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Rezafungin
go.drugbank.com/drugs/DB16310ApprovedInvestigationalIt can only be administered intravenously but does not reach therapeutic concentrations in the central nervous system, eye and urine. … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)-Vildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational[L32813] Vildagliptin is currently under investigation in the US. … It is marketed as Galvus.[L32803] Vildagliptin is also available as Eucreas, a fixed-dose formulation with metformin for adults in who do not adequately glycemic control from monotherapy.
Mixtures: GALVUS® MET 50/500 COMPRIMIDOS RECUBIERTOS CON PELICULA, GALVUS® MET COMPRIMIDO RECUBIERTO CON PELICULA 50 MG/850 MGCategories: DPP-IV Inhibitors, Drugs Used in DiabetesAspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Mixtures: Vamin N, OLIMEL N5-860 E INFÜZYON IÇIN ELEKTROLITLI AMINOASIT ÇÖZELTISI, GLUKOZ ÇÖZELTISI VE LIPID EMÜLSIYONU, 1500 MLSynonyms: (S)-2-aminosuccinic acid, (S)-2-aminobutanedioic acidIpecac
go.drugbank.com/drugs/DB13293ApprovedWithdrawn[L2753] Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. … [L1113] The FDA does not have currently any approved product containing ipecac, however, ipecac as an ingredient is accepted to be sold over the counter in packages of 1 fluid ounce (30 ml) for the emergency
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNeon
go.drugbank.com/drugs/DB11589ApprovedIt is the fifth most abundant chemical element in the universe by mass but a rare element on Earth. … Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic.
Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 MixtureSynonyms: NeZoledronic acid
go.drugbank.com/drugs/DB00399ApprovedInvestigational[L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994.[A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712] … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid].
Salts: Zoledronate D,L-Lysine MonohydrateCategories: Heterocyclic Compounds, 1-RingHead Injury
go.drugbank.com/conditions/DBCOND0028168Drugs: CerebrolysinSynonyms: (Minor head injury) or (intracranial injury NOS without mention of open intracranial wound, with no loss of consciousness)Zotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawn[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.[A31857] Zotepine was never approved by the FDA. … In 1993, it was classified as inactive drug substance (Status I, Type II) and in 1995 the FDA studied the manufacturing procedures of Zotepine tablets in Germany, but the status remained inactive.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: ZOLEPTIL © 50 MG TABLETAS RECUBIERTAS.Rho-associated protein kinase 1
go.drugbank.com/bio_entities/BE0001016TargetHumansProtein kinase which is a key regulator of the actin cytoskeleton and cell polarity (PubMed:10436159, PubMed:10652353, PubMed:11018042, PubMed:11283607, PubMed:17158456, PubMed:18573880, PubMed:19131646, PubMed:8617235, PubMed:9722579). ...
Synonyms: ROCK-I, Rho-associated, coiled-coil-containing protein kinase I