Tuberculosis (TB) (DBCOND0035963)

Identifiers

Synonyms
Tuberculosis (TB) Infection / TB - Tuberculosis / Tuberculosis / Tuberculosis Infection / Tuberculous infections / TB / Tuberculosis (disorder) / Tuberculosis NOS / Infection TBC / Infection tuberculosis / Infection caused by Mycobacterium tuberculosis (disorder) / Tuberculous (qualifier value) / Transmitted by (attribute)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amikacin
An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
Aminosalicylic acid
An aminosalicylate drug used to induce remission in ulcerative colitis.
BCG vaccine
A vaccine indicated in the prevention of tuberculosis and the treatment of non-invasive urothelial bladder cancer.
No drug targets
Bacillus calmette-guerin substrain tice live antigen
A live attenuated vaccine against Mycobacterium bovis.
No drug targets
Capreomycin
An aminoglycoside antibiotic used as an adjunct drug in tuberculosis.
Cortisone acetate
A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Pretomanid
Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis.
Protionamide
An antitubercular thioamide-derivative used in the treatment of multi-drug resistant (MDR) tuberculosis and leprosy.
Rifabutin
An antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
Rifampin
An antibiotic used alone or in combination with other antimicrobial drugs to treat tuberculosis and asymptomatic carriers of Neisseria meningitidis.
Streptomycin
An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
Triamcinolone
A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Tuberculin purified protein derivative
A purified protein used in the Mantoux test for Mycobacterium tuberculosis testing.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03187964
Xpert Ultra and Xpert HIV-VL in People Living With HIVNo drug interventionsdiagnosticNot Availablecompleted
NCT06511180
Introduction of Dispersible 3HP Formulations for TB Preventive Treatment in Children: a Multi-country EvaluationNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04700579
Pre- and Post-treatment Lung Microbiota, Metabolome and Immune Signatures at the Site of Disease in Patients With Active Pulmonary TuberculosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT06314386
Systems Analysis and Improvement Approach to Prevent TBNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT04412239
To Assess the Efficiency and Satisfaction of Pharmacist Giving Patient-centred Advice on Telephone Consultation in TB Patients: Experience of the COVID-19 PandemicNo drug interventionsotherNot Availableunknown_status
NCT06613919
Six-months Versus Nine-months ATT for Ocular TBtreatment4completed
NCT04333485
Tuberculosis (TB) AftermathNo drug interventionsscreeningNot Availablerecruiting
NCT01875952
Diagnosis and Treatment of Co-infection With Human Immunodeficiency Virus /Latent Tuberculosis Infection (HIV/TBL)prevention4unknown_status
NCT03808636
Innovative Reagents for Improving Rapid Diagnosis of Mycobacterial InfectionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01879163
Phase I Trial Evaluating Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in BCG Vaccinated Adultsprevention1completed
NCT06484530
Gene-guided N-acetyl Cysteine for Prophylaxis of Anti-tuberculous Drug- Induced Hepatitisprevention4recruiting
NCT00291889
Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02 in Healthy PPD-negative Adults.No drug interventionsprevention1completed
NCT00146744
Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02A in Healthy PPD-positive AdultsNo drug interventionsprevention2completed
NCT06272812
A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in IGRA Positive Adolescents and Adults Living in a TB Endemic Region.No drug interventionsprevention2not_yet_recruiting
NCT03929705
Assessing the Ability of the T-SPOT®.TB TestNo drug interventionsNot AvailableNot Availablecompleted
NCT00600782
Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Regionprevention2completed
NCT04243031
QuantiFERON Access Clinical Performance Study ProtocolNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00730795
Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine Given to PPD-Negative AdultsNo drug interventionsprevention1completed
NCT06253715
Shortened Regimen for Drug-susceptible TB in Childrentreatment3not_yet_recruiting
NCT01212003
Training Protocol on the Natural History of TuberculosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT03896750
Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Functiontreatment1recruiting
NCT04985994
Potential Role of Microbiome in TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT05007821
Linezolid Dosing Strategies in Drug-Resistant TBtreatment2active_not_recruiting
NCT05526911
A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adultstreatment1completed
NCT05686356
A Pan-TB Regimen Targeting Host and Microbetreatment2 / 3recruiting
NCT06618573
Safety of Administering Isoniazid to SLE Patients to Prevent TBprevention2 / 3recruiting
NCT03089983
Addiction, HIV and Tuberculosis in Malaysian Criminal Justice Settingshealth_services_researchNot Availablecompleted
NCT04052022
Paradoxical Tuberculosis Reactions in Patients Without HIV InfectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04567368
TB-CAPT MTB/XDR StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04568954
TB-CAPT CORE Truenat TrialNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT04568967
TB-CAPT EXULTANT - HIVNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT04926922
PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in LiberiaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05342064
Closing -TB GAPs - for People Living with HIV: TB Guidance for Adaptable Patient-Centered ServiceNo drug interventionsotherNot Availablerecruiting
NCT05724212
Evaluation of a CD4/CD8+ Interferon Gamma Release Assay for Monitoring Anti-Tuberculosis TreatmentNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05868005
Delivering a Multi-disease Screening Tool to Migrant PopulationsNo drug interventionsscreeningNot Availablerecruiting
NCT06062238
Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and AdultsNo drug interventionstreatment3recruiting
NCT06306430
Detection of Lipoarabinomannan in Urine Evaluation of the STANDARDTMF TBLAMFIA and Its Impact on the Initial TB DiagnosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06401434
Evaluation of CAD-based Triage for CXR Interpretation During TB ScreeningNo drug interventionsscreeningNot Availablerecruiting
NCT06593080
The DECIDE-TB Trial; Validation of Treatment Decision Algorithms for Childhood TuberculosisNo drug interventionsdiagnosticNot Availablerecruiting
NCT02281643
Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghanaprevention2completed
NCT06403943
Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosistreatment4recruiting
NCT01864603
Sustainable East Africa Research in Community HealthNo drug interventionsotherNot Availablecompleted
NCT01071603
Tuberculosis in ChinaNo drug interventionsNot AvailableNot Availablecompleted
NCT04972903
Impact of Malnutrition on Pharmacokinetic or Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children (TB-Speed TB-PK)No drug interventionsNot AvailableNot Availablecompleted
NCT03199690
A Clinical Study Investigating Rifampicin and Dolutegravir in Combination in Healthy Volunteerstreatment1unknown_status
NCT00608790
Rapid Diagnosis of Pulmonary TuberculosisdiagnosticNot Availableunknown_status
NCT00990990
Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult VolunteersNot Available1completed
NCT01829490
Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adultsprevention1completed
NCT05118490
Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patientsprevention4recruiting
NCT01868464
Challenge Model for Assessment of Human TB ImmunityNo drug interventionsprevention1completed
NCT01742364
Comparative Study of Bacille Calmette Guerin (BCG) Delivery Via Disposable Syringe Jet Injector and Needle & SyringeNo drug interventionspreventionNot Availablecompleted
NCT00173264
Immunologic and Genetic Characteristics of Monoclonal Immunoglobulins in Patient With TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT04777721
Aerosol BCG Challenge Study in Historically BCG-vaccinated VolunteersNo drug interventionsother1unknown_status
NCT01119521
Study of Pre-clearance of Latent Tuberculosis Infection And BCG Revaccinationtreatment1completed
NCT02501421
Reactogenicity, Safety and Immunogenicity of a TB/FLU-04L Tuberculosis Vaccineprevention1completed
NCT00057421
Tuberculosis in HIV Infected Patients in Ugandatreatment2completed
NCT03665402
A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism StatuspreventionNot Availablecompleted
NCT04151602
Transmission of Tuberculosis Among Illicit Drug Use LinkagesNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00802802
Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Childrentreatment1completed
NCT00793702
Safety and Risk of Sensitisation of the rdESAT-6 + rCFP-10 Skin Test Following Repeated Intradermal AdministrationNo drug interventionsdiagnostic1completed
NCT05989802
Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)No drug interventionsdiagnosticNot Availablerecruiting
NCT01779102
Safety Study Investigating if Concomitant Injections of C-Tb and 2 T.U Tuberculin Affect Induration Responsesdiagnostic2 / 3completed
NCT00857402
Arginine as an Adjuvant Treatment Against TuberculosisNo drug interventionssupportive_careNot Availablecompleted
NCT05655702
DRug Use & Infections in ViEtnam: TuBerculosis ControlNo drug interventionsscreeningNot Availablerecruiting
NCT06437184
Increased Tuberculosis Case Detection - DiOpTBNo drug interventionsdiagnosticNot Availablerecruiting
NCT01341184
TMC207 +/- Rifabutin/Rifampintreatment1completed
NCT05330884
BCG Revaccination in Children and Adolescentsprevention3suspended
NCT01554384
Trial of Point-of-treatment Xpert MTB/RIF AssayNo drug interventionsdiagnosticNot Availablecompleted
NCT02581579
Study to Evaluate the Tolerability and Immunogenicity of Nyaditum Resae ® Probiotic Administered to Pediatric Population in Contact With Tuberculosis With or Without Latent Tuberculosis InfectionNo drug interventionspreventionNot Availablecompleted
NCT01926379
ENhance Initiation and Retention in Isoniazid Preventive Therapy (IPT) Care for HIV Study (ENRICH Study)otherNot Availablecompleted
NCT00397943
Safety and Immunogenicity of 2 Formulations of Tuberculosis Vaccine GSK692342 Given at 0,1 Months to Healthy AdultsNo drug interventionsprevention2completed
NCT01832987
Pharmacokinetic Parameters of Co-trimoxazoleNot Available2completed
NCT01800487
The Efficacy of Silymarin on the Prevention of Hepatotoxicity From Antituberculosis DrugspreventionNot Availablecompleted
NCT01390987
Access to Care and Adherence Tuberculosis (TB) SurveyNo drug interventionsNot AvailableNot Availablecompleted
NCT00023387
TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl RifapentinetreatmentNot Availablecompleted
NCT06284187
Diagnosis Test of Real-time Polymerase Chain Reaction (RT-PCR) for Pulmonary TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00001033
The Treatment of Tuberculosis in HIV-Infected Patientstreatment3completed
NCT00491933
Quantiferon-TB Gold in the Assessment of Latent TB in Patients Candidate to Treatment or Treated With TNFα AntagonistsNo drug interventionsdiagnosticNot Availableunknown_status
NCT00568854
Immunobiology of Diabetes and Tuberculosisbasic_scienceNot Availableterminated
NCT02115854
Labial Biopsy in Patients With Tuberculosis DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00483054
Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving Rifampintreatment3completed
NCT05259254
Effectiveness Of Mobile Application To Improve Adherence To Tuberculosis TreatmentNo drug interventionspreventionNot Availablerecruiting
NCT00932854
A Clinical tRial of Endobronchial Ultrasound for the Diagnosis of MEDiastinal lymphadenopathY (REMEDY)No drug interventionsdiagnosticNot Availableunknown_status
NCT01131351
Safety and Pharmacokinetics (PK) in Multidrug-Resistant (MDR) Refractive Tuberculosistreatment2terminated
NCT05472051
Health and Migration Trajectories of Housekeepers in BamakoNo drug interventionsNot AvailableNot Availablecompleted
NCT05406453
Whole Genome Sequencing of Tuberculosis for Disease Control in MadagascarNo drug interventionsdiagnosticNot Availablerecruiting
NCT00427453
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Received BCG Immunisation 1 Month Previouslyprevention1completed
NCT01635153
Effects of a Protein Calorie Supplement in HIV-infected Women With TuberculosisNo drug interventionstreatmentNot Availablecompleted
NCT02840877
The Impact of Alcohol Consumption on Tuberculosis Treatment OutcomesNo drug interventionssupportive_careNot Availablecompleted
NCT03982277
Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapytreatment2completed
NCT02953847
The Bioavailability of Rifampicin in (FDCs) Widely Used in South Africa to Treat Drug-susceptible (TB)other1completed
NCT06522347
Mycobacteria Registry Study: Prospective Observational Study in AustriaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00242047
Randomized Controlled Trial of Percutaneous and Intradermal BCG Vaccination.prevention4unknown_status
NCT00078247
Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosistreatment3completed
NCT02021747
Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium TuberculosisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05317247
Cough Audio Classification as a TB Triage TestNo drug interventionsNot AvailableNot Availablerecruiting
NCT03168945
Xpert Active Case-finding Trial 2: Community-based Active Case-finding for Tuberculosis in South AfricaNo drug interventionsscreeningNot Availablecompleted
NCT02013245
Dose-Escalation Study to Evaluate the Safety and Immunogenicity of MTBVAC Vaccine in Comparison With BCG Vaccine.prevention1completed
NCT02681445
Non-invasive TB Triage and Patient Mapping Platform Using Breath Via Low-Cost Titanium Dioxide Nanotube SensorNo drug interventionsNot AvailableNot Availablecompleted
NCT01755598
Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in AdultsNo drug interventionsprevention2completed
NCT01422798
An Open Cohort of Childhood Tuberculosis in Mbarara National Referral Hospital, UgandaNo drug interventionsNot AvailableNot Availablecompleted
NCT00311298
Nutrition, Diabetes and Pulmonary TB/HIVNo drug interventionstreatment3completed
NCT05116098
Randomized Clinical Trial: IS Zinc and Zinc Ionophere EGCG as Supplement Improve Outcome of Active Pulmonary Tuberculosistreatment1unknown_status
NCT02252198
Evaluation of Non-Inferiority of Two Fast Follower Nucleic Acid Amplification TestsNo drug interventionsNot AvailableNot Availablecompleted
NCT01099098
Prevalence of Latent Tuberculosis (TB) Infection Diagnosed by Interferon-gamma Release Assay and Tuberculin Skin Tests in Patients With Old Healed TBNo drug interventionsNot AvailableNot Availablecompleted
NCT03948698
TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI)No drug interventionsNot AvailableNot Availablecompleted
NCT05610098
Gene Expression Profiles in Spinal Tuberculosis.No drug interventionsNot AvailableNot Availablerecruiting
NCT02238405
A Controlled Smoking Cessation Trial and Prospective Cohort Study of Tuberculosis (TB) Treatment OutcomesNo drug interventionstreatmentNot Availablecompleted
NCT01539005
Tuberculosis Recurrence Upon Treatment With Highly Active Antiretroviral TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT04285905
Male Partner-assisted Contact Tracing for HIV and Tuberculosis in MalawiNo drug interventionshealth_services_research2 / 3terminated
NCT01685905
The Usefulness of Interferon-γ Release Assays and Tuberculin Skin Test for Detection of Latent Tuberculosis InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02454205
An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosistreatment2 / 3completed
NCT00647205
Evaluation of 2 Interferon γ Assays in the Diagnosis of Latent Tuberculosis in HIV-infected Patients.ANRS EP 40 QUANTI SPOTNo drug interventionsdiagnostic4completed
NCT04472897
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult ParticipantsNo drug interventionstreatment1recruiting
NCT02127983
Engaging Informal Health Care Providers on Case Detection and Treatment Initiation Rates for TB and HIV in Rural Malawi (Triage Plus)No drug interventionshealth_services_researchNot Availablecompleted
NCT06585683
Post-Trial Tuberculosis Case Finding: a Substudy of CoVPN 3008 (Ubuntu)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00266383
The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT00174083
Diagnosis of Active Tuberculosis by ELISPOTNo drug interventionsNot AvailableNot Availableunknown_status
NCT00172783
PPD Size and Mycobacteria Tuberculosis ELISPOT in Children Who Have Received BCG in Neonate PeriodNo drug interventionsNot AvailableNot Availableunknown_status
NCT01545661
Utility of Sputum Induction and Novel Technologies to Improve TB Diagnosis in a High HIV Prevalence Primary Care SettingNo drug interventionsdiagnosticNot Availablecompleted
NCT03870061
Evaluation of an Infant Immunization Encouragement Program in NigeriaNo drug interventionspreventionNot Availablecompleted
NCT06113861
Diagnostic Innovations for Pediatric Tuberculosis in BoliviaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01136161
Clinical Trial to Investigate the Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI® Following One Month of Isoniazid Treatment in Subjects With Latent Tuberculosis InfectionNo drug interventionstreatment2completed
NCT03862261
Integrating Pediatric TB Services Into Child Healthcare Services in AfricaNo drug interventionsdiagnosticNot Availablecompleted
NCT00675961
Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, RussiatreatmentNot Availablecompleted
NCT03881228
Patient Centered Intervention to Prevent Tuberculosis Among Children Under Five Years OldNo drug interventionspreventionNot Availablecompleted
NCT00293228
Treatment of Latent Tuberculosis Infection With Isoniaziddiagnostic4completed
NCT02414828
A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TBNo drug interventionsprevention2completed
NCT00341328
Efficacy and Safety of Immunomodulator as an Adjunct Therapy in New Pulmonary Tuberculosis(Category I) Patients.treatment3completed
NCT04242511
Tuberculosis Drug Levels in DiabeticsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05542511
Host Blood RNA Signatures for Diagnosis of TBNo drug interventionsNot AvailableNot Availablerecruiting
NCT01331811
Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon)No drug interventionsdiagnosticNot Availablecompleted
NCT03993093
Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART CentreNo drug interventionsNot AvailableNot Availablecompleted
NCT05364593
Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01003093
A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis(TB) Subunit VaccineNo drug interventionsprevention1completed
NCT01061593
Adjunct Immunotherapy With Immunoxel in Patients With TB and TB/HIVNo drug interventionstreatment3completed
NCT00981071
The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis ExposureNo drug interventionsNot AvailableNot Availablecompleted
NCT04593771
Phase I Clinical Protocol of BCG-PPD in Healthy PeopleNo drug interventionsdiagnostic1completed
NCT04493671
Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adultstreatment1completed
NCT03363178
Study to Investigate the Safety and Efficacy of GC3107 (BCG Vaccine) in Healthy AdultsNo drug interventionsprevention1unknown_status
NCT03736278
Characteristics of Tuberculosis Infection in Rheumatic DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02236078
Brief Bactericidal Activity of Anti-Tuberculosis Drugstreatment1completed
NCT05124678
Pharmacogenetics-guided Isoniazid Dosing in TB-HIVtreatment2unknown_status
NCT01560078
Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural EffusionNo drug interventionsNot AvailableNot Availablecompleted
NCT03017378
Reactogenicity, Safety and Immunogenicity of a TB/FLU-01L Tuberculosis VaccineNo drug interventionstreatment1completed
NCT04975178
Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africaprevention3recruiting
NCT06221488
Testing Health Workers At Risk to Advance Our Understanding of TB InfectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT01642888
A Trial in Subjects Suspected to Have Tuberculosis, Comparing the Diagnostic Performance of C-Tb to QuantiFERON®, in Combination With a Safety Assessment of C-Tb Versus Tuberculin PPD RT23 SSIdiagnostic3completed
NCT03851588
Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosistreatment2completed
NCT00595907
Results of an Interferon-Gamma Release Assay After Treatment for TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT06033807
Active Screening of Latent Tuberculosis Infection in School Contacts of Active Tuberculosis PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02378207
Safety and Immunogenicity Study of BCG, H4:IC31, and H56:IC31 Revaccination in Healthy Adolescentsprevention1completed
NCT03800407
Contributing Factors for Poor HIV Treatment Response in Children With TB/HIV CoinfectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03912207
Investigating Immune Responses to Aerosol BCG Challenge in Healthy UK AdultsNo drug interventionsother1active_not_recruiting
NCT02382107
A Blinded, Cross-sectional, Diagnostic Evaluation Study Performed in Pulmonary TB Suspects at the TB Dispensary for Sector 4 of the Marius-Nasta-Institute in Bucharest, RomaniaNo drug interventionsNot AvailableNot Availablecompleted
NCT05840809
Pharmacokinetics of Drugs Used to Treat Drug Sensitive Tuberculosis in Breastfeeding Mother-infant PairsNot AvailableNot Availableactive_not_recruiting
NCT04826809
New Reusable Mask Design With Superior Filtration and FitNo drug interventionspreventionNot Availablecompleted
NCT00397709
Short-Course Isoniazid and Rifampin Compared With Isoniazid for Latent Tuberculosis Infectiontreatment4terminated
NCT02074956
A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 Administered in AdultsNo drug interventionsprevention1completed
NCT01181856
Safety of Tuberculosis Vaccine, MVA85A, Administered by the Intramuscular Route and the Intradermal Routeprevention1completed
NCT05526885
Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South AfricaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00000785
A Registry of Tuberculosis Cases in the CPCRANo drug interventionsNot AvailableNot Availablecompleted
NCT01450085
Chepetsa TB - Reducing TB Among HIV-Infected MalawiansNo drug interventionsotherNot Availablecompleted
NCT02391415
Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africaprevention2completed
NCT00822315
Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosistreatment2completed
NCT00850915
Feasibility and Effectiveness of Community Based Isoniazid Preventive Therapy in KenyaNo drug interventionsprevention4completed
NCT02253537
Evaluation of the QuantiFERON-TB Test.No drug interventionsNot AvailableNot Availablecompleted
NCT04975737
Study of the Safety and Efficacy of the Subunit Recombinant Tuberculosis Vaccine GamTBvacNo drug interventionsprevention3recruiting
NCT00005737
Tuberculosis Prophylaxis in the Homeless--A Controlled TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT02331732
Virtually Observed Treatment (VOT) for Tuberculosis Patients in MoldovaNo drug interventionssupportive_careNot Availableunknown_status
NCT00023452
Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infectionprevention3completed
NCT05236452
Effect of Integrating Traditional Tuberculosis Care With Modern Health Care on Case DetectionNo drug interventionstreatmentNot Availablecompleted
NCT02538952
Evaluating Accuracy, Impact, and Operational Challenges of GeneXpert Use for TB Case Finding Among HIV-infected PersonsNo drug interventionsdiagnostic4completed
NCT06019052
Evaluating Next Generation LAM Assays and Molecular Diagnostics (POC and Near POC) for the Diagnosis of TB Among People With Presumptive TB: a Prospective Multicentre Diagnostic Accuracy StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00023400
TBTC Study 23B:Intensive PK of the Nelfinavir Rifabutin Interaction in Patients With HIV-TBtreatment4completed
NCT03590600
A Single Ascending Dose Study of BTZ043treatment1completed
NCT00679159
A Study of MVA85A in Healthy Children and Infantsprevention2completed
NCT04709159
Impact of Mobile Health Interactive Software on Tuberculosis Outcomes; The Call for Life (CFLU-TB) ProjectNo drug interventionssupportive_careNot Availableunknown_status
NCT01182259
The Incidence and Risk Factors of Side Effects During the Initial Phase of Rifater Therapy - a Prospective StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02430259
Efficacy of Weekly Rifapentine and Isoniazid for Tuberculosis Preventionprevention3completed
NCT05818059
Active Close Contact Investigation of Tuberculosis Through Computer-aided Detection and Stool Xpert MTB/RIF Among People Living in EthiopiaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT04947475
Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the CommunityNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT00767975
Active Screening of Latent TB Infection, Treatment and Long Term Follow-up in Prisontreatment3completed
NCT01601275
Database of All Patients With Microbiologically Proven Mycobacteria Tuberculosis InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01242475
A Trial of the C-Tb Skin Test, When Given Intradermally to Healthy Volunteers Previously Vaccinated With BCGdiagnostic2completed
NCT04119375
Behavior Change and Digital Health Interventions for Improved TB Treatment OutcomesNo drug interventionstreatmentNot Availablecompleted
NCT04703075
Ultra Curto (Ultra Short) TB Prevention Therapyprevention4completed
NCT03137875
Evaluation of PCR Using DNA Extract From Slides and Filter Paper for the Detection of Tuberculosis and MDR-tuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00743470
A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult Subjectstreatment1terminated
NCT00653770
A Phase I Study to Assess the Safety and Immunogenicity of Tuberculosis (TB) Vaccine Candidates FP85A and MVA85Aprevention1completed
NCT00396370
BCG Vaccination Delivered Intradermally, Orally and by Combined Routesprevention1completed
NCT02845570
Evaluation of Somatostatin Receptor Imaging Using PET/MRI as a Novel Approach to Detecting Pathology in Pulmonary TBNo drug interventionsother1unknown_status
NCT03973970
Assessing the Ability of the T-SPOT®.TB Test (IQ)No drug interventionsNot AvailableNot Availablecompleted
NCT02387242
Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteerstreatment1suspended
NCT03598842
Tuberculosis - Learning the Impact of Nutritionbasic_scienceNot Availableactive_not_recruiting
NCT03667742
Diagnosing of Acute TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00564642
Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver ToxicitypreventionNot Availablecompleted
NCT00341042
Collection of Tissue Specimens in Mali, West Africa, for HIV and Tuberculosis ResearchNo drug interventionsNot AvailableNot Availableterminated
NCT00005742
Behavioral Interventions for Control of TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03302299
Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)other4completed
NCT05249699
The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney TransplantationpreventionNot Availableunknown_status
NCT03806699
Phase 1 Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Adolescentprevention1unknown_status
NCT04916899
Safety of doTBal® in Patients With Tuberculosis: Conduction of an Intensive Pharmacovigilance ProgramNot AvailableNot Availablecompleted
NCT03074799
Nurse-Led, Symptom-Based Screening of Household Child Contacts of Tuberculosis Index CasesNo drug interventionspreventionNot Availablecompleted
NCT00801606
Micronutrient Supplementation in in Paediatric Pulmonary Tuberculosistreatment3completed
NCT00128206
Treatment of Latent TB Infection for Jailed Personstreatment3completed
NCT00925249
Comparison of the Tuberculin Skin Test (TST) and QuantiFERON ®-TB Gold Test (QFT-G) In Patients With Rheumatoid Arthritis Being Considered for Anti-TNF-Alpha TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00129649
Service Development: Assessing Non-attendance Rates in Outpatient ClinicsNo drug interventionshealth_services_researchNot Availablecompleted
NCT03739736
TB Reduction Through ART and TB Screening ProjectNo drug interventionsNot AvailableNot Availableunknown_status
NCT04865536
Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjectstreatment1completed
NCT04734236
Development of Molecular Diagnostic Platform for TuberculosisNo drug interventionsdiagnosticNot Availableunknown_status
NCT01585636
Escalating Single-dose Safety, Tolerability, and Pharmacokinetics of SQ109 in Healthy Volunteerstreatment1completed
NCT00000636
Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous InfectiontreatmentNot Availablecompleted
NCT04520113
Kharituwe TB Contact Tracing StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT04187313
Increasing Notifications of Tuberculosis From Private PractitionersNo drug interventionshealth_services_researchNot Availablecompleted
NCT05077813
Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19treatment2unknown_status
NCT04015713
Lowering InterLeukin-1 Receptor Antagonist Concentrations After TB Treatment OnsetNo drug interventionsNot AvailableNot Availableunknown_status
NCT00023413
TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily Efavirenztreatment2completed
NCT01674218
Effect of PA-824 and of PA-824 Plus Moxifloxacin on the QTc Interval in Healthy Volunteerstreatment1completed
NCT00306319
Pharmacokinetic Interaction Study in Indonesian Tuberculosis Patients Indonesiatreatment2completed
NCT02170441
Global Consortium for Drug-resistant Tuberculosis DiagnosticsNo drug interventionsNot AvailableNot Availablecompleted
NCT00005741
Indigenous Outreach Among Injection Drug Users to Treat and Control TBNo drug interventionsNot AvailableNot Availablecompleted
NCT02169141
Pharmacokinetics of Levofloxacin and Capreomycin in Multidrug-Resistant Tuberculosis PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05174741
Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01322841
Universal Screening for Tuberculosis and Anemia With the CHICA SystemNo drug interventionsdiagnosticNot Availablecompleted
NCT01705041
Preliminary Evaluation of a Point-Of-Care Liver Function TestNo drug interventionsdiagnosticNot Availablecompleted
NCT00285441
Identification of Cytokine Profiles and T Cell Subsets Among Immunosuppressed Patients at Risk of Developing Active TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03536117
Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African NeonatesNo drug interventionsprevention2completed
NCT00698334
Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosistreatment3completed
NCT00226434
Early vs Late Introduction of Antiretroviral Therapy in HIV-infected Patients With Tuberculosis (ANRS 1295 CAMELIA)No drug interventionstreatment3completed
NCT06054334
Relevance of Isoniazid Dosage in Adults Treated for TuberculosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT02422524
Pretomanid in Adults With Hepatic Impairmenttreatment1terminated
NCT02712424
DAR-901 TB Booster Vaccine to Prevent TB in AdolescentsNo drug interventionsprevention2completed
NCT01021124
Latent Tuberculosis Infection in Bone Marrow Transplant RecipientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04593524
The Role of Vitamin D, A, and Beta Carotene in Tuberculosis Patients With Vitamin D Receptor Gene PolymorphismNo drug interventionsdiagnosticNot Availablecompleted
NCT00857116
Deworming Against Tuberculosissupportive_careNot Availablecompleted
NCT03507816
A Multidrug-resistant (MDR) and Extensively Drug- Resistant (XDR) Tuberculosis Study in AlsaceNo drug interventionsNot AvailableNot Availableunknown_status
NCT02874716
Quality of Tuberculosis Care in Urban Patna, IndiaNo drug interventionshealth_services_researchNot Availablecompleted
NCT04938596
Airborne Preventive Measures to Reduce New TB Infections in Household ContactsNo drug interventionspreventionNot Availablecompleted
NCT01722396
Pharmacogenetics of Vitamin D Supplementation in TuberculosisNo drug interventionstreatment3completed
NCT01669096
Study in Healthy Adults to Evaluate Gene Activation After Vaccination With GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342No drug interventionsother2completed
NCT05100758
Active Hexose Correlated Compound in Tuberculosis-HIV (Human Immunodeficiency Virus) InfectionNo drug interventionstreatmentNot Availablecompleted
NCT01637558
Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study)treatment4completed
NCT00523458
A Study to Determine the Best Dose of Antivirals in Patients With Both TB and HIVtreatment4terminated
NCT05571735
Immunogenicity of COVID-19 Vaccines in Tuberculosis PatientsNot AvailableNot Availableenrolling_by_invitation
NCT04525235
Phenotyping of High Dose Rifampicinother1completed
NCT04890535
Evaluation of the Safety, Tolerability, PK of TBAJ-587 in Healthy AdultsNo drug interventionstreatment1completed
NCT05337163
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaNo drug interventionsNot AvailableNot Availablecompleted
NCT00164463
TBTC Study 27/28 PK: Moxifloxacin Pharmacokinetics During TB Treatmenttreatment2completed
NCT00918086
Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to TreatmentNo drug interventionssupportive_care2completed
NCT03086486
Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosistreatment3completed
NCT00463086
Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected PersonspreventionNot Availablecompleted
NCT00929786
Anti-tuberculosis (TB) Drug Levels and HepatotoxicityNo drug interventionsNot AvailableNot Availablecompleted
NCT00023439
TBTC NAA Study: Pilot Study of Surrogate Markers for Outcome of TB TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02701439
SMF to Improve Performance of Microscopy for the Diagnosis of PTB in a High HIV Prevalence SettingNo drug interventionsNot AvailableNot Availablecompleted
NCT03199339
A Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371treatment1completed
NCT02076139
Safety and Immunogenicity of Nyaditum Resae® Probiotic to Protect From TuberculosisNo drug interventionspreventionNot Availablecompleted
NCT06347939
Mediastinal EBUS Cryobiopsy Study In SwedenNo drug interventionsNot AvailableNot Availablerecruiting
NCT02512939
Predictive Values of Next Generation Interferon Gamma Release Assays for Latent Tuberculosis InfectionNo drug interventionsdiagnosticNot Availablecompleted
NCT02503839
Therapeutic Vaccination and Immune Modulation - New Treatment Strategies for the MDR Tuberculosis Pandemictreatment1completed
NCT00621322
Safety and Immunogenicity Study of GSK Biologicals Tuberculosis Vaccines (692342) to Healthy Adultsprevention2completed
NCT01836822
Bronchoscopic Sampling Techniques in SarcoidosisNo drug interventionsdiagnosticNot Availableunknown_status
NCT01517022
Intensive Smoking-cessation Intervention Versus Smoking-cessation Advice in Smear-positive Patients With Pulmonary Tuberculosissupportive_care3completed
NCT00057122
Tuberculosis Prevention for HIV Infected Adultsprevention3completed
NCT00130325
A Trial of Isoniazid for the Reversion of Interferon Gamma ELISPOT in Tuberculosis (TB) Case ContactstreatmentNot Availablecompleted
NCT01038830
QuantiFERON Change During Anti-tuberculosis MedicationNo drug interventionsNot AvailableNot Availablecompleted
NCT00851630
Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST)treatment4completed
NCT00317330
A Randomized Trial of DOTS Versus Enhanced DOTS for Community Control of Tuberculosistreatment3completed
NCT01770730
A Trial of the Urine LAM Strip Test for TB Diagnosis Amongst Hospitalized HIV-infected PatientsNo drug interventionsdiagnosticNot Availablecompleted
NCT05586230
Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosistreatment1recruiting
NCT02329730
Phase IIa Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10diagnostic2completed
NCT01861730
Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infantsprevention1 / 2completed
NCT03423030
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulationtreatment1completed
NCT01766830
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)No drug interventionsdiagnosticNot Availablecompleted
NCT00149448
Effectiveness of the TB Contact Priority ModelNo drug interventionsNot AvailableNot Availablecompleted
NCT04874948
Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatmenttreatment1completed
NCT05640648
Human-centered Design and Communities of Practice to Improve Delivery of Home-based Tuberculosis Contact Investigation in UgandaNo drug interventionsscreeningNot Availablecompleted
NCT06141148
Clinical Presentation, and Treatment Outcomes in Tuberculous Patients in Sohag GovernorateNo drug interventionsNot AvailableNot Availablerecruiting
NCT02583048
Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosistreatment2completed
NCT01748357
Siemens VOC TB Pilot StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06354257
A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of AgeNo drug interventionsprevention1recruiting
NCT01424826
The Effect of Intermittent Rifampicin on Raltegravirtreatment1completed
NCT05865626
Evaluation of the VOT Among Tuberculosis Patients From LambarénéNo drug interventionsotherNot Availablecompleted
NCT01601626
Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIVtreatment2terminated
NCT00551226
Follow up of Autoantibodies in Active TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00523926
TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosistreatment2completed
NCT00865826
Observational Study of Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected IndividualsNo drug interventionsNot AvailableNot Availablecompleted
NCT03915366
Empirical Treatment Against Cytomegalovirus and Tuberculosis in HIV-infected Infants With Severe Pneumoniatreatment2 / 3active_not_recruiting
NCT00313066
Comparison the Level of CTGF Protein and Related Cytokine in Pleural EffusionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00157066
Effects of Vitamin D Supplementation on Antimycobacterial ImmunityNot AvailableNot Availablecompleted
NCT00465465
A Study of 2 Doses of a New TB Vaccine, MVA85A, in Healthy Volunteers Previously Vaccinated With BCGprevention1completed
NCT06497465
Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatmenttreatment3not_yet_recruiting
NCT02913365
Etiologies, Investigations and Outcomes of Patients Presenting With HemoptysisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00023374
TBTC Study 24: Intermittent Treatment of TB With Isoniazid Resistance or IntolerancetreatmentNot Availablecompleted
NCT01350674
Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph NodesNo drug interventionsdiagnosticNot Availablesuspended
NCT02109874
A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 (C-011-404)prevention1completed
NCT02875574
Improving the Management of Drug Resistant Tuberculosis in the UKNo drug interventionsNot AvailableNot Availablecompleted
NCT04166474
Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicintreatment4completed
NCT03819374
Improving HIV/Tuberculosis Outcomes in IrkutskNo drug interventionsNot AvailableNot Availablecompleted
NCT01098474
Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Healthy Infantsprevention2completed
NCT00788320
Vitamin D in Active Tuberculosis (TB) StudytreatmentNot Availablewithdrawn
NCT03154320
A Trial of Same-Day Testing and Treatment to Improve Outcomes Among Symptomatic Patients Newly Diagnosed With HIVNo drug interventionstreatmentNot Availablecompleted
NCT02156882
Establishment of a Clinical Trial Unit in Mavalane, Maputo, in MozambiqueNo drug interventionsNot AvailableNot Availablecompleted
NCT05202431
The Effect of Telephone Follow-up and Training on Treatment Adherence in Tuberculosis Patients and ContactsNo drug interventionssupportive_careNot Availablecompleted
NCT02978131
Histopathological Techniques and PCR on Tissues Included in Paraffin for the Diagnosis of TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03934931
Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial)No drug interventionspreventionNot Availableactive_not_recruiting
NCT04768231
Rifampicin at High Dose for Difficult-to-Treat Tuberculosistreatment2unknown_status
NCT00082173
Moxifloxacin As Part of a Multi-Drug Regimen For Tuberculosistreatment2completed
NCT01768273
Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolamtreatment1completed
NCT05282173
Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South AfricaNo drug interventionshealth_services_researchNot Availablecompleted
NCT04563273
Clinical Study of BCG Vaccine for Intradermal Injectionprevention1completed
NCT00546273
Clinical Trial to Study 4 Different Doses of the Vaccine RUTI in Healthy VolunteersNo drug interventionstreatment1completed
NCT00309673
Local Anesthesia and Tuberculin Skin Test in Infants and ChildrentreatmentNot Availableunknown_status
NCT02251327
Feasibility and Accuracy of a Novel Xpert CartridgeNo drug interventionsNot AvailableNot Availablecompleted
NCT00653627
A Study to Quantify Bacille Calmette Guerin (BCG) and Characterise the Immune Response After BCG VaccinationNo drug interventionsbasic_science1completed
NCT02534727
Sputum Pharmacokinetics of TB Drugs and Bacterial Drug ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT00346476
Characteristics and Prevalence of Tuberculosis and HIV in Masiphumelele Township, Cape Town, South AfricaNo drug interventionsNot AvailableNot Availablecompleted
NCT03544476
Mobile Health Intervention for Active TuberculosisNo drug interventionshealth_services_researchNot Availablecompleted
NCT04147676
Evaluation of Centralised TB Assay SolutionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01262976
Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive AdultsNo drug interventionsprevention2completed
NCT04899076
Stool Processing Kit (SPK) Evaluation for Pediatric Tuberculosis (TB)No drug interventionsNot AvailableNot Availablecompleted
NCT02795260
Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65(III-healthy)No drug interventionsdiagnostic3completed
NCT03141060
Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in HIV-Infected and HIV-Uninfected Children With MDR-TBtreatment1 / 2recruiting
NCT05175794
Triage Test for All Oral DR-TB Regimen (TRiAD Study)No drug interventionsNot AvailableNot Availablerecruiting
NCT05820594
Using BCG Vaccine to Understand Tuberculosis Infectionbasic_scienceNot Availablerecruiting
NCT03800394
Pharmacokinetics of Intracellular TFV-DP and FTC-TP in HIV-infected AdolescentsNo drug interventionsNot AvailableNot Availablecompleted
NCT02045394
Epidemiology and Diagnosis of Haemoptysis: a Multicenter StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03315962
