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Displaying results 1271 - 1280 of 10000 in total
  1. Drug

    Osimertinib

    go.drugbank.com/drugs/DB09330
    ApprovedInvestigational

    Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals. Its use is indicated for the treatment of metastatic non-small cell lung canc...

    Products: TAGRISSO® 40 MG, TAGRISSO® 80 MG.
  2. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    In 2009, vinflunine was