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Octreotide
go.drugbank.com/drugs/DB00104ApprovedInvestigational[L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. … Acromegaly is a life-threatening disease requiring life-long management.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze, Siroctid 0,5 mg/ml Injektionslösung in einer FertigspritzeMethylmalonic aciduria type A protein, mitochondrial
go.drugbank.com/bio_entities/BE0000320TargetHumansAdditionally acts a reactivase by promoting the replacement of OH2Cbl by the active cofactor AdoCbl, restoring the activity of MMUT in the presence and hydrolysis of GTP (PubMed:21138732, PubMed:28943303 … Plays a dual role as both a protectase and a reactivase for MMUT (PubMed:21138732, PubMed:28943303).
Polypeptides: Methylmalonic aciduria type A protein, mitochondrialRibosomal small subunit pseudouridine synthase A
go.drugbank.com/bio_entities/BE0002034TargetEscherichia coli (strain K12)Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase APeroxisomal acyl-coenzyme A oxidase 1
go.drugbank.com/bio_entities/BE0004135TargetEnzymeHumansMay play a role in peroxisomal beta-oxidation step in polyunsaturated fatty acids (PUFAs) biosynthesis. … Involved in VLCFA-dependent hepatic-to-adipose tissue inter-organ signaling in response to diet.
Polypeptides: Peroxisomal acyl-coenzyme A oxidase 1GABA(A) Receptor Benzodiazepine Binding Site
go.drugbank.com/bio_entities/BE0008668TargetHumansExtrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity).
Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activityMHC class I HLA-A protein
go.drugbank.com/bio_entities/BE0010186TargetHumansPolypeptides: MHC class I HLA-A proteinSynonyms: HLA-AHepatitis A virus cellular receptor 2
go.drugbank.com/bio_entities/BE0010551TargetHumansExpressed on natural killer (NK) cells and acts as a coreceptor to enhance IFN-gamma production in response to LGALS9 (PubMed:22323453). … In contrast, shown to activate TCR-induced signaling in T-cells probably implicating ZAP70, LCP2, LCK and FYN (By similarity).
Polypeptides: Hepatitis A virus cellular receptor 2Acyl-coenzyme A thioesterase 2, mitochondrial
go.drugbank.com/bio_entities/BE0013225EnzymeHumansThe enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity) … Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:10944470, PubMed:16940157).
Polypeptides: Acyl-coenzyme A thioesterase 2, mitochondrialSynonyms: Acyl-coenzyme A thioester hydrolase 2aHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. … It is used in industrial and cosmetic applications as a bleaching agent.
Mixtures: Prevention Wound and Burn, BANEN Rinse-free Hand Sanitizer (II)Categories: Compounds used in a research, industrial, or household settingWitch hazel
go.drugbank.com/drugs/DB11111ApprovedInvestigationalNutraceuticalMixtures: Hemorrhoidal Soothing Well at Walgreens, Preparation HProducts: Placenta EX Deep Line, Tone and Line Change Pack