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Sodium channel protein type 1 subunit alpha
go.drugbank.com/bio_entities/BE0000141TargetHumansPore-forming subunit of Nav1.1, a voltage-gated sodium (Nav) channel that directly mediates the depolarizing phase of action potentials in excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dep...
Synonyms: Sodium channel protein brain I subunit alpha, Sodium channel protein type I subunit alphaIoflupane I-123 Predicted Metabolism Pathway
smpdb.ca/view/SMP0174587MetabolicMetabolites of Ioflupane I-123 are predicted with biotransformer.
N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)
go.drugbank.com/drugs/DB11202ApprovedIt is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. … N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties.
Salts: N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14)Mixtures: Mevon No. 72 Liq, Med-I-SanTolfenamic acid
go.drugbank.com/drugs/DB09216Approved[L1292] In the US, it presents a Status class I by the FDA. By the European Medicine Agency, it was granted in 2016 with the status of orphan for the treatment of supranuclear palsy.[L1291] … [A31824] It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam.
Categories: Non COX-2 selective NSAIDS, Analgesics, Non-NarcoticProducts: TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS, Tolfine Solution for Injection 4.0% W/VProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
go.drugbank.com/bio_entities/BE0002373TargetHumansEssential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth posit...
Synonyms: GGTase-I-alpha, Type I protein geranyl-geranyltransferase subunit alphaIron
go.drugbank.com/drugs/DB01592ApprovedInvestigationalIron is used to build up the blood in anemia. … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems.
International brands: Ed-In-Sol, Fer-In-SolMixtures: Spectrum 2 Cap, Spark CapDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and
Mixtures: DORZOLOL® UD, Van-dorzolamide-timololCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingTGF-beta receptor type-1
go.drugbank.com/bio_entities/BE0003782TargetHumansTransmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signa...
Synonyms: TbetaR-I, TGF-beta receptor type IRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigationalelevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. … [A181523] This last point results in less risk of drug-drug interactions compared to [atorvastatin], [lovastatin], and [simvastatin], which are all extensively metabolized by Cytochrome P450 (CYP) 3A4,
Mixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20Categories: Drugs Used in Diabetes, Cytochrome P-450 Substrates