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Displaying results 1171 - 1180 of 10000 in total
  1. Drug

    Zomepirac

    go.drugbank.com/drugs/DB04828
    ApprovedWithdrawn

    The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.

    Categories: Non COX-2 selective NSAIDS, Analgesics, Non-NarcoticSynonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid
  2. Target

    Cytochrome c oxidase subunit 1

    go.drugbank.com/bio_entities/BE0004055
    TargetRhodobacter sphaeroides

    Co I is the catalytic subunit of the enzyme.

    Synonyms: Cytochrome c oxidase polypeptide I
  3. Target

    Calnexin

    go.drugbank.com/bio_entities/BE0001011
    TargetHumans

    Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It...

    Synonyms: Major histocompatibility complex class I antigen-binding protein p88
  4. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

    go.drugbank.com/bio_entities/BE0000081
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-42kD
  5. Target

    Tryptase alpha/beta-1

    go.drugbank.com/bio_entities/BE0003736
    TargetHumans

    Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315)

    Synonyms: Tryptase I
  6. Target

    Nuclear cap-binding protein subunit 2

    go.drugbank.com/bio_entities/BE0013483
    TargetHumans

    In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding … The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound

    Polypeptides: Nuclear cap-binding protein subunit 2Synonyms: 20 kDa nuclear cap-binding protein
  7. Target

    Nuclear cap-binding protein subunit 1

    go.drugbank.com/bio_entities/BE0014101
    TargetHumans

    cap-binding state with the cap structure. … The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound

    Polypeptides: Nuclear cap-binding protein subunit 1Synonyms: 80 kDa nuclear cap-binding protein
  8. Drug

    Thenalidine

    go.drugbank.com/drugs/DB04826
    ApprovedWithdrawn

    Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine, 1-Methyl-4-N-2-thenylanilinopiperidine
  9. Pathway

    Iodohippurate sodium I-131 Drug Metabolism

    smpdb.ca/view/SMP0130590
    Metabolic

    Iodohippurate sodium I-131 passes through the liver and is then excreted from the body mainly through the kidney. … Iodohippurate sodium I-131 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Iodohippurate sodium I-131
  10. Pathway

    Iodohippurate sodium I-123 Drug Metabolism

    smpdb.ca/view/SMP0130602
    Metabolic

    Iodohippurate sodium I-123 passes through the liver and is then excreted from the body mainly through the kidney. … Iodohippurate sodium I-123 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Iodohippurate sodium I-123