Simplified Isoniazid Preventive Therapy Strategy to Reduce TB BurdenNo drug interventionspreventionNot Availablecompleted
NCT00203762
Effect of Public Sector Antiretroviral Treatment Programme on Tuberculosis and Immunization CareNo drug interventionstreatmentNot Availableunknown_status
NCT00108862
Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for TuberculosisNo drug interventionstreatment4completed
NCT01358162
Phase IC Study of Safety and PK of SQ109 300mg Dailytreatment1completed
NCT01194180
A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85Aprevention1completed
NCT05091580
Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South AfricaNo drug interventionstreatmentNot Availablerecruiting
NCT02231229
Rapid Detection of Rifampin and Isoniazid Resistance by PCR Before Tuberculosis (TB) Treatment InitiationNo drug interventionstreatment4completed
NCT02687529
Evaluation of the 4th Generation QuantiFERON-TB Test (QFT-Plus) for the Detection of Tuberculosis InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01436929
Effect of Prophylactic Use of Silymarin on Hepatotoxicity Induced by Anti-tuberculosis DrugspreventionNot Availableunknown_status
NCT04134689
DOT Selfie: A Mobile Technology Intervention to Evaluate Treatment Adherence Among Tuberculosis PatientsNo drug interventionshealth_services_researchNot Availablecompleted
NCT02135289
The Role of IGRA in Screening and Monitoring for TB During Anti TNF Therapy in Patients With IMIDNo drug interventionsNot AvailableNot Availablecompleted
NCT02533089
Training Lay Healthcare Workers to Optimize TB Care and Improve Outcomes in MalawiNo drug interventionshealth_services_researchNot Availablecompleted
NCT04221789
TB Treatment Support Tool Interactive Mobile App and Direct Adherence Monitoring on TB Treatment OutcomesNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02088892
A Clinical Challenge Study of BCG in Healthy VolunteersNot AvailableNot Availablecompleted
NCT04930744
Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)treatment2recruiting
NCT00440544
A Phase I Trial of a LTK63 Adjuvated Tuberculosis Nasal Subunit Vaccine (Ag85B-ESAT6)No drug interventionsprevention1terminated
NCT04179344
Usability Study of IeHS in IndonesiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00449644
TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB).treatment2completed
NCT05994144
"Conducting A Study On Video Observed Therapy In The Management Of Tuberculosis"No drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT02073240
Evaluation of an Enhanced Tuberculosis Infection Control Intervention in Healthcare Facilities in Vietnam and ThailandNo drug interventionsNot AvailableNot Availablecompleted
NCT01622140
Prospective Comparison of the Tuberculin Skin Test and Interferon-Gamma Release Assays in Diagnosing Infection With Mycobacterium Tuberculosis and in Predicting Progression to TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00004740
Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug UserspreventionNot Availableunknown_status
NCT02684240
A 14 Day Early Bactericidal Activity Study of Nitazoxanide for the Treatment of Tuberculosistreatment2completed
NCT02619240
Application of GeneXpert on Bronchoscopic Samples in the Clinical Management of Patients Suspicious of TBNo drug interventionsNot AvailableNot Availablecompleted
NCT02082340
Innovative Approach in Tuberculosis Care in ArmeniaNo drug interventionsotherNot Availablecompleted
NCT02911740
Additive Benefit of the Urine LAM Test to Current TB Diagnostics in HIV Positive Adults in Panama City, PanamaNo drug interventionsdiagnosticNot Availablewithdrawn
NCT02043067
Enhanced TB Screening to Determine the Prevalence and Incidence of TB in Patients With HIVNo drug interventionsNot AvailableNot Availablecompleted
NCT05283967
Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and AdultsNo drug interventionsNot AvailableNot Availablecompleted
NCT00707967
Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults.No drug interventionsprevention2completed
NCT05122767
Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS)other1 / 2recruiting
NCT04062201
Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Caretreatment3completed
NCT00341601
Multi-Drug Resistant Tuberculosis in KoreaNo drug interventionsNot AvailableNot Availablecompleted
NCT00405301
Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damagetreatment4completed
NCT06305104
Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.No drug interventionsdiagnostic2recruiting
NCT00330304
Isoniazid Prophylaxis With Concomitant Cotrimoxazole in HIV-infected Childrenprevention3completed
NCT04583904
Prospective Evaluation of Novel Diagnostics for Tuberculosis in KwaZulu-Natal, South AfricaNo drug interventionsNot AvailableNot Availablecompleted
NCT00197704
Nutrition, Immunology and Epidemiology of TuberculosisNo drug interventionsprevention3completed
NCT01687504
Pharmacokinetics of Anti-TB Drugs in HIV/TB Co-infected Children in GhanaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01244204
Role of Vitamin D in Innate Immunity to TuberculosisNo drug interventionspreventionNot Availablecompleted
NCT04242472
SMS-based Mobile Health Intervention for Nutritional Status and Treatment Outcome Among TB PatientsNo drug interventionsotherNot Availableunknown_status
NCT03026972
A Phase ⅠStudy of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-driedNo drug interventionsprevention1completed
NCT02176772
Iron Absorption and Utilization During Tuberculosis and After TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02861768
Improving the Diagnostic of TuberculosisNo drug interventionsdiagnosticNot Availablecompleted
NCT01530568
Gene Xpert Diagnosis of TB Using Tracheal Aspirates From Intensive Care Unit (ICU) PatientsNo drug interventionsdiagnosticNot Availablecompleted
NCT01121068
Monthly Follow up of Interferon Gamma Releasing Assay (IGRA) Among Health-care Workers Treating Tuberculosis (TB) PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05203068
Specificity Trial of the Recombinant Tuberculosis Allergen in BCG Vaccinated Healthy VolunteersNo drug interventionsdiagnosticNot Availablecompleted
NCT01977768
TB Immunotherapy Trial With Heat-killed M. Vaccaetreatment3completed
NCT06153069
Subclinical TB With Innovative Modified Short-course RegimensNo drug interventionstreatment4active_not_recruiting
NCT00992069
Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteerstreatment1completed
NCT00456469
Diagnosis of Active and Latent TB Infection With IFN-y Assays in African ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT04002869
Innovation in TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00982969
The Clinical Utility of QuantiFERON in the Diagnosis of Active TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00054769
Diagnosing Tuberculosis in HIV Infected Children in PeruNo drug interventionsNot AvailableNot Availablecompleted
NCT01497769
Safety of Tuberculosis Vaccine, MVA85A, Administered by the Aerosol Route and the Intradermal Routeprevention1completed
NCT02454569
Vicente Ferrer HIV Cohort StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06022146
TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contactsprevention3recruiting
NCT00810446
Safety And Efficacy Of Rifabutin In HIV PatientsNot AvailableNot Availablecompleted
NCT00728546
NAT2 in Re-challenge of INH in Patients With Hepatitistreatment4unknown_status
NCT03919812
Immunomodulatory Vitamin D in ThalassemiaNo drug interventionstreatmentNot Availablecompleted
NCT05382312
Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosisother2recruiting
NCT05581212
TB Case-Finding, Treatment and Prevention Intervention in ThailandNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT03080012
Salivary Therapeutic Drug Monitoring of Anti-Tuberculosis DrugsNo drug interventionsNot AvailableNot Availablecompleted
NCT01378312
A Study to Evaluate Safety and Immunogenicity of AERAS-402No drug interventionsprevention1completed
NCT04738812
Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune SuppressionNo drug interventionstreatment3recruiting
NCT00950612
Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative AdolescentsNo drug interventionsprevention2completed
NCT03075410
First Time in Human (FTIH) Safety and Pharmacokinetics (PK) Study of GSK3036656 in Healthy SubjectsNo drug interventionstreatment1completed
NCT00120510
Early Versus Standard Start of Anti-HIV Therapy for Treatment-Naive Adults in HaititreatmentNot Availablecompleted
NCT00402610
A Randomized Trial of Three Regimens to Prevent Tuberculosis in HIV-Infected Patients With Anergyprevention4completed
NCT06214910
ThiPhiSA: New Pathways to Prevention From Community TB Screening in South AfricaNo drug interventionshealth_services_researchNot Availablerecruiting
NCT05917210
Peer-led Implementation of TB-HIV Education and Adherence Counseling in UgandaNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT05044910
The Impact of Malnutrition on Immune Responses to TuberculosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01290081
Enhanced Tuberculosis Case Detection Among Substitution Treatment PatientsNo drug interventionshealth_services_researchNot Availablecompleted
NCT05738681
Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trialprevention2 / 3recruiting
NCT02288481
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult SubjectsNo drug interventionstreatment1completed
NCT05643781
Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT04230395
Alcohol Reduction Among People With TB and HIV in IndiaNo drug interventionstreatmentNot Availablerecruiting
NCT03497195
Achieving Tuberculosis (TB) Control In ZambiaNo drug interventionsdiagnosticNot Availablecompleted
NCT06485895
Clinical Evaluation of an IGRA Test for the Diagnosis of Active and Latent TuberculosisNo drug interventionsdiagnosticNot Availablerecruiting
NCT03228095
Volatiles in Breath and Headspace Analysis - Diagnostic MarkersNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05739695
A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary LesionsNo drug interventionsdiagnosticNot Availablerecruiting
NCT00052195
Investigational Vaccine for the Prevention of Disseminated Tuberculosis in HIV Infected PeopleNo drug interventionsprevention2 / 3completed
NCT02043314
A Bioequivalence Study of Two Different Dosages of Isoniazid Tablet Formulations in Human Healthy Volunteerstreatment1completed
NCT01874314
Effects of SQ109 on QTc Interval in Healthy Subjectstreatment1withdrawn
NCT03819114
Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapytreatment2completed
NCT01571414
Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampintreatment1completed
NCT00414414
A RCT of Prednisone as Adjunctive Therapy for Hospitalized Patients With Pulmonary TB and HIV Co-infectiontreatment3withdrawn
NCT02063555
Phase I Trial of DAR-901No drug interventionsprevention1completed
NCT02874755
Quality of Tuberculosis Care in Mumbai, IndiaNo drug interventionshealth_services_researchNot Availablecompleted
NCT05110950
Endobronchial Ultrasound Needle Aspiration With and Without SuctionNo drug interventionsdiagnosticNot Availableunknown_status
NCT00096850
Safety, Tolerability, and Blood Levels of Ritonavir-Boosted Atazanavir and Rifampin When Taken Together in HIV Uninfected AdultstreatmentNot Availablecompleted
NCT03423550
Development of a Rapid and Accurate Diagnostic Assay for TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01288950
Vitamin D Supplementation Enhances Immune Response to Bacille-Calmette-Guerin (BCG) Vaccination in InfantsNo drug interventionspreventionNot Availablecompleted
NCT04094350
Effect of Community Active Case Finding Strategies for Detection of Tuberculosis in CambodiaNo drug interventionsscreeningNot Availablecompleted
NCT00201123
Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungstreatment2completed
NCT01724723
Using Entecavir to Reduce Hepatitis in Highly Viremic HBV Patients During Anti-tuberculous Treatmentprevention4unknown_status
NCT02573623
Evaluation of an Innovative Tuberculosis Diagnostic TestNo drug interventionsNot AvailableNot Availableunknown_status
NCT02234908
Rewards for Tuberculosis Contact ScreeningNo drug interventionsdiagnosticNot Availablecompleted
NCT03211208
Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02380508
Heterologous Effects of BCG in Healthy UK AdultsNot AvailableNot Availablecompleted
NCT00214708
Can Screening People Registering With Primary Care Improve the Detection of Tuberculosis?No drug interventionsNot AvailableNot Availableunknown_status
NCT00756808
Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis (TB) in Elderly Residents of Nursing Homes?No drug interventionsNot AvailableNot Availablecompleted
NCT06224608
Phase I Clinical Trial to Evaluate the Safety of Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC) in Healthy Adults Aged 18-65 and Patients With Pulmonary TuberculosisNo drug interventionsdiagnostic1completed
NCT00000638
Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous InfectionpreventionNot Availablecompleted
NCT01574638
Evaluating the Pharmacokinetics of High-Dose Rifapentine When Given as a Single Dose or in Divided Doses to Healthy Adultstreatment1completed
NCT04547738
Influence of Filarial Infections on Tuberculosis Disease and Tuberculosis Vaccination in CameroonNo drug interventionsNot AvailableNot Availableunknown_status
NCT03639038
Tuberculosis Diagnosis by Flow CytometryNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05916638
MoMa Signature During GranulomatosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT01850043
The Epidemiology of TST Change in KoreaNo drug interventionsNot AvailableNot Availablecompleted
NCT01376843
Conversion Rate of (TST) Tuberculin Skin Test and Quantiferon-TB Gold In Tube Assay in Health Care WorkersNo drug interventionsNot AvailableNot Availablecompleted
NCT01986543
Interaction Between High Dose Rifampicine and Efavirenz in Pulmonary Tuberculosis and HIV Co-infectionNo drug interventionstreatment2unknown_status
NCT00617643
Nevirapine Drug Levels in HIV Positive Patients Also Receiving Rifampicin for Tuberculosistreatment4completed
NCT01516203
Phase 2a EBA Trial of AZD5847treatment2completed
NCT03266003
An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB TreatmentNo drug interventionshealth_services_researchNot Availablecompleted
NCT02075203
