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Zoliflodacin

[A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking … [A274938,L54748] It is indicated as a single-dose oral therapy for the treatment of uncomplicated urogenital gonorrhea.

Pectin

Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants.[A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. … [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or as acid amides.

Succimer

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

Dyphylline

Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.

Trolamine salicylate

It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. … It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin irritant properties [A32191].

Varenicline

The FDA said it is keeping the black box in place at least until the results of the trial are announced. … Pfizer is conducting an additional safety study of the drug, results of which are expected in late 2015.

Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)

Mequinol

Mequinol is a phenol used in various applications. … It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines.

Ajmaline

It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. … The drug has been very popular in some countries for the treatment of atrial fibrillation in patients with the Wolff–Parkinson–White syndrome and in well tolerated monomorphic ventricular tachycardias.

Glyburide

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. … [L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin].