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Displaying results 101 - 110 of 2763 in total
  1. Target

    c-Jun N-terminal kinases

    go.drugbank.com/bio_entities/BE0009865
    TargetHumans

    Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. … Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway.

    Polypeptides: Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 8Synonyms: Stress-activated protein kinase 1b, Stress-activated protein kinase 1c
  2. Target

    Antitumor antibiotic C-1027 apoprotein

    go.drugbank.com/bio_entities/BE0001994
    TargetStreptomyces globisporus

    Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.

    Polypeptides: Antitumor antibiotic C-1027 apoproteinSynonyms: C-1027-AG
  3. Target

    High-molecular-weight cytochrome c

    go.drugbank.com/bio_entities/BE0001749
    TargetDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)

    HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic

    Polypeptides: High-molecular-weight cytochrome c
  4. Target

    C-1-tetrahydrofolate synthase, cytoplasmic

    go.drugbank.com/bio_entities/BE0000617
    TargetHumans

    Trifunctional enzyme that catalyzes the interconversion of three forms of one-carbon-substituted tetrahydrofolate: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate, 5,10-methenyltetrahydrofolate and (6S)-10-formyltetrahydrofolate (PubMed:108...

    Polypeptides: C-1-tetrahydrofolate synthase, cytoplasmicSynonyms: Epididymis secretory sperm binding protein
  5. Target

    C-Jun-amino-terminal kinase-interacting protein 1

    go.drugbank.com/bio_entities/BE0003789
    TargetHumans

    The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. … Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response.

    Polypeptides: C-Jun-amino-terminal kinase-interacting protein 1Synonyms: Mitogen-activated protein kinase 8-interacting protein 1, JNK-interacting protein 1
  6. Target

    Cytochrome c nitrite reductase subunit NrfH

    go.drugbank.com/bio_entities/BE0004129
    TargetDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)

    Electron donor subunit of the cytochrome c nitrite reductase holocomplex NrfHA.

    Polypeptides: Cytochrome c nitrite reductase subunit NrfHSynonyms: Cytochrome c-type protein, Cytochrome c-type protein NrfH
  7. Target

    Complement C1q subcomponent subunit C

    go.drugbank.com/bio_entities/BE0002096
    TargetHumans

    Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens

    Polypeptides: Complement C1q subcomponent subunit C
  8. Target

    Ubiquitin C-terminal hydrolase 7

    go.drugbank.com/bio_entities/BE0018040
    TargetHumans

    Involved in the regulation of WASH-dependent actin polymerization at the surface of endosomes and the regulation of endosomal protein recycling (PubMed:26365382). … Plays a role in the maintenance of the circadian clock periodicity via deubiquitination and stabilization of the CRY1 and CRY2 proteins (PubMed:27123980).

    Polypeptides: Ubiquitin C-terminal hydrolase 7
  9. Target

    Cytochrome c nitrite reductase subunit NrfA

    go.drugbank.com/bio_entities/BE0004130
    TargetDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)

    Catalytic subunit of the cytochrome c nitrite reductase holocomplex NrfHA (PubMed:11004582, PubMed:17139260, PubMed:18597779, PubMed:25534748).

    Polypeptides: Cytochrome c nitrite reductase subunit NrfASynonyms: Cytochrome c-type protein NrfA, Cytochrome c-552
  10. Target

    Peptidyl-prolyl cis-trans isomerase C

    go.drugbank.com/bio_entities/BE0002333
    TargetHumans

    PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding

    Polypeptides: Peptidyl-prolyl cis-trans isomerase CSynonyms: PPIase C, Rotamase C