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Glimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalCompared to [glipizide], another second SU drug, glimepiride has a longer duration of action. … It is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs.
Mixtures: GLIMETAL-DP, METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesFezolinetant
go.drugbank.com/drugs/DB15669ApprovedInvestigationalWomen undergoing abrupt menopause due to oophorectomy also experienced more severe symptoms than those going through a gradual transition. … [A259542] Although previous NK3 receptor antagonists exist, such as osanetant and talnetant, only fezolinetant showed tangible effects on the HPC axis, potentially due to its favorable pharmacokinetics
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesLatanoprostene bunod
go.drugbank.com/drugs/DB11660ApprovedConversely however, latanoprostene bunod integrates an NO-donating moiety in lieu of the isopropyl ester typically found in latanoprost.
Tegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalTegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. … When converted and bioactivated to 5-FU, the drug mediates an anticancer activity by inhibiting thymidylate synthase (TS) during the pyrimidine pathway involved in DNA synthesis. 5-FU is listed on the
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesInternational brands: ESUEEW AN TRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedNutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ...
Synonyms: 6,7-Dimethyl-9-D-ribitylisoalloxazine, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazineMixtures: VIL-Rx, Vitamine Du Groupe B Plus Fer - LiqXylose
go.drugbank.com/drugs/DB09419ApprovedWithdrawnThe dextrorotary form of xylose, D-xylose, refers usually to the endogenously occurring form of the sugar in living things. The levorotary form, L-xylose, can refer to the form that is synthesized. … D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. Xylose has also been used as a diagnostic agent to observe malabsorption.
Synonyms: D-Xylose, aldehydo-D-xyloseVusolimogene oderparepvec
go.drugbank.com/drugs/DB23008ApprovedInvestigationalcells, causing tumor lysis and release of tumor and viral antigens, with the GALV-GP-R– glycoprotein enhancing direct tumor killing and GM-CSF promoting dendritic cell and monocyte activation to drive an … ] The FDA granted vusolimogene oderparepvec-wtpg accelerated approval on August 6, 2026, in combination with nivolumab for adults with unresectable advanced cutaneous melanoma that progressed on a PD
Galactose
go.drugbank.com/drugs/DB11735ApprovedInvestigationalWithdrawnRegardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products
Synonyms: D-Galactose, D(+)-GalactoseMixtures: Levovist - Pws IV (4g Granules /vial)Molindone
go.drugbank.com/drugs/DB01618ApprovedMolindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. … An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder.
Categories: Dopamine D2 Receptor AntagonistsGlecaprevir
go.drugbank.com/drugs/DB13879ApprovedInvestigationalIn cell cultures, the emergence of amino acid substitutions at NS3 resistance-associated positions A156 or D/Q168 in HCV genotype 1a, 2a or 3a replicons led to reduced susceptibility to glecaprevir [FDA … Mavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with regimens either containing an NS5A inhibitor or an NS3/4A protease inhibitor, but not both [L940].
Categories: P-glycoprotein inhibitors, P-glycoprotein substrates