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Membrane-associated progesterone receptor component 1
go.drugbank.com/bio_entities/BE0004896TargetHumansForms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization (PubMed:30443021)
Polypeptides: Membrane-associated progesterone receptor component 1GABA(A) Receptor Benzodiazepine Binding Site
go.drugbank.com/bio_entities/BE0008668TargetHumansGABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response (By similarity). … GABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response in a gamma-2 subunit-controlled manner (By similarity)
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Taste receptor type 2 member 16
go.drugbank.com/bio_entities/BE0009016TargetHumansGustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
Polypeptides: Taste receptor type 2 member 16Function: bitter taste receptor activityBone morphogenetic protein receptor type-1A
go.drugbank.com/bio_entities/BE0009272TargetHumansOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. … Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Polypeptides: Bone morphogenetic protein receptor type-1ASynonyms: BMP type-1A receptor, Activin receptor-like kinase 3Bone morphogenetic protein receptor type-2
go.drugbank.com/bio_entities/BE0009324TargetHumansOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
Polypeptides: Bone morphogenetic protein receptor type-2Synonyms: BMP type II receptor, BMP type-2 receptorBone morphogenetic protein receptor type-1B
go.drugbank.com/bio_entities/BE0009415TargetHumansReceptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction … On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
Polypeptides: Bone morphogenetic protein receptor type-1BSynonyms: BMP type-1B receptorInterleukin-1 receptor-associated kinase 1
go.drugbank.com/bio_entities/BE0009452TargetHumansInvolved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation.
Polypeptides: Interleukin-1 receptor-associated kinase 1Receptor tyrosine-protein kinase erbB-3
go.drugbank.com/bio_entities/BE0009917TargetHumansTyrosine kinase receptor that, despite substitutions of key catalytic residues in the kinase domain, retains residual catalytic activity enabling autophosphorylation (PubMed:9148746, PubMed:20351256).
Polypeptides: Receptor tyrosine-protein kinase erbB-3Synonyms: Tyrosine kinase-type cell surface receptor HER3Advanced glycation end product-specific receptor
go.drugbank.com/bio_entities/BE0010032TransporterTargetHumansCell surface pattern recognition receptor that senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein
Polypeptides: Advanced glycation end product-specific receptorSynonyms: Receptor for advanced glycation end products, Advanced glycosylation end product-specific receptorHepatitis A virus cellular receptor 2
go.drugbank.com/bio_entities/BE0010551TargetHumansReceptor for LGALS9 (PubMed:16286920, PubMed:24337741). … However, the function as receptor for LGALS9 has been challenged (PubMed:23555261).
Polypeptides: Hepatitis A virus cellular receptor 2Synonyms: T-cell immunoglobulin mucin receptor 3