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Displaying results 1221 - 1230 of 7181 in total
  1. Drug

    Oxygen

    go.drugbank.com/drugs/DB09140
    ApprovedInvestigationalVet approved

    an attempt to oxygenate the lungs. … ability to take up and use gaseous oxygen.

    Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 MixtureProducts: Oxygen Size T, N/A
  2. Indication

    Corneal injuries

    go.drugbank.com/conditions/DBCOND0026236
    Drugs: Prednisolone
    Synonyms: Scratch to cornea
  3. Indication

    Tuberculosis (TB)

    go.drugbank.com/conditions/DBCOND0035963
    Drugs: Amikacin · Aminosalicylic acid · BCG vaccine · Bacillus calmette-guerin substrain tice live antigen · Capreomycin · Cortisone acetate +7 more
    Synonyms: Infection due to Mycobacterium tuberculosis
  4. Drug

    Dabigatran etexilate

    go.drugbank.com/drugs/DB06695
    ApprovedInvestigational

    [A177463] In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022] … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor [dabigatran].

  5. Drug

    Pitolisant

    go.drugbank.com/drugs/DB11642
    ApprovedInvestigational

    In a European clinical trial of adult patients with narcolepsy, there was a reduction in the Epworth Sleepiness Scale (ESS) score from pitolisant therapy compared to placebo. … [A32024] The therapeutic effectiveness of pitolisant was comparable to that of [modafinil].

  6. Drug

    Piperazine

    go.drugbank.com/drugs/DB00592
    ApprovedVet approvedWithdrawn

    Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. … Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.

  7. Drug

    Hetacillin

    go.drugbank.com/drugs/DB00739
    ApprovedVet approvedWithdrawn

    Hetacillin has been withdrawn from the market since it has been discovered that it has no therapeutic advantage compared to non-ester derivatives like ampicillin. … The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins.

  8. Indication

    Salicylate intoxication

    go.drugbank.com/conditions/DBCOND0108398
    Drugs: Sodium bicarbonate
    Synonyms: Toxicity to various agents
  9. Drug

    Sebetralstat

    go.drugbank.com/drugs/DB18305
    ApprovedInvestigational

    Sebetralstat is the first and only oral on-demand treatment for HAE, providing a convenient alternative to injectable therapies that have been challenging for patients to use [L53538, A274293]. … This plasma kallikrein inhibitor works by reducing bradykinin, the substance that causes the characteristic swelling in HAE attacks [L53533]. The U.S.

    Synonyms: 1H-Pyrazole-4-carboxamide, N-[(3-fluoro-4-methoxy-2-pyridinyl)methyl]-3-methoxymethyl)-1-[[4-[(2-oxo-1(2H)-pyridinyl)methyl]phenyl]methyl]-, N-[(3-fluoro-4-methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1(2H)-yl)methyl]phenyl}methyl)-1H-pyrazol-4-carboxamide
  10. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous Factor Xa. … The amino acid residue modification from serine to alanine in the binding site of the catalytic domain allows more effective binding to FXa inhibitors and deters the andexanet alfa from converting prothrombin