Evaluation of Safety, Immunogenicity, and Prevention of TB With AERAS-404 and BCG Revaccination in Healthy Adolescentsprevention2completed
NCT01690403
Interaction Study to Assess the Pharmacokinetic Interaction of Oral Administration of Rifapentine on ATRIPLA™ in HIV Patientsbasic_science1completed
NCT02735590
The Correlate of Risk Targeted Intervention Studyprevention2 / 3unknown_status
NCT00460590
Safety and Immunogenicity of MVA85A, in Healthy Volunteers in Cape Townprevention1completed
NCT01700790
Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With Rifampintreatment4terminated
NCT04043390
A One-stop Shop for the Same Day Diagnosis and Management of TB and HIVNo drug interventionsdiagnosticNot Availablecompleted
NCT04240990
Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute MalnutritionNo drug interventionsdiagnosticNot Availableunknown_status
NCT00979290
Adverse Reactions and Efficacy of Fixed-dose Combination Anti-tuberculosis (TB) DrugsNo drug interventionsNot AvailableNot Availablecompleted
NCT01872390
Start TB Patients on ART and Retain on Treatment (START Study)No drug interventionsotherNot Availablecompleted
NCT05947890
Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South AfricaNo drug interventionsprevention2recruiting
NCT00533390
Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mgtreatment4terminated
NCT03159364
Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic InfectionsNo drug interventionstreatment1 / 2unknown_status
NCT03927664
Clinico-radiological Classification of Peritoneal TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01616264
Reproducibility of Computed TomographyNo drug interventionsNot AvailableNot Availablecompleted
NCT04424264
The Effect of Rifampicin on the Pharmacokinetics of Intracellular Tenofovir-diphosphate and Tenofovir When Coadministered With Tenofovir Alafenamide Fumarate During the Maintenance Phase of Tuberculosis Treatment in TB/HIV-1 Coinfected Participantstreatment1completed
NCT05547464
Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated VolunteersNo drug interventionsprevention1 / 2active_not_recruiting
NCT06199921
ATORvastatin in Pulmonary TUBerculosistreatment2recruiting
NCT03338621
Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patientstreatment2 / 3completed
NCT00560521
Continuous Positive Airway Pressure on Tuberculosis Pleural EffusionNo drug interventionstreatmentNot Availablecompleted
NCT02744521
Training Inmate Peer Educators in Detecting Tuberculosis in a Developing Country Prison: A Cluster Randomized TrialNo drug interventionsdiagnosticNot Availableunknown_status
NCT00351702
Preventive Therapy for Tuberculosis in HIV Infected Personsprevention3completed
NCT03456102
Statin Adjunctive Therapy for TBtreatment2completed
NCT02413502
Leukapheresis Sampling for Immune Responses After BCG Vaccination in BCG-naïve Healthy Adults in the USbasic_science0completed
NCT00402402
Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in Patients With Chronic Liver DiseaseNo drug interventionsdiagnostic4completed
NCT01611402
Gene Expression in HIV and Tuberculosis Co-infectionNo drug interventionsNot AvailableNot Availablecompleted
NCT00146302
Should Low Birth Weight Infants Be Vaccinated With BCG Vaccine at Birth in Developing Countries?prevention4completed
NCT01365702
Tiotropium in Patients With Tuberculosis (TB) Destroyed LungNo drug interventionsNot AvailableNot Availableunknown_status
NCT01138202
Pharmacokinetics (PK) and Safety of 2 Different Doses of Lopinavir/Ritonavir in in HIV/Tuberculosis (TB) Co-infected Patients Receiving Rifampicin Containing Anti-tuberculosis TherapyNo drug interventionsother2completed
NCT04311502
Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Studytreatment2completed
NCT00396084
Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosistreatment1 / 2completed
NCT00145184
Effect of Multivitamin Supplements on Clinical and Immunological Response in Childhood TuberculosisNo drug interventionstreatment3terminated
NCT03794284
Multiplex PCR -Microarray-based Assay in the Detection of MycobacteriumNo drug interventionsNot AvailableNot Availablecompleted
NCT01547884
Effect of Filarial Infection on Immune Responses in Latent TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT02959684
Strategic Screening for Infectious Diseases (Tuberculosis, HIV, HBV, HCV) Amongst Migrants in FranceNo drug interventionsNot AvailableNot Availableunknown_status
NCT00005379
Tuberculosis in a Multiethnic Inner City PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT04513379
Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patientstreatment3unknown_status
NCT02497079
Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA SamplesNo drug interventionsdiagnosticNot Availableunknown_status
NCT00640887
Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africatreatment2completed
NCT02596087
Improving Quality by Maintaining Accurate Problems in the EHRNo drug interventionsotherNot Availablecompleted
NCT05656287
My Mobile Wallet: An Intervention for Tuberculosis Medication Adherence in Rural UgandaNo drug interventionssupportive_careNot Availablerecruiting
NCT00107887
TB (Tuberculosis) Preventive Therapy for HIV Patients With Access to HAART (Highly Active Antiretroviral Therapy)prevention4completed
NCT05136833
Evaluation of Efficacy and Safety of the Concomitant of RUTI® Immunotherapy With the Standard Treatment in TB Patientstreatment2withdrawn
NCT00216333
Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary TuberculosisNo drug interventionstreatment4unknown_status
NCT00173433
Exogenous Reinfection of Tuberculosis in TaiwanNo drug interventionsNot AvailableNot Availablecompleted
NCT01699633
Rifampin and Nevirapine Interactions in Young ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT04064554
Clinical Study to Evaluate Safety and Immunogenicity of Bacillus Calmette-Guerin (BCG) Delivery Via Novel Micronjet600 Device Compared to Those Via Conventional NeedleNo drug interventionspreventionNot Availablecompleted
NCT05628454
Comparison of Three Different Puncture Techniques in EBUS-TBNANo drug interventionsdiagnosticNot Availablerecruiting
NCT01690754
Evaluating the Effectiveness of Interactive SMS Reminders on TB Treatment OutcomesNo drug interventionssupportive_careNot Availablecompleted
NCT03042754
Improve Treatment Outcomes for Tuberculosis Infection in Tertiary Care HospitalsNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT06246851
BCG Revaccination Study in Diabetic and Non-Diabetic AdultsNo drug interventionsotherNot Availablerecruiting
NCT00495651
Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO)treatment3completed
NCT00476853
Efficacy Safety Study Comparing 2 Doses of NVP After Initiating Rifampin-containing TB Therapytreatment2completed
NCT00201253
Expression of Tuberculosis in the LungNo drug interventionsNot AvailableNot Availablecompleted
NCT04260477
Novel Triple-dose Tuberculosis Retreatment Regimentreatment3active_not_recruiting
NCT01587677
Evaluation of a LAM FLISA for the Diagnosis of TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT02348177
Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and TBtreatment4completed
NCT02500277
Yield of Cryoprobe vs Flexible Forceps Pleural BiopsyNo drug interventionsdiagnosticNot Availablecompleted
NCT01471977
Treatment Adherence of Tuberculosis MedicinesNo drug interventionspreventionNot Availablecompleted
NCT03882177
StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosistreatment2completed
NCT02245347
Genome Sequencing of Multidrug Resistant Tuberculosis (MDR TB) in SputumNo drug interventionsNot AvailableNot Availableunknown_status
NCT01167647
The Role of Routine Bacterial Culture Including Tuberculosis During Bronchoscopy: A Prospective StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00130247
Tuberculosis Treatment Shortening Trialtreatment3completed
NCT04746547
Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TBtreatment4recruiting
NCT05423847
Triage UltraSound in Tb Endemic RegionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02700347
Whole Blood Bactericidal Activity Against Mycobacterium Tuberculosis of Pyrazinamide Plus Allopurinol in Healthy Volunteerstreatment1completed
NCT01456845
Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced HepatotoxicityNo drug interventionsNot AvailableNot Availablecompleted
NCT04618198
Early Empiric Anti-Mycobacterium Tuberculosis Therapy for Sepsis in Sub-Saharan AfricaNo drug interventionstreatment3recruiting
NCT01053598
Evaluation Of The Performance Of The Nitrate Reductase And Resazurin Titre Assay For The Detection of Mycobacterium Tuberculosis Complex From Sputum In A High Tb and Hiv SettingNo drug interventionsNot AvailableNot Availablecompleted
NCT04567498
eNose-TB: Electronic Nose for Tuberculosis ScreeningNo drug interventionsscreeningNot Availableactive_not_recruiting
NCT00771498
An Evaluation of the Pharmacological Interaction of Lopinavir/r and RifampinNot Available4completed
NCT00212498
Tuberculosis Research Blood BankNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02375698
A Phase I Study of Safety & Immunogenicity of AERAS-456 in HIV-Neg. Adults Treated for Drug-susceptible Pulmonary TBNo drug interventionsprevention1completed
NCT01311505
Bioequivalence Study Comparing Rifampicin In A Fixed-Dose Combination (Rifampicin+Isoniazid, Myrin© 2) And The Reference Drug (Rifampicin, Rimactane®)treatment1completed
NCT04745897
Accessibility of the World Health Organization's eTB Catalogue of RecommendationsNo drug interventionshealth_services_researchNot Availablecompleted
NCT01048697
Effect of Weight and/or Obesity on Ethambutol Drug ConcentrationsNot Available4completed
NCT03808597
Digital Health Promotion in Iringa, TanzaniaNo drug interventionspreventionNot Availablecompleted
NCT04271397
Immunological Biomarkers in Tuberculosis ManagementNo drug interventionsdiagnosticNot Availablerecruiting
NCT01589497
Essentiality of INH in TB Therapytreatment2completed
NCT00645697
Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular NeovascularizationNo drug interventionsNot AvailableNot Availablecompleted
NCT04443283
The Effect of Latent Tuberculosis Infection on the Pregnancy Outcome of IVF-ETNo drug interventionsNot AvailableNot Availableunknown_status
NCT00018083
Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients With HIV-Related Tuberculosis Treated With a Rifabutin-Based RegimentreatmentNot Availableunknown_status
NCT00456183
Safety and Immunogenicity of MVA85A in Volunteers Latently Infected With TB.prevention1completed
NCT03691883
Design of an Integrative Algorithm for Staging TuberculosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04743583
Prevalence and Malignant Involvement of Calcified Intrathoracic Lymph Nodes in Patients Undergoing EndosonographyNo drug interventionsNot AvailableNot Availablecompleted
NCT00023361
TBTC Study 23: Treatment of HIV-Related Tuberculosis Using a Rifabutin-Based RegimentreatmentNot Availablecompleted
NCT05842161
South Africa Smoking Cessation and Engagement in HIV/TB Care CareNo drug interventionstreatmentNot Availablerecruiting
NCT04152161
Bacille Calmette Guerin (BCG) Revaccination of Healthy Adolescents for the Prevention of Mycobacterium Tuberculosis Sustained Infectionprevention2active_not_recruiting
NCT02066428
A Phase I Randomized Placebo-Controlled, Double-Blind Study to Evaluate Safety and Immunogenicity of AERAS-404 Administered as Different Amounts of Antigen and Adjuvant Combinations in HIV-Negative BCG-Vaccinated Adults Without Evidence of Tuberculosis Infectionprevention1completed
NCT01442428
Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trialtreatment2 / 3withdrawn
NCT04518228
Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and PostpartumNot AvailableNot Availablerecruiting
NCT02778828
Pharmacokinetic and Therapeutic Adaptation of Linezolid in the Treatment of Multi-Resistant TuberculosisotherNot Availablecompleted
NCT04203628
Evaluation of Four Stool Processing Methods Combined With Xpert MTB/RIF Ultra for Diagnosis of Intrathoracic Paediatric TB (TB-Speed - Stool Processing)No drug interventionsdiagnosticNot Availablecompleted
NCT01040611
Effectiveness of Music TherapyNo drug interventionssupportive_careNot Availableunknown_status
NCT04538911
Phase I Clinical Protocol for Pre-evaluation of the Safety of BCG-PPD in Tuberculosis Patientsdiagnostic1recruiting
NCT00962793
Diagnosis of Latent Tuberculosis(TB) Infection in Health Care Workers Using TST and Whole Blood Interferon-γ AssayNo drug interventionsNot AvailableNot Availablecompleted
NCT04466293
Choice Architecture Based TB Preventive Therapy PrescribingNo drug interventionshealth_services_researchNot Availablecompleted
NCT02774993
Doxycycline in Human Pulmonary Tuberculosistreatment2completed
NCT03202693
A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects.treatment1completed
NCT02715271
Study of TB Lesions Obtained in Therapeutical SurgeryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00731471
A Phase I Study of a New Tuberculosis (TB) Vaccine, MVA85A, in Healthy Volunteers With HIVprevention1completed
NCT00814671
Study of Daily Rifapentine for Pulmonary Tuberculosistreatment2completed
NCT02729571
Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adultsprevention1 / 2completed
NCT00910871
To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.treatment2completed
NCT05805878
KAP Regarding Tuberculosis Among Physicians in Assiut CityNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06438978
Tuberculosis Vaccine in Healthy Indian Adultsprevention1active_not_recruiting
NCT03255278
Evaluation of the Safety and Immunogenicity of the Recombinant Subunit Vaccine "GamTBvac" Against the Tuberculosis.No drug interventionsprevention1completed
NCT00000778
A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacintreatment1completed
NCT04677478
Impact of the Respiratory Isolation on the Quality of Life in Patients Hospitalized for Tuberculosis or COVID-19No drug interventionsNot AvailableNot Availableunknown_status
NCT02709278
Aerosol BCG Challenge Trial in Healthy UK AdultsNo drug interventionsother1completed
NCT04629378
Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTBtreatment2completed
NCT01241188
A Trial of the C-Tb Skin Test, When Given Intradermally to Adult Patients Recently Diagnosed With Active Tuberculosis (TB)diagnostic2completed
NCT01417988
