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Displaying results 111 - 120 of 4358 in total
  1. Target

    Potassium voltage-gated channel subfamily KQT member 2

    go.drugbank.com/bio_entities/BE0000897
    TargetTransporterHumans

    Pore-forming subunit of the voltage-gated potassium (Kv) M-channel which is responsible for the M-current, a key controller of neuronal excitability (PubMed:24277843, PubMed:28793216, PubMed:9836639).

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 2Synonyms: Voltage-gated potassium channel subunit Kv7.2
  2. Target

    Potassium voltage-gated channel subfamily KQT member 4

    go.drugbank.com/bio_entities/BE0002399
    TargetHumans

    Pore-forming subunit of the voltage-gated potassium (Kv) channel involved in the regulation of sensory cells excitability in the cochlea (PubMed:10025409, PubMed:34767770).

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 4Synonyms: Voltage-gated potassium channel subunit Kv7.4
  3. Target

    Potassium voltage-gated channel subfamily KQT member 5

    go.drugbank.com/bio_entities/BE0002400
    TargetHumans

    Pore-forming subunit of the voltage-gated potassium (Kv) channel broadly expressed in brain and involved in the regulation of neuronal excitability (PubMed:10787416, PubMed:10816588, PubMed:11159685, PubMed

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 5Synonyms: Voltage-gated potassium channel subunit Kv7.5
  4. Target

    Potassium voltage-gated channel subfamily A member 4

    go.drugbank.com/bio_entities/BE0004502
    TargetHumans

    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. … The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:19912772, PubMed:8495559).

    Polypeptides: Potassium voltage-gated channel subfamily A member 4Synonyms: Voltage-gated K(+) channel HuKII, Voltage-gated potassium channel HBK4
  5. Target

    Potassium voltage-gated channel subfamily A member 2

    go.drugbank.com/bio_entities/BE0004715
    TargetHumans

    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. … The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:11211111, PubMed:19912772, PubMed:23769686, PubMed:8495559).

    Polypeptides: Potassium voltage-gated channel subfamily A member 2Synonyms: Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel HBK5
  6. Target

    Potassium voltage-gated channel subfamily A member 3

    go.drugbank.com/bio_entities/BE0004716
    TargetHumans

    Mediates the voltage-dependent potassium ion permeability of excitable membranes. … Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with

    Polypeptides: Potassium voltage-gated channel subfamily A member 3Synonyms: Voltage-gated K(+) channel HuKIII, Voltage-gated potassium channel subunit Kv1.3
  7. Target

    Potassium voltage-gated channel subfamily A member 5

    go.drugbank.com/bio_entities/BE0004717
    TargetHumans

    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. … The channel alternates between opened and closed conformations in response to the voltage difference across the membrane.

    Polypeptides: Potassium voltage-gated channel subfamily A member 5Synonyms: Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv1.5
  8. Target

    Potassium voltage-gated channel subfamily A member 6

    go.drugbank.com/bio_entities/BE0004718
    TargetHumans

    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. … The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:14575698, PubMed:2347305).

    Polypeptides: Potassium voltage-gated channel subfamily A member 6Synonyms: Voltage-gated potassium channel HBK2, Voltage-gated potassium channel subunit Kv1.6
  9. Target

    Potassium voltage-gated channel subfamily A member 10

    go.drugbank.com/bio_entities/BE0004720
    TargetHumans

    Voltage-gated potassium ion channel that mediates K(+) permeability of excitable membranes. … When opened in response to the voltage difference across the membrane, KCNA10 channel selectively allows the flow of potassium ions across the membrane down their electrochemical gradient

    Polypeptides: Potassium voltage-gated channel subfamily A member 10Synonyms: Voltage-gated potassium channel subunit Kv1.8
  10. Target

    Voltage-dependent T-type calcium channel subunit alpha-1G

    go.drugbank.com/bio_entities/BE0000483
    TargetHumans

    T-type calcium channels belong to the 'low-voltage activated (LVA)' group and are strongly blocked by mibefradil. … A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation.

    Polypeptides: Voltage-dependent T-type calcium channel subunit alpha-1GSynonyms: Voltage-gated calcium channel subunit alpha Cav3.1