as a contraceptive. Nowadays, it is used as a drug to treat anorexia and cachexia (or unexplained weight loss) and as an antineoplastic agent to treat inoperable...

    Drugs: NADH · ATP · Megestrol acetate · Progesterone · Testosterone · Estrone +9 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  5. Pathway

    Norelgestromin Action Pathway

    smpdb.ca/view/SMP0126539
    Drug action

    Norelgestromin is a synthetic progestational hormone indicated in women to prevent pregnancy. This drug is also used in menopausal hormonal therapy. This drug is administered as a contraceptive pill or as a transdermal patch. This drug i...

    Drugs: NADH · ATP · Progesterone · Testosterone · Estrone · Potassium cation +9 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  6. Drug

    Prucalopride

    go.drugbank.com/drugs/DB06480
    ApprovedInvestigational

    [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018.[L4880] … Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: RESOLOR ® TABLETAS RECUBIERTAS DE 2 MG, RESOLOR ® TABLETAS RECUBIERTAS DE 1 MG
  7. Drug

    Teriparatide

    go.drugbank.com/drugs/DB06285
    ApprovedInvestigational

    [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent.[A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH.

    Synonyms: PTH 1-34, PTH (1-34)Products: TEOTIDE®, TERROSA®
  8. Pathway

    Ziprasidone Dopamine Antagonist Action Pathway

    smpdb.ca/view/SMP0126472
    Drug action

    Ziprasidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and acute agitation in schizophrenic patients. It also indicated improvement on the manic syndrome subscale that measures symptoms of mania such as mood...

    Drugs: Pyridoxal phosphate · Tyrosine · Ziprasidone · Sapropterin · Dopamine · Levodopa +2 more
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  9. Pathway

    Etonogestrel Action Pathway

    smpdb.ca/view/SMP0126525
    Drug action

    Etonogestrel is a synthetic metabolite of progestin desosgestrel. This drug is a long-acting progestin contraceptive used mostly in intradermal implants that are releasing 40 mcg/day of the drug for 3 years. Etonogestrel binds strongly t...

    Drugs: NADH · ATP · Etonogestrel · Progesterone · Testosterone · Estrone +9 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  10. Pathway

    Progesterone Action Pathway

    smpdb.ca/view/SMP0126529
    Drug action

    Progesterone is a hormone naturally occurring in females. This molecule is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. It is used as an oral drug as a contraceptive to preven...

    Drugs: NADH · ATP · Progesterone · Testosterone · Estrone · Potassium cation +8 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12