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Desomorphine Opioid Agonist Action Pathway
smpdb.ca/view/SMP0126807Drug actionDesomorphine binds to opioid receptors on the presynaptic membrane, stimulating the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membran...
Drugs: ATP · Calcium · Magnesium cation · Desomorphine · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +2 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Levacetylmethadol Opioid Agonist Action Pathway
smpdb.ca/view/SMP0126826Drug actionLevacetylmethadol, also known as Levomethadyl acetate, Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It was withdrawn from the European Union due to its high risk of QT interval prolongation. Its pro...
Drugs: ATP · Levacetylmethadol · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +2 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Hydromorphone Opioid Agonist Action Pathway
smpdb.ca/view/SMP0125017Drug actionHydromorphone is an opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. It is a pure opioid,1 a semi-synthetic hydrogenated ketone derivative of morphine. Hydromorphone is indicated for the mana...
Drugs: ATP · Hydromorphone · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +2 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Anileridineb Opioid Agonist Action Pathway
smpdb.ca/view/SMP0126794Drug actionAnileridineb is a synthetic opioid analgesic medication. It is a narcotic pain reliever used to treat severe pain. It can be taken intramuscularly, intravenously, subcutaneously, or orally. Anileridineb binds to mu opioid receptors, stim...
Drugs: ATP · Anileridine · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +2 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Benzhydrocodone Opioid Agonist Action Pathway
smpdb.ca/view/SMP0126825Drug actionBenzhydrocodone is a benzylic prodrug of hydrocodone.It was developed to reduce parenteral bioavailability of the active metabolite as a deterrent of abuse.It was first approved by the FDA in February 2018 in combination with acetaminoph...
Drugs: ATP · Hydrocodone · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +4 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Diamorphine Action Pathway
smpdb.ca/view/SMP0125174Drug actionDiamorphine (heroin) is a narcotic analgesic used to manage pain and to induce feelings of eurphoria. It is illegal in most countries, but in the UK it is legal so long as prescribed under the name diamorphine instead of heroin. It is a ...
Drugs: ATP · Morphine · Calcium · Magnesium cation · Diamorphine · Cyclic adenosine monophosphate +3 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Trimethadione Action Pathway
smpdb.ca/view/SMP0126340Drug actionTrimethadione is an anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. Parameth...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Trimethadione · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 1Methsuximide Action Pathway
smpdb.ca/view/SMP0126331Drug actionMethsuximide is a succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in abse...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +3 moreEnzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 1Ethosuximide Action Pathway
smpdb.ca/view/SMP0126318Drug actionEthosuximide is an anticonvulsant used to treat petit mal seizures. It can be found under the brand name Zarontin. An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures. Used in...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Ethosuximide · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 1Paramethadione Action Pathway
smpdb.ca/view/SMP0126675Drug actionParamethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome. It is used for the control of absence (petit mal) seizures that are re...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Paramethadione · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 1