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Tumor necrosis factor receptor superfamily member 10A
go.drugbank.com/bio_entities/BE0010564TargetHumansReceptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518, PubMed:38532423). The adapter molecule FADD recruits caspase-8 to the activated receptor.
Polypeptides: Tumor necrosis factor receptor superfamily member 10ASynonyms: Death receptor 4, TRAIL receptor 1Inactive tyrosine-protein kinase transmembrane receptor ROR1
go.drugbank.com/bio_entities/BE0010828TargetHumansReceptor for ligand WNT5A which activates downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350).
Polypeptides: Inactive tyrosine-protein kinase transmembrane receptor ROR1Synonyms: Neurotrophic tyrosine kinase, receptor-related 1Macrophage scavenger receptor types I and II
go.drugbank.com/bio_entities/BE0010942TargetHumansMembrane receptor that mediates the binding, endocytosis and phagocytosis of a broad range of ligands.
Polypeptides: Macrophage scavenger receptor types I and IISynonyms: Scavenger receptor class A member 1, Macrophage acetylated LDL receptor I and IITriggering receptor expressed on myeloid cells 2
go.drugbank.com/bio_entities/BE0020451TargetHumansIn dendritic cells, receptor of SEMA6D with PLEXNA1 as coreceptor and mediates up-regulation of chemokine receptor CCR7 and dendritic cell maturation and survival (PubMed:11602640). … Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849).
Polypeptides: Triggering receptor expressed on myeloid cells 2Synonyms: Triggering receptor expressed on monocytes 2T cell receptor beta variable 5-6
go.drugbank.com/bio_entities/BE0023691TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).
Polypeptides: T cell receptor beta variable 5-6Diatrizoate
go.drugbank.com/drugs/DB00271ApprovedVet approvedA commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Mixtures: MD- GASTROVIEW® (MEDIO DE CONTRASTE PARA RADIOGRAFIA), MD- GASTROVIEW® (MEDIO DE CONTRASTE PARA RADIOGRAFIA)Liotrix
go.drugbank.com/drugs/DB01583ApprovedIt is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. … It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight.
Categories: Agents used to treat hypothyroidismSynonyms: Liotrix (T4;T3)Taprenepag
go.drugbank.com/drugs/DB12623InvestigationalTaprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Categories: Receptors, Prostaglandin E, EP2 Subtype, agonistsCalcium threonate
go.drugbank.com/drugs/DB11168ApprovedWithdrawnTherapeutic efficacy of calcium threonate in reducing was studied and investigated due to the hypothesis that it may play a role in the mineralization process through its positive action on vitamin C. … The most common form is calcium L-threonate, or (2R,3S)-2,3,4-trihydroxy butyric acid calcium [A27266].
Mixtures: Se-Vate 21/7, Se-Care ConceiveSimenepag isopropyl
go.drugbank.com/drugs/DB12977InvestigationalSimenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.