Search

Displaying results 1041 - 1050 of 10000 in total
  1. Drug

    SIG-205

    go.drugbank.com/drugs/DB18548
    Experimental

    SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer

  2. Drug

    Levmetamfetamine

    go.drugbank.com/drugs/DB09571
    Approved

    Levomethamphetamine, the L-enantiomer of methamphetamine is a sympathomimetic vasoconstrictor used in some over-the-counter (OTC) nasal decongestant inhalers in the United States.

    Products: Sinu Inhaler
  3. Drug

    Chondroitin sulfate

    go.drugbank.com/drugs/DB09301
    ApprovedInvestigationalNutraceutical

    [A32063] Chondroitin sulfate is sold as an OTC dietary supplement in North America and it is a prescription drug under the EMA in Europe.[A32066] … Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA).

    Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: Sun Chondroitin., Kordel"s Chondroitin 400mg
  4. Drug

    Nitrous oxide

    go.drugbank.com/drugs/DB06690
    ApprovedInvestigationalVet approved

    At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. … Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O.

    Mixtures: Nitrous Oxide In Oxygen, OXICALM®Products: N/A
  5. Drug

    SIM-6802

    go.drugbank.com/drugs/DB33648
    Investigational

    Categories: Heterocyclic Compounds, 2-Ring
  6. Target

    3-hydroxy-3-methylglutaryl-coenzyme A reductase

    go.drugbank.com/bio_entities/BE0000574
    TargetEnzymeHumans

    HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668, PubMed:36745799) … Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular

    Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseFunction: coenzyme A binding
  7. Target

    Acetyl-coenzyme A synthetase 2-like, mitochondrial

    go.drugbank.com/bio_entities/BE0000746
    TargetHumans

    Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity) … Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity).

    Polypeptides: Acetyl-coenzyme A synthetase 2-like, mitochondrial
  8. Target

    2-amino-3-ketobutyrate coenzyme A ligase

    go.drugbank.com/bio_entities/BE0002049
    TargetEscherichia coli (strain K12)

    Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.

    Polypeptides: 2-amino-3-ketobutyrate coenzyme A ligase
  9. Target

    2,5-diketo-D-gluconic acid reductase A

    go.drugbank.com/bio_entities/BE0002618
    TargetCorynebacterium sp. (strain ATCC 31090)

    Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity

    Polypeptides: 2,5-diketo-D-gluconic acid reductase ASynonyms: 2,5-DKG reductase A
  10. Target

    A-type voltage-gated potassium channel KCND2

    go.drugbank.com/bio_entities/BE0003603
    TargetHumans

    In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes. … Functions downstream of the metabotropic glutamate receptor GRM5 and plays a role in neuronal excitability and in nociception mediated by activation of GRM5 (By similarity).

    Polypeptides: A-type voltage-gated potassium channel KCND2Function: A-type (transient outward) potassium channel activity