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Gastric Acid Production
smpdb.ca/view/SMP0000589PhysiologicalMoreover, the chloride and potassium ions are transported into the stomach lumen through their own channels so that hydrogen ions and/or potassium ions can form an ionic bond with chloride ions to form … The hydrogen ions are available inside the parietal cell after water and carbon dioxide combine to form carbonic acid(the reaction is catalyzed by the carbonic anhydrase enzyme) which dissociates into
Gadoxetic acid Metabolism
smpdb.ca/view/SMP0126873MetabolicGadoxetic acid is a gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver. … The water protons in the vicinity are disrupted such that the change the proton density and spin characteristics are detected and visualized by a device.
Drugs: Gadoxetic acidTranexamic Acid Action Pathway
smpdb.ca/view/SMP0000287Drug actionTranexamic acid is a synthetic version of an amino acid found in the body called lysine that plays a role in antifibrinolytic processes. It is used to stop bleeding and hemorrhaging in patients. … Tranexamic acid inhibits plasminogen.
Lysophosphatidic Acid LPA1 Signalling
smpdb.ca/view/SMP0063746SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 1Lysophosphatidic Acid LPA3 Signalling
smpdb.ca/view/SMP0063755SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 3Gamma-Aminobutyric Acid Biosynthesis
smpdb.ca/view/SMP0125090MetabolicGlutamate is catalyzed in the neuron with the enzyme Glutamate decarboxylase-1 to synthesize GABA and a byproduct of carbon dioxide. … GABA is transported into a synaptic vesicle by Vesicular inhibitory amino acid transporter. The vesicle is activated by calcium entering the presynapse as well as cAMP.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Tolfenamic acid Action Pathway
smpdb.ca/view/SMP0126549Drug actionThe inhibition of both COX-1 and COX-2 by tolfenamic acid reduces the formation of prostaglandin H2 and therefore, prostaglandin E2 (PGE2). … COX-2 is an inducible enzyme, and during inflammation, it is responsible for prostaglandin synthesis.
Acetohydroxamic acid Drug Metabolism
smpdb.ca/view/SMP0130492MetabolicAcetohydroxamic acid passes through the liver and is then excreted from the body mainly through the kidney. … Acetohydroxamic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Acetohydroxamic acidAcetic acid Drug Metabolism
smpdb.ca/view/SMP0130504MetabolicAcetic acid passes through the liver and is then excreted from the body mainly through the kidney. … Acetic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Acetic acidEtidronic acid Drug Metabolism
smpdb.ca/view/SMP0130677MetabolicEtidronic acid passes through the liver and is then excreted from the body mainly through the kidney. … Etidronic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Etidronic acid