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Displaying results 1201 - 1210 of 10000 in total
  1. Drug

    Emicizumab

    go.drugbank.com/drugs/DB13923
    ApprovedInvestigational

    Emicizumab was originated as an improved form of hBS23 and it was approved on November 16, 2017.[A31279, L1016] It was created by Chugai Pharmaceuticals Co. … The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable hemostatic efficacy produced by previous Factor VII agents.

    Categories: Amino Acids, Peptides, and Proteins, Blood and Blood Forming OrgansProducts: HEMLIBRA 150MG/ML SOLUTION FOR INJECTION, HEMLIBRA SOLUTION FOR INJECTION 150MG/ML
  2. Drug

    Coenzyme M

    go.drugbank.com/drugs/DB09110
    ApprovedInvestigational

    Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]

    Mixtures: IFEX and MESNEX, IFEX and MESNEXCategories: Cough and Cold Preparations
  3. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.

    Mixtures: Dextrose and Electrolyte No. 75, Dextrose and Electrolyte No. 48Categories: Alimentary Tract and Metabolism, Blood and Blood Forming Organs
  4. Target

    Multidrug and toxin extrusion protein 2

    go.drugbank.com/bio_entities/BE0004752
    TransporterHumans

    Mediates the efflux of endogenous compounds such as, creatinine, thiamine and estrone-3-sulfate. … Plays a physiological role in the excretion of drugs, toxins and endogenous metabolites through the kidney

    Polypeptides: Multidrug and toxin extrusion protein 2
  5. Target

    Nucleolar and coiled-body phosphoprotein 1

    go.drugbank.com/bio_entities/BE0005819
    TargetHumans

    It has intrinsic GTPase and ATPase activities (PubMed:9016786) … processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).

    Polypeptides: Nucleolar and coiled-body phosphoprotein 1
  6. Target

    Cysteine and glycine-rich protein 1

    go.drugbank.com/bio_entities/BE0009098
    TargetHumans

    Could play a role in neuronal development

    Polypeptides: Cysteine and glycine-rich protein 1
  7. Target

    Sodium- and chloride-dependent taurine transporter

    go.drugbank.com/bio_entities/BE0009148
    TransporterHumans

    Taurine acts as an anti-aging agent by reducing cellular senescence and combating oxidative stress: levels decline with age and supplementation has been shown to extend lifespan (By similarity). … Can also mediate transport of beta-alanine, hypotaurine and gamma-aminobutyric acid (GABA) (PubMed:39837997, PubMed:40108165, PubMed:40789850, PubMed:41269860, PubMed:8010975)

    Polypeptides: Sodium- and chloride-dependent taurine transporter
  8. Target

    TRAF2 and NCK-interacting protein kinase

    go.drugbank.com/bio_entities/BE0009399
    TargetHumans

    MAP4Ks act in parallel to and are partially redundant with STK3/MST2 and STK4/MST2 in the phosphorylation and activation of LATS1/2, and establish MAP4Ks as components of the expanded Hippo pathway (PubMed … Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development.

    Polypeptides: TRAF2 and NCK-interacting protein kinase
  9. Drug

    Griseofulvin

    go.drugbank.com/drugs/DB00400
    ApprovedVet approved

    An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.

    Products: Grisovin Fp Tab 250mg, Grisovin-FP 250mg Tab
  10. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action.

    Mixtures: Aerius D-12 Modified Release Tablets 2.5mg/120mg, NEUMOLEX® NFCategories: Loratadine and derivatives, Histamine H1 Antagonists, Non-Sedating