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Displaying results 1221 - 1230 of 10000 in total
  1. Target

    Ephrin type-A receptor 2

    go.drugbank.com/bio_entities/BE0000841
    TargetHumans

    With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis … May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.

    Polypeptides: Ephrin type-A receptor 2
  2. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0001557
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase A
  3. Target

    Inositol-trisphosphate 3-kinase A

    go.drugbank.com/bio_entities/BE0001627
    TargetHumans

    Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis

    Polypeptides: Inositol-trisphosphate 3-kinase ASynonyms: IP3K A, IP3 3-kinase A
  4. Target

    Complement C1q subcomponent subunit A

    go.drugbank.com/bio_entities/BE0002094
    TargetHumans

    The C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM (PubMed:19706439, PubMed:24626930, PubMed:29449492). … Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens

    Polypeptides: Complement C1q subcomponent subunit A
  5. Target

    Amine oxidase [flavin-containing] A

    go.drugbank.com/bio_entities/BE0002198
    TargetEnzymeHumans

    of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:18391214, PubMed:20493079, PubMed:24169519, PubMed:8316221). … Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism

    Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type A
  6. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0002739
    TargetClostridium stercorarium

    Endoxylanase that degrades arabinoxylan and glucuronoxylan to xylobiose and xylotriose (in vitro).

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: 1,4-beta-D-xylan xylanohydrolase A
  7. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0003244
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: Xylanase A, 1,4-beta-D-xylan xylanohydrolase A
  8. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0008383
    TargetStaphylococcus aureus

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  9. Target

    Ephrin type-A receptor 1

    go.drugbank.com/bio_entities/BE0009436
    TargetHumans

    Also plays a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis … Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand.

    Polypeptides: Ephrin type-A receptor 1
  10. Target

    Ephrin type-A receptor 8

    go.drugbank.com/bio_entities/BE0009440
    TargetHumans

    During development of the nervous system also plays a role in axon guidance. … The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation.

    Polypeptides: Ephrin type-A receptor 8