Prevention of Early Mortality by Presumptive Tuberculosis (TB) TreatmentNo drug interventionstreatment4terminated
NCT04466488
Prevent TB: Choice Architecture for TPT DeliveryNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT04545788
Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant TuberculosistreatmentNot Availableunknown_status
NCT03800888
Real-time Tuberculosis Medication Adherence Intervention in Rural Southwestern UgandaNo drug interventionssupportive_careNot Availableunknown_status
NCT00311207
Development of Tuberculosis Diagnostic KitNo drug interventionsNot AvailableNot Availableunknown_status
NCT00810407
Safety And Efficacy Of Rifabutin In Patients For Non-HIV PatientsNot AvailableNot Availablecompleted
NCT00728507
Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosistreatment2terminated
NCT02906007
Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIVtreatment1 / 2active_not_recruiting
NCT02808507
Comparative Effectiveness/Implementation of TB Case Finding in Rural South AfricaNo drug interventionsdiagnosticNot Availablecompleted
NCT00412009
Investigation of a Novel Approach to Improve Treatment Success Rates for Tuberculosis Patients in SenegalNo drug interventionstreatment4completed
NCT03230409
Impact of Nursing Interventions on Adherence to Treatment With Anti-tuberculosis Drugs in Children and AdolescentsNo drug interventionstreatmentNot Availablecompleted
NCT02602509
Evaluating Celecoxib Activity in Mycobacterium Tuberculosis: A Whole Blood Bactericidal Activity Study in Healthy Volunteerstreatment1completed
NCT01934309
Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western KenyaNo drug interventionshealth_services_researchNot Availablecompleted
NCT02298309
Test and Treat TB: A Proof of Concept Trial in South AfricaNo drug interventionsotherNot Availablecompleted
NCT02627209
The Serum Angiotensin Converting Enzyme and Lysozyme Levels in Patients Non-infectious and Infectious UveitisNo drug interventionsdiagnosticNot Availableunknown_status
NCT00692809
Impact of HIV Infection on Latent Tuberculosis (TB) Among Patients With HIV-TB Co-infectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02781909
Potential Efficacy and Safety of Using Adjunctive Ibuprofen for XDR-TB Tuberculosistreatment2completed
NCT03044509
Diagnosis of Tuberculosis in Swiss ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT00115609
Efficacy of Tenofovir-Emtricitabine and Efavirenz in HIV Infected Patients With Tuberculosis (ANRS129)treatment3completed
NCT01657656
Vitamin D Supplementations as Adjunct to Anti-Tuberculosis Drugs in MongoliaNo drug interventionstreatmentNot Availablecompleted
NCT02623556
Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 AllergenNo drug interventionsdiagnostic3completed
NCT02375256
A Leukapheresis Study for Immune Responses in Healthy US Adults Who Receive BCG Vaccination Followed by Boosting With AERAS-402No drug interventionsprevention1completed
NCT03822156
Clinical Analysis of the Patients With Cavitary Pulmonary TB and Endobronchial TB in the PPM-UUH CohortNo drug interventionsNot AvailableNot Availablecompleted
NCT00192556
Food Incentives for TB Treatment Compliance in East Timor (FITTCET)No drug interventionstreatmentNot Availablecompleted
NCT00904956
Study of Latent Tuberculosis Infection (LTBI) by High Resolution ScannerNo drug interventionsNot AvailableNot Availableunknown_status
NCT00216385
A Controlled Trial of a 4-Month Quinolone-Containing Regimen for the Treatment of Pulmonary Tuberculosistreatment3unknown_status
NCT03896685
Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)treatment3active_not_recruiting
NCT04909385
TB PCR in BAL and EBUS-TBNANo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02415985
Pharmacokinetics and Safety of Rifabutin 150 mg Once Daily Versus Rifabutin 300 mg Thrice Weeklyother2completed
NCT01322685
Development and Application of Rapid Nucleic Acid Diagnostic Kits for Clinical SpecimensNo drug interventionsNot AvailableNot Availableunknown_status
NCT06338215
Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and MortalityNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT05329415
Tuberculosis Drug Levels and Continuous Glucose Monitoring in Diabetic PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05047315
Evaluating a New Stool Based qPCR for Diagnosis of Tuberculosis in Children and People Living With HIVNo drug interventionsNot AvailableNot Availablerecruiting
NCT06239337
Evaluation of Xpert MTB/RIF Ultra in Stools and Urine to Improve Tuberculosis Diagnosis in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT01252537
Immunosuppression in HIV-infected Patients With Tuberculosis in EthiopiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01585532
Alere Mycobacterium Tuberculosis Urine StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04600232
TB-LAM in the Diagnosis of TBNo drug interventionsdiagnosticNot Availableunknown_status
NCT02729532
Effect of Xpert MTB/RIF on Patient OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT05609552
Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PETNot AvailableNot Availablerecruiting
NCT01167452
Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrationstreatment4completed
NCT05941052
Assessing Diagnostics At Point-of-care for TuberculosisNo drug interventionsdiagnosticNot Availablerecruiting
NCT00507000
Pulmonary Tuberculosis and Vitamin Dtreatment3unknown_status
NCT04179500
A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Volunteerstreatment2active_not_recruiting
NCT06403800
Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern TanzaniaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01979900
Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosisprevention3completed
NCT00000959
Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous InfectiontreatmentNot Availablecompleted
NCT03851159
Nyaditum Resae® as a Co-adjuvant During Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut MicrobiotaNo drug interventionsotherNot Availablerecruiting
NCT02651259
Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Womentreatment1 / 2completed
NCT00889759
The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak InvestigationNo drug interventionsNot AvailableNot Availablecompleted
NCT00800670
Study of the Safety and Immunogenicity of an Adenovirus-based Tuberculosis VaccineNo drug interventionsprevention1terminated
NCT03537170
Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, IndiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01137370
The Impact of Vitamin D on Tuberculosis Among KoreansNo drug interventionsNot AvailableNot Availablecompleted
NCT02337270
Phase 1 Clinical Trial of the Safety and Immunogenicity of an Adenovirus-based TB Vaccine Administered by AerosolNo drug interventionsprevention1completed
NCT02680470
Virtual Observed Therapy for Patients With TuberculosisNo drug interventionshealth_services_researchNot Availablecompleted
NCT02336542
Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10No drug interventionsdiagnostic2completed
NCT05964842
Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in UgandaNo drug interventionsscreeningNot Availablerecruiting
NCT00134342
Tuberculosis (TB) Screening for the Diagnosis of Latent TB in Immunocompromised PopulationsNo drug interventionsNot AvailableNot Availablecompleted
NCT00972699
Mentor Mothers: A Sustainable Family Intervention in South African TownshipsNo drug interventionshealth_services_research2completed
NCT02641106
VDOT for Monitoring Adherence to LTBI TreatmentNo drug interventionsotherNot Availablecompleted
NCT00332306
Safety and Efficacy of Two Once Daily Anti Retroviral Treatment Regimens Along With Anti-tuberculosis Treatmenttreatment3unknown_status
NCT02060006
TB-IRIS NSAID Cox-2 Inhibitor Prevention Trialprevention3unknown_status
NCT03831906
Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia)No drug interventionsdiagnosticNot Availablecompleted
NCT02430506
A Study to Evaluate Safety and Immunogenicity of AERAS-402 Administered in HIV-negative, BCG-vaccinated, QFT (+) and (-) Adults Without Evidence of TBNo drug interventionsprevention1completed
NCT03302949
Treating Tuberculosis Wasting With a High-protein SupplementNo drug interventionstreatmentNot Availableterminated
NCT00760149
Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosistreatment2completed
NCT00871949
Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy AdultsNot Available1completed
NCT02383849
IMPAACT P1106: Pharmacokinetic Characteristics of Antiretrovirals and Tuberculosis Medicines in Low Birth Weight InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT00797836
Quantiferon for Detection of Latent Tuberculosis in Healthcare WorkersNo drug interventionsdiagnostic4completed
NCT00004736
Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosistreatment1completed
NCT00091936
Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited SettingstreatmentNot Availablecompleted
NCT02412436
PK Study of Rifampicin Interactions With DMPA and Efavirenz in TBtreatment2completed
NCT01245036
Efficacy of Antituberculous Therapy in Management of SarcoidosisNo drug interventionstreatmentNot Availablecompleted
NCT01017536
Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated AdultsNo drug interventionsprevention2completed
NCT02532036
MVA85A Aerosol vs Intramuscular Vaccination in Adults With Latent Mycobacterium Tuberculosis (M. tb) Infectionother1terminated
NCT04239313
A Phase Ib Study of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)prevention1completed
NCT02654613
Scaling up TB and HIV Treatment IntegrationNo drug interventionshealth_services_researchNot Availablecompleted
NCT00425113
Metronidazole for Pulmonary Tuberculosis (South Korea)treatment2completed
NCT03199313
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolidtreatment1completed
NCT04033718
Inpatient Package to Reduce HIV and AIDS-related Death in ZambiaNo drug interventionsdiagnosticNot Availablecompleted
NCT05575518
A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosistreatment3recruiting
NCT04232618
Point-of-care Triage Test for Active TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00080119
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIVprevention2 / 3terminated
NCT01380119
Tuberculosis (TB) Immunotherapy Phase 2 StudyNo drug interventionstreatment2completed
NCT01841541
The Impact of Involving Informal Health Providers for Tuberculosis Control in SudanNo drug interventionshealth_services_researchNot Availablecompleted
NCT06021041
A Retrospective Study on the Treatment Pattern and Clinical Prognosis of Severe Tuberculosis PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03092817
Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)treatment3completed
NCT00144417
TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatmenttreatment2completed
NCT00707317
T Cell Interferon-gamma Release Assay (TIGRA) in Immunocompromised IndividualsNo drug interventionsNot AvailableNot Availablecompleted
NCT00604617
Interferon-Gamma Release Assays in Tuberculosis (TB) - HIV Co-infected ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT01525134
Feasibility of a Lateral Flow Urine Lipoarabinomannan (LAM) Test for Diagnosis of TuberculosisNo drug interventionsdiagnosticNot Availableunknown_status
NCT00749034
Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison With BCG in Healthy Male Volunteersprevention1completed
NCT03334734
Phase 2a Study of PBTZ169treatment2terminated
NCT01955824
A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Undergoing Flexible Bronchoscopytreatment2 / 3completed
NCT01364324
Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized PatientsNot AvailableNot Availablecompleted
NCT00737724
Simultaneous Versus Sequential Antiretroviral Therapy (ARV) Therapy and Mycobacterium Tuberculosis (MTB) TreatmenttreatmentNot Availableterminated
NCT01693224
Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South AfricaNo drug interventionsdiagnosticNot Availableunknown_status
NCT06318416
Precision Rifampin Trial for Personalized DosingNo drug interventionsdiagnostic1 / 2not_yet_recruiting
NCT03492216
Drinkers' Intervention to Prevent Tuberculosis (DIPT Study)No drug interventionspreventionNot Availablecompleted
NCT00472316
Innovative Approaches to Tuberculosis ControlNo drug interventionsNot AvailableNot Availablecompleted
NCT02980016
Evaluation of the Effect of 3HP vs Periodic 3HP vs 6H in HIV-Positive Individualsprevention3completed
NCT00000796
A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.treatmentNot Availablecompleted
NCT00929396
A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis (TB) Subunit Vaccine in Purified Protein Derivative (PPD) Positive Volunteersprevention1completed
NCT00398996
A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected PatientsNo drug interventionstreatment3completed
NCT00411996
The Pharmacokinetics and Safety of IDV/r With NRTIs in HIV/TB Co-infected Patients Receiving Rifampicintreatment1 / 2completed
NCT01433796
Screening for Tuberculosis in HIV-infected Patients Eligible for Antiretroviral TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT04923958
Rapid Research in Diagnostics Development for TB NetworkNo drug interventionsdiagnosticNot Availablerecruiting
NCT04613258
Soy, Catfish, Anchovy, and Rice Supplementation Increases 25(OH)D Serum Levels in Tuberculosis Patients With ComplicationsNo drug interventionsdiagnosticNot Availablecompleted
NCT00474435
Pharmacokinetics of Emtricitabine/Tenofovir/Efavirenz in HIV-infected Patients With Tuberculosistreatment2unknown_status
NCT06221735
Evaluating the Accuracy of New Tests for TB Infection DiagnosisNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT06563635
Frequency of Tuberculosis in Psoriasis PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01992263
Vitamin D Supplementation and TBNo drug interventionsotherNot Availableunknown_status
NCT01954563
Study Evaluating Aerosol and Intradermal Administration of a Candidate Tuberculosis (TB) Vaccine, MVA85A, as a Way to Increase Immune Response and Avoid Anti-vector Immunityprevention1completed
NCT03036163
Phase 1 Study of PBTZ169basic_science1completed
NCT05220163
Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19No drug interventionsscreeningNot Availablerecruiting
NCT05042063
Acoustic Cough Monitoring for the Management of Patients With Known Respiratory DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00922363
