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Triggering receptor expressed on myeloid cells 2
go.drugbank.com/bio_entities/BE0020451TargetHumansIn dendritic cells, receptor of SEMA6D with PLEXNA1 as coreceptor and mediates up-regulation of chemokine receptor CCR7 and dendritic cell maturation and survival (PubMed:11602640). … Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849).
Polypeptides: Triggering receptor expressed on myeloid cells 2Synonyms: Triggering receptor expressed on monocytes 2T cell receptor beta variable 5-6
go.drugbank.com/bio_entities/BE0023691TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).
Polypeptides: T cell receptor beta variable 5-6Nisevokitug
go.drugbank.com/drugs/DB17561InvestigationalNisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety
Diatrizoate
go.drugbank.com/drugs/DB00271ApprovedVet approvedA commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Mixtures: MD- GASTROVIEW® (MEDIO DE CONTRASTE PARA RADIOGRAFIA), MD- GASTROVIEW® (MEDIO DE CONTRASTE PARA RADIOGRAFIA)Simenepag isopropyl
go.drugbank.com/drugs/DB12977InvestigationalSimenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Gamma-aminobutyric acid receptor subunit alpha-2
go.drugbank.com/bio_entities/BE0000381TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:29961870, PubMed:31032849). GABA-gated chloride channe...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABA(A) receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-5
go.drugbank.com/bio_entities/BE0000471TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:14993607, PubMed:29961870, PubMed:30140029, PubMed:31056671). GABA-gate...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABA(A) receptor subunit alpha-5Gamma-aminobutyric acid receptor subunit alpha-3
go.drugbank.com/bio_entities/BE0000523TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:16412217, PubMed:29053855). GABA-gated chloride channels, also named GA...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-3Synonyms: GABA(A) receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-1
go.drugbank.com/bio_entities/BE0000795TargetHumansGABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response (By similarity).
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1Synonyms: GABA(A) receptor subunit alpha-1Tumor necrosis factor receptor superfamily member 1B
go.drugbank.com/bio_entities/BE0000949TargetHumansReceptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. … This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity
Polypeptides: Tumor necrosis factor receptor superfamily member 1BSynonyms: p80 TNF-alpha receptor, Tumor necrosis factor receptor 2