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Displaying results 1161 - 1170 of 10000 in total
  1. Target

    Coenzyme A biosynthesis bifunctional protein CoaBC

    go.drugbank.com/bio_entities/BE0002020
    TargetEscherichia coli (strain K12)

    Catalyzes two sequential steps in the biosynthesis of coenzyme A. … In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine (PubMed:10922366, PubMed:11358972).

    Polypeptides: Coenzyme A biosynthesis bifunctional protein CoaBC
  2. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  3. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0004194
    TargetEscherichia coli (strain K12)

    It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2190212).

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  4. Target

    Platelet-derived growth factor subunit A

    go.drugbank.com/bio_entities/BE0010246
    TargetHumans

    Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. … Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin.

    Polypeptides: Platelet-derived growth factor subunit ASynonyms: PDGF subunit A, Platelet-derived growth factor A chain
  5. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol
  6. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant.

    Mixtures: Alcohol in Dextrose, Nox-A-StingCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates
  7. Indication

    Chronic Myeloid Leukemia in Myeloid Blast Crisis

    go.drugbank.com/conditions/DBCOND0059451
    Drugs: Vindesine
    Synonyms: Blast crisis (qualifier value), Blast crisis in myelogenous leukaemia
  8. Indication

    Refractory Anemia With Excess Blasts in Transformation

    go.drugbank.com/conditions/DBCOND0028567
    Drugs: Azacitidine
    Synonyms: Refractory Anemia With Excess of Blasts in Transformation, Refractory Anemia With Excess Blasts in Transformation
  9. Indication

    Infection in minor cuts, scrapes, or burns

    go.drugbank.com/conditions/DBCOND0021991
    Drugs: Bacitracin · Eucalyptus oil · Iodine
    Synonyms: Infection in minor cuts, scrapes, or burns
  10. Drug

    Human C1-esterase inhibitor

    go.drugbank.com/drugs/DB06404
    ApprovedInvestigational

    [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction … The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several soft tissues or edema, which may last up to five days when untreated.[L16586, L16606]

    Categories: Drugs Used in Hereditary AngioedemaSynonyms: C1-INH