Trial on the Safety of a New Liposomal Adjuvant System, CAF01, When Given With the Tuberculosis Subunit Vaccine Ag85B-ESAT-6 as Two Injections With Two Months Interval to Healthy Adult VolunteersNo drug interventionsprevention1completed
NCT05280886
Multi-site Cohort Study for the Development of Personalized Pharmacotherapy in Patients With Tuberculosis (TB)No drug interventionsNot AvailableNot Availablerecruiting
NCT03100786
Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitistreatment3completed
NCT03806686
Phase 2a Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Healthcare Workersprevention2unknown_status
NCT01162486
Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy Volunteerstreatment1completed
NCT02393586
Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteerstreatment1completed
NCT01924286
Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisoneprevention3completed
NCT02256839
Evaluation of the QuantiFERON-TB Test.No drug interventionsNot AvailableNot Availablecompleted
NCT01830439
Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009)treatment1completed
NCT03625739
Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With TuberculosisNot AvailableNot Availablerecruiting
NCT00005739
Behavioral Interventions for Control of TBNo drug interventionsNot AvailableNot Availablecompleted
NCT06580639
The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. TuberculosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT00423839
A Phase I Study of the Safety and Immunogenicity of MVA85A in Healthy Gambian Volunteersprevention1completed
NCT02389322
Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65No drug interventionsdiagnostic2completed
NCT01059422
Raltegravir + Lamivudine/Abacavir in HIV/Tuberculosis Co-Infected Patientstreatment4completed
NCT02807025
Nasal, Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT03519425
A Pragmatic Randomised Study to Optimise Screening, Prevention and Care for Tuberculosis in MalawiNo drug interventionshealth_services_researchNot Availableunknown_status
NCT03356925
Improving TB Diagnosis and Treatment Through Basic, Applied and Health Systems ResearchNo drug interventionsdiagnosticNot Availablecompleted
NCT04871230
Dried Blood Spot Test to Assess TB in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT00915330
Rapid On-site Cytopathologic Evaluation in the Diagnosis of Hilar/Mediastinal AdenopathyNo drug interventionsdiagnosticNot Availablecompleted
NCT00512330
Lipoarabinomannan (LAM) Enzyme-Linked Immunosorbent Assay (ELISA) in Diagnostics of Childhood Tuberculosis (TB)No drug interventionsNot AvailableNot Availableunknown_status
NCT00427830
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Previously Received BCGprevention1completed
NCT02178748
Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescentsprevention2completed
NCT00023348
TBTC Study 23A: Pharmacokinetics of Intermittent Isoniazid and Rifabutin in HIV-TBtreatment2 / 3completed
NCT01960257
Wirelessly Observed Therapy in Comparison to Directly Observed Therapy for the Treatment of TuberculosisNo drug interventionssupportive_care4completed
NCT04781257
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African CountriesNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00265226
Efficacy and Safety Study of Immunomodulator as an Adjunct Therapy in Pulmonary Tuberculosis (TB) Retreatment Patientstreatment3completed
NCT00023426
TBTC Study 25: Study of the Tolerability of Higher Doses of Rifapentine in the Treatment of Tuberculosistreatment2completed
NCT04121026
Validation of a Tuberculosis Treatment Decision Algorithm in HIV-infected ChildrenNo drug interventionsdiagnosticNot Availableunknown_status
NCT04369326
Community Initiated Preventive Therapy for TBNo drug interventionspreventionNot Availablecompleted
NCT00495326
Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO)treatment2 / 3completed
NCT00816426
Measurement of Anti-TB Drugs in Lung Tissue From Patients Having Surgery to Treat Tuberculosisother1completed
NCT01631266
Comparison of Diagnostic Performance of C-Tb to QuantiFERON®-TB, in Combination With a Safety Assessment of C-Tb vs Tuberculin PPD RT23 SSIdiagnostic3completed
NCT01198366
Study of AERAS-402 in Healthy InfantsNo drug interventionsprevention1 / 2completed
NCT06178666
A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawibasic_scienceNot Availablenot_yet_recruiting
NCT00651066
Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in Vietnamtreatment2completed
NCT00423566
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers.prevention1completed
NCT03135366
Self-verification and Support Via Mobile Phones Drastically Improves Tuberculosis Treatment Success in LMIC SettingsNo drug interventionstreatmentNot Availablecompleted
NCT06058065
Sensitivity and Specificity of Xpert MTB/RIF UltraNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00557765
Use of a Gamma-IFN Assay in Contact Tracing for Tuberculosis in a Low-Incidence, High Immigration AreaNo drug interventionsNot AvailableNot Availablecompleted
NCT05124665
Interrupting HIV and TB Stigma in the Household in UgandaNo drug interventionshealth_services_researchNot Availablecompleted
NCT01162265
Prognostic Value of Interferon Gamma Release Assays in Predicting Active Tuberculosis Among Individuals With, or at Risk of, Latent Tuberculosis InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT02273765
Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosistreatment3completed
NCT01363765
Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in BrazilNo drug interventionsdiagnostic4completed
NCT01990274
The Utility of Intensified Case Finding Combined With a Package of Novel TB Diagnostics Using a Mobile Clinic in AfricaNo drug interventionsdiagnosticNot Availablecompleted
NCT01340820
Study of AERAS 422 in Healthy AdultsNo drug interventionstreatment1completed
NCT00395720
The Safety and Immunogenicity of a TB Vaccine; MVA85A, in Healthy Volunteers Who Are Infected With HIVprevention1completed
NCT05473520
Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosistreatment3recruiting
NCT01459120
Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural LesothoNo drug interventionshealth_services_researchNot Availablecompleted
NCT04216420
Electronic Pillbox-enabled SAT Versus DOT for TB Medication Adherence and Treatment OutcomesNo drug interventionstreatmentNot Availablecompleted
NCT00311220
Use TST and QFT-RD1 Test to Monitor the Tuberculous Infection in Patients, Close Contact People and Health Care WorkersNo drug interventionsdiagnostic4unknown_status
NCT01895582
Performance of IGRAs for TB Infection Diagnosis in ElderlyNo drug interventionsNot AvailableNot Availableterminated
NCT04141982
Clinical Concordance Evaluation of T-SPOT®.TB Assay Performance (T-Cell SelectTM Study)No drug interventionsNot AvailableNot Availablecompleted
NCT05756582
Prevalence of Latent Tuberculosis Infection in Health-care Workers and StudentsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01049282
A Safety and Immunogenicity Trial With an Adjuvanted TB Subunit Vaccine (Ag85B-ESAT-6 + IC31)No drug interventionsprevention1completed
NCT03559582
Diagnostics and Pharmacotherapy for Severe Forms of TB (DMID 15-0100)No drug interventionsNot AvailableNot Availablecompleted
NCT06512831
Isoniazid Prophylaxis Based on Risk Factors of Tuberculosis in Living Kidney Transplantation RecipientspreventionNot Availablecompleted
NCT03923231
Pharmacokinetics of Atazanavir in Special PopulationsNot AvailableNot Availablecompleted
NCT04249531
Pharmacokinetic Evaluation and Local Tolerability of Dry Powder Amikacin Via the Cyclops™treatment1unknown_status
NCT01936831
High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)treatment2completed
NCT02216331
PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)treatment1completed
NCT01683773
Safety Study of Tuberculosis Vaccines AERAS-402 and MVA85Aprevention1completed
NCT04551573
A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjectsbasic_science4withdrawn
NCT03545373
Accuracy and Consequences of Using Trial-of-antibiotics for TB Diagnosis (ACT-TB Study)diagnostic3completed
NCT02520973
Screening for TB in Pregnancy. on HIV-Infected Pregnant WomenNo drug interventionsdiagnosticNot Availablecompleted
NCT03106727
Evaluating the Impact of a Community Health Worker Program in Neno, MalawiNo drug interventionshealth_services_researchNot Availablecompleted
NCT02563327
Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosistreatment3unknown_status
NCT00953927
A Study of MVA85A in Healthy Infantsprevention2completed
NCT01828827
Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjectstreatment1completed
NCT04825327
Predicting the Future: Incipient TuberculosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02968927
TB Host Directed Therapytreatment2unknown_status
NCT01223976
Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With PsoriasisNo drug interventionsdiagnostic4unknown_status
NCT04557176
TB Screening Improves Preventive Therapy UptakeNo drug interventionsscreeningNot Availableactive_not_recruiting
NCT02193776
A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis.treatment2completed
NCT00962676
Diagnostic Usefulness of Interferon Gamma Release Assay for Active Tuberculosis in Immunocompromised PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02508376
Safety, Tolerability, and Immunogenicity of the Vaccine Candidates ID93 + AP10-602 and ID93 + GLA-SE Administered Intramuscularly in Healthy Adult Subjectsprevention1completed
NCT00004276
Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV Infectionstreatment2completed
NCT02142894
Evaluation of the QuantiFERON-TB Test.No drug interventionsNot AvailableNot Availablecompleted
NCT00541294
Diagnosis of Tuberculosis Infection in HIV Co-infected ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT04121494
ChAdOx1 85A Aerosol Versus Intramuscular Vaccination in Healthy Adults (TB039)No drug interventionsprevention0completed
NCT05824091
Safety, Tolerability, Pharmacokinetics (PK), and Food Effect of MK-7762 in Healthy AdultsNo drug interventionstreatment1completed
NCT03305991
Tuberculosis Infection in Women of Reproductive Age and Their InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT05847491
Latent Tuberculosis in Healthcare Workers - the Reality of a Portuguese Tertiary HospitalNo drug interventionsNot AvailableNot Availablerecruiting
NCT05398562
Tolerability and Reactogenicity Trial of the Recombinant Tuberculosis Allergen in Healthy VolunteersNo drug interventionsdiagnostic1completed
NCT01464762
Early Access of TMC207 in Patients With Extensively Drug Resistant or Pre-XDR Pulmonary TuberculosisNot AvailableNot Availableapproved_for_marketing
NCT06338462
Cali Sin Tos Aim 2No drug interventionspreventionNot Availablerecruiting
NCT02946762
TasP in Correctional FacilitiesNo drug interventionshealth_services_researchNot Availablecompleted
NCT03175380
Biological Samples Obtained by Leukapheresis Induced by Two BCG Vaccinations in BCG-naïve Healthy Adults in the USNo drug interventionsbasic_science0completed
NCT04721080
Pulmonary Tuberculosis Sequelae in Patients With COPDNo drug interventionsNot AvailableNot Availableunknown_status
NCT02027480
Antiretroviral Therapy and Inflammatory and Coagulation Biomarkers: iMACS StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02174380
Effectiveness of Active Case Finding of Household Contacts in a Routine Tuberculosis (TB) Control ProgramNo drug interventionsscreeningNot Availableunknown_status
NCT04463680
Rifampin and the Contraceptive Implantbasic_science4completed
NCT00828529
TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteertreatment1completed
NCT01033929
A Safety and Dose Finding Trial of C-Tb, When Given to Adult Patients Recently Diagnosed With Active TuberculosisNo drug interventionsdiagnostic1completed
NCT01124929
Treatment Duration for Abdominal TuberculosisNo drug interventionstreatment3completed
NCT02662829
Preventing Childhood Tuberculosis in Lesotho (PREVENT Study)No drug interventionspreventionNot Availablecompleted
NCT01151189
Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485)prevention2completed
NCT06526689
Lung Innate Immunity and Microbiome After Tuberculosis ExposureNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05539989
Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africaprevention1 / 2withdrawn
NCT05376189
Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosistreatment2 / 3unknown_status
NCT02689089
Taima TB: 3HP Studyprevention4completed
NCT01650389
Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccinationprevention2completed
NCT01301144
Oral Urea Breath Testing for Diagnosis and Treatment Response in Pulmonary TuberculosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00548444
T-Cell Turnover Following Vaccination With MVA85Aprevention1completed
NCT01704144
Rifampin and Efavirenz Interactions in Older ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT02420444
A Study for Safety and Immunogenicity of BCG and AERAS-404 in HIV-Negative, TB-Negative, BCG-Naive Adultsprevention1completed
NCT01165840
Effect of Weight and/or Obesity on Dapsone Drug Concentrationstreatment4completed
NCT05139940
Validation of Artificial Intelligence Enabled TB Screening and Diagnosis in ZambiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01225640
PNU-100480 In Newly Diagnosed, Drug Sensitive Patients With Pulmonary TB; Early Bactericidal Activity; Whole Blood Assaytreatment2completed
NCT00005740
TB Contact Investigation: Behavioral InterventionNo drug interventionsNot AvailableNot Availablecompleted
NCT04600167
Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitusprevention3recruiting
NCT03032367
TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study)other0completed
NCT01663701
Simplified Severe Sepsis Protocol-2 (SSSP-2) in ZambiaNo drug interventionstreatmentNot Availablecompleted
NCT01315301
Optimal Time to Initiate Antiretroviral Therapy in HIV & TB Coinfected Adults Being Treated for TuberculosisNo drug interventionssupportive_careNot Availableunknown_status
NCT03891901
A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutintreatment2completed
NCT01424501
Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Adults With TB DiseaseNo drug interventionsprevention2terminated
NCT04303104
Xpert Active Case-finding Trial 3 (XACT-3)No drug interventionsscreeningNot Availableactive_not_recruiting
NCT04620772
Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS Tuberculosistreatment2 / 3not_yet_recruiting
NCT01479972
Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africaprevention2completed
NCT03734172
Rapid and Accurate Diagnosis of Paediatric TB (RaPaed-AIDA-TB)No drug interventionsNot AvailableNot Availablecompleted
NCT02410772
TBTC Study 31: Rifapentine-containing Tuberculosis Treatment Shortening Regimenstreatment3completed
NCT06409572
Study of GeneXpert Mycobacterium Tuberculosis/ Rifampicin (MTB/RIF) Versus the Routine Methods for Detection of Mycobacterium TuberculosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00805272
Medical and Economical Impact of IGRAs Diagnosis of Latent Tuberculosis in HIV-infected PatientsNo drug interventionsdiagnosticNot Availablecompleted
NCT01932268
A Pilot Study for Pharmacokinetic Parameter of Colchicine in Patient Taking Rifampinbasic_science2completed
NCT02536768
Evaluation of South Africa's National Adherence StrategyNo drug interventionsotherNot Availablecompleted
NCT01751568
Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TBtreatment1 / 2completed
NCT01663168
EARNEST Rifabutin Pharmacokinetics (PK) Substudytreatment2unknown_status
NCT03459768
Cohort Study on People Who Inject Drugs in SenegalNo drug interventionsNot AvailableNot Availableunknown_status
NCT00233168
Effectiveness of Public Health Model of Latent Tuberculosis Infection Control for High-Risk AdolescentsNo drug interventionstreatmentNot Availablecompleted
NCT00741169
TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing.treatment1completed
NCT06457269
Evaluating the Potential of Large Language Models for Respiratory Disease ConsultationsNo drug interventionsdiagnosticNot Availablecompleted
NCT02613169
Infant TB Infection Prevention Studyprevention2completed
NCT02744469
Benin Population Diversity of Tuberculosis and ImplicationsNo drug interventionsNot AvailableNot Availablecompleted
NCT01587469
Evaluation of Xpert MTB/RIF Assay for the Rapid Identification of TB and TB Rifampin Resistance in Pulmonary Tuberculosis SuspectsNo drug interventionsNot AvailableNot Availablecompleted
NCT04490746
Identifcation of Biomarkers for Active Pulmonary TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00780546
Spatial Epidemiology of Tuberculosis (TB) InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT01660646
Determining the Impact of Enhanced Case Finding on Tuberculosis Notification in The GambiaNo drug interventionsdiagnosticNot Availablecompleted
NCT03767946
Epidemiological Study In Tuberculosis-Endemic Urban Area in SenegalNo drug interventionsNot AvailableNot Availablecompleted
NCT05284812
A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)prevention2suspended
NCT03802812
Thin Bronchoscope and Virtual Bronchoscopic Navigation System for TuberculosisNo drug interventionsdiagnosticNot Availablecompleted
NCT01404312
Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)prevention3completed
NCT00376012
Short Course Intermittent Regimens for the Treatment of HIV-Associated Tuberculosistreatment3unknown_status
NCT03758612
A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adultstreatment1completed
NCT05845112
Start Taking Action For TB DiagnosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06396910
TB and Sarcoidosis GranulomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02508610
DNA Sequencing of MDR TB in Eastern SiberiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00978510
Study of Health Personnel and the Assistance to Patients With Tuberculosis in Hospital EnvironmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01014481
Appropriate Timing of HAART in Co-infected HIV/TB Patientstreatment4terminated
NCT03800381
Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) TabletNo drug interventionsNot AvailableNot Availablerecruiting
NCT00096681
Prevalence of HIV and Tuberculosis in Masiphumelele Township, Cape Town, South AfricaNo drug interventionsNot AvailableNot Availablecompleted
NCT01113281
Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison to BCG in Healthy Volunteers in South Africaprevention1completed
NCT03557281
An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary TuberculosisNo drug interventionstreatment2completed
NCT00164281
Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in Botswanaprevention4completed
NCT02933281
MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africaprevention1 / 2completed
NCT02097095
Substudy of Protocol TB-018 (NCT01755598): Collection and Storage of Biological Samples for Evaluation of Correlates of TB (C-041-972)No drug interventionsNot AvailableNot Availablecompleted
NCT04721795
Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis)treatment2 / 3completed
NCT01356095
A Knowledge Translation Intervention for TB/HIV Treatment Adherence, in Zomba District, MalawiNo drug interventionshealth_services_researchNot Availablecompleted
NCT06047795
Endurance Training in Patients With Post-TB Lung DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT03341195
Mobile Phone SMS Messages and Automated Calls in Improving Vaccine Coverage Among Children in PakistanNo drug interventionspreventionNot Availableunknown_status
NCT01492595
Screening of Children in Household Contact With Adult TB Patients in Mbarara Hospital, UgandaNo drug interventionsNot AvailableNot Availablecompleted
NCT04121195
Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral LoadNo drug interventionstreatment2 / 3completed
NCT01579214
Cell Phone Messaging to Improve Communication of Critical Laboratory Results to Patients in Rural UgandaNo drug interventionshealth_services_researchNot Availablecompleted
NCT03084614
CD8 Reactivity to Microorganisms in Blood and Breast MilkNo drug interventionsNot AvailableNot Availableterminated
NCT02606214
A Multiple Ascending Dose Study With a Dose Formulation Comparison Cohort to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult SubjectsNo drug interventionstreatment1terminated
NCT01408914
Trial of High-Dose Rifampin in Patients With TBtreatment2completed
NCT03787914
Effect of Community Mobile Outreach Approach Compared to Facility Based Directly Observed Treatment Short Course on Treatment Outcome Among Tuberculosis Patients in Jeddah: A Randomized Controlled TrialNo drug interventionshealth_services_researchNot Availablecompleted
NCT02121314
HRZE Fasted/Fed in Newly Diagnosed TBNo drug interventionstreatment2completed
NCT00000955
Two-Stage Tuberculin (PPD) Skin Testing in Individuals With Human Immunodeficiency Virus (HIV) InfectionscreeningNot Availablecompleted
NCT00164450
TBTC Study 26 PK: Rifapentine Pharmacokinetics in Children During Treatment of Latent TB InfectiontreatmentNot Availablecompleted
NCT00000950
Metabolism of Antituberculosis Drugs in HIV-Infected Persons With TuberculosistreatmentNot Availablecompleted
NCT05534750
Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB)treatment2recruiting
NCT01329250
Pharmacokinetics and Safety of Moxifloxacintreatment4terminated
NCT02355223
Finding and Treating Unsuspected and Resistant TB to Reduce Hospital TransmissionNo drug interventionshealth_services_researchNot Availableunknown_status
NCT01811823
Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adultsbasic_science4completed
NCT05592223
Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccinesprevention1completed
NCT03832023
Community-based Tuberculosis Tracing and Preventive TherapyNo drug interventionshealth_services_researchNot Availablecompleted
NCT02457208
PK Study of Anti-TB Drugstreatment1completed
NCT01222338
Safety and Efficacy of Oral Immunomodulator in Tuberculosis (TB) and TB/HIV Patientstreatment2completed
NCT00005738
Promoting Adherence to TB Regimens in Latino AdolescentsNo drug interventionsNot AvailableNot Availablecompleted
NCT01494038
Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Womenprevention4completed
NCT05537038
Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in Healthy VolunteersNo drug interventionsprevention1active_not_recruiting
NCT04325438
The Impact of Pharmacists' Interventions on the Quality of Life of HIV-TB Co-infection Outpatients in IndonesiaNo drug interventionshealth_services_researchNot Availablecompleted
NCT03947138
A Study of GC3107(BCG Vaccine) in Healthy Infantsprevention3completed
NCT00170638
Tuberculosis Immunity in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT02605538
Hepatitis B in Cystic Fibrosis and Latent Tuberculosis RespectivelypreventionNot Availablewithdrawn
NCT00620438
Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patientstreatment4unknown_status
NCT03458338
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan AfricaNo drug interventionsNot AvailableNot Availablecompleted
NCT00811343
Impact of New Immunological Diagnosis Tests of Latent Tuberculosis Before Anti TNF TherapyNo drug interventionsdiagnosticNot Availablecompleted
NCT06017843
Impact Evaluation of Use of MATCH AI Predictive Modelling for Identification of Hotspots for TB Active Case FindingNo drug interventionshealth_services_researchNot Availablerecruiting
NCT06352970
Effects of Tuberculosis Infection on Development and Function of the PlacentaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04545164
Computer Aided Screening for Tuberculosis in Low Resource EnvironmentsNo drug interventionsdiagnosticNot Availablecompleted
NCT04148053
Evaluation of Immune Cell Markers in Diagnosis of TuberculosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05945498
Evaluation of ТВ/Flu-05Е Vaccine for the Prevention of Tuberculosis Infection in BCG-vaccinated Volunteers Aged 18-50 YearsNo drug interventionsprevention1completed
NCT04966052
COPD Co-infection With Tuberculosis on Th17 Cell DifferentiationNo drug interventionsNot AvailableNot Availablecompleted
NCT04677842
European Pregnancy and Paediatric Infections Cohort Collaboration: Paediatric ProtocolNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05685641
Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico CityNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01434758
Evaluating Diagnostics for Paediatric Tuberculosis by Blood CultureNo drug interventionsNot AvailableNot Availablecompleted
NCT01689831
Dose Study of Tuberculin Purified Protein Derivative (JHP/Dose)diagnostic2unknown_status
NCT05766267
Short-course Regimens for the Treatment of Pulmonary Tuberculosistreatment2 / 3recruiting
NCT01798095
Equivalence Study of Specificity of PPDdiagnostic2unknown_status
NCT06539455
Analysis of Liver Injury Risk Factors in a Multiethnic Population Treated With Antituberculosis DrugsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04988984
Development of Automated Molecular Diagnostic Platform for Tuberculosis Diagnosis (New Assay TB)No drug interventionsNot AvailableNot Availableunknown_status
NCT05413551
Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Preventiontreatment1recruiting
NCT03265977
A Phase II Study of H56:IC31 in Healthy AdolescentsNo drug interventionsprevention2withdrawn
NCT04453293
Immunization With BCG Vaccine to Prevent Tuberculosis Infectionprevention3recruiting
NCT05443178
Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapytreatment1recruiting
NCT05069688
Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicintreatment1recruiting
NCT02175849
Intensifying Multi-Drug Resistant Tuberculosis Contact Tracing by Social Network AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT04575519
Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosistreatment2recruiting
NCT04494516
Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT05122026
Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIVprevention1 / 2recruiting
NCT04236765
Tuberculosis In Children Visiting Friends and RelativesNo drug interventionsscreeningNot Availableunknown_status
NCT06289660
Multicenter Italian Cohort Study on Tuberculosis in Pediatric AgeNo drug interventionsNot AvailableNot Availablerecruiting
NCT05268380
Collision of Three Global Pandemics: the Effect of Tuberculosis and HIV on the Epidemiological, Clinical, Virological and Immunological Trajectory of COVID-19 in Botswana and NamibiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT06191692
1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnamtreatment3not_yet_recruiting
NCT03941210
Micro RNA as Prediction and/or Prognostic Markers of IRIS in TB-HIV Co-infected PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00480454
Safety, Immunogenicity, and Impact of MVA85A, on the Immunogenicity of the EPI Vaccinesprevention1completed
NCT01055145
Comparison of the Effect Between Levofloxacin and Moxifloxacin Among MDR-TB Patientstreatment3terminated
NCT04298905
Leveraging mHealth to Enable and Adapt CHW Strategies to Improve TB/HIV Patient Outcomes in SANo drug interventionsotherNot Availableactive_not_recruiting
NCT04645836
Impact of a Pharmacist-led Patient-centred Care Intervention Along With Text-Message Reminders, on the Management of Newly Diagnosed Tubercular Patients: a Protocol for a Randomized Controlled Trial'.No drug interventionshealth_services_researchNot Availablecompleted
NCT00480558
A Study of MVA85A, in Asymptomatic Volunteers Infected With TB, HIV or Bothprevention1completed
NCT00480714
A Study of the Immunogenicity of BCG, Delivered Intradermally in Healthy VolunteerspreventionNot Availablecompleted
NCT00424684
Comparison of the Quantiferon®-TB GOLD (in Tube) Assay With Tuberculin Skin Testing for Detecting Latent Tuberculosis Infection in Patients With Chronic Liver Disease Being Evaluated for or Awaiting Liver TransplantationNo drug interventionsdiagnosticNot Availablewithdrawn
NCT00480688
A Study of the Immunogenicity of M. Bovis BCG, Delivered Intradermally in Healthy VolunteersNo drug interventionsprevention1completed
NCT00654316
Study of the Safety and Immunogenicity of Bacille Calmette Guerin (BCG) Vaccineprevention1completed
NCT05405296
Evaluation of the Truenat™MTB Plus/COVID-19 Test for TB (Tuberculosis) and COVID-19 (SARS-CoV2)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03208725
Childhood Acute Illness and Nutrition NetworkNo drug interventionsNot AvailableNot Availableunknown_status
NCT04673227
Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI)No drug interventionsNot AvailableNot Availableunknown_status