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Chloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigationalSimilar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. … Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride.
Synonyms: 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate, 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl esterProducts: Ampres 10 mg/ml Injektionslösung, Ampres 20 mg/ml InjektionslösungNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalIt appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Categories: Heterocyclic Compounds with 4 or More RingsSynonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriolAcylcarnitine (5Z)-7-{2-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoylcarnitine
smpdb.ca/view/SMP0123542Metabolic(5Z)-7-{2-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoylcarnitine is an acylcarnitine. … membrane to once again form (5Z)-7-{2-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoyl-CoA and L-carnitine. (5Z)-7-{2-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigational[L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. … The FDA approved ketamine (Ketalar) in 1970.
Synonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanoneCategories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists, Cytochrome P-450 SubstratesAluminum zirconium tetrachlorohydrex gly
go.drugbank.com/drugs/DB11149ApprovedWithdrawnAluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent.
Mixtures: Ban Ultra Antiperspirant Roll-ONProducts: Mitchum M3 Invisible Solid, Arrid Xx Extra Extra Dry Roll-ON Lot 20%Canakinumab
go.drugbank.com/drugs/DB06168ApprovedInvestigationalIt is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. … Both heavy chains of canakinumab contain oligosaccharide chains linked to the protein backbone at asparagine 298 (Asn 298).
Products: IBECTA 150 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 4 ADET, ILARIS® SOLUCIÓN INYECTABLE 150 MG/ MLAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalAt this time, more than 35 clinical trials across 40 countries with more than 2500 patients are underway or have been completed with regards to further research into better understanding and expanding … received at least one prior therapy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: CALQUENCE 100 MG SERT KAPSÜL, 56 ADET, CALQUENCE 100 MG SERT KAPSÜL, 60 ADETMaraviroc
go.drugbank.com/drugs/DB04835ApprovedInvestigationalIt was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: CELSENTRI® 150 MG, CELSENTRI 150 MG FILM KAPLI TABLET ,180 ADETEssential Thrombocythemia (ET)
go.drugbank.com/conditions/DBCOND0048758Synonyms: ET (Essential Thrombocythemia), Essential Thrombocythemia (ET)Moclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalMost meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamide