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Displaying results 1201 - 1210 of 10000 in total
  1. Drug

    Selenium

    go.drugbank.com/drugs/DB11135
    ApprovedInvestigationalVet approved

    Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen

    Synonyms: SeInternational brands: B-Traxim Se
  2. Indication

    Back pain

    go.drugbank.com/conditions/DBCOND0115953
    Drugs: Acetaminophen · Borneol · Camphor · Capsaicin · Choline salicylate · Chondroitin sulfate +11 more
    Synonyms: Pain in back
  3. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: Levetiracetam in Sodium Chloride, KEPPRA 100MG/ML LSG Z EIN
  4. Drug

    Chlorpheniramine

    go.drugbank.com/drugs/DB01114
    ApprovedInvestigational

    A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. … One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.

    Mixtures: Benylin All-IN-one Cold & Flu Nighttime, Benylin for Children All-IN-one Cold & FeverCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  5. Drug

    Arginine

    go.drugbank.com/drugs/DB00125
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is physiologically active in the L-form.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseSynonyms: (S)-2-amino-5-guanidinopentanoic acid, (S)-2-Amino-5-guanidinovaleric acid
  6. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    found in clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold more potent than [atorvastatin]'s effects on LDL cholesterol. … [A181087, A181406] Rosuvastatin and other drugs from the statin class of medications including [atorvastatin], [pravastatin], [simvastatin], [fluvastatin], and [lovastatin] are considered first-line

    Mixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20Categories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  7. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). … Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.

    Synonyms: Phospholipase C-deleted in lung carcinoma
  8. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.

    Categories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AntagonistsSynonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-Azamianserin
  9. Drug

    Tyrosine

    go.drugbank.com/drugs/DB00135
    ApprovedInvestigationalNutraceutical

    Tyrosine is a non-essential amino acid. In animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.

    Mixtures: 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose, AMINOPLASMAL 15% IN 500ML GLASS BOTTLESynonyms: (S)-2-Amino-3-(p-hydroxyphenyl)propionic acid, (S)-3-(p-Hydroxyphenyl)alanine
  10. Target

    Gremlin-1

    go.drugbank.com/bio_entities/BE0011799
    TargetHumans

    Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). … Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback

    Synonyms: Increased in high glucose protein 2, Down-regulated in Mos-transformed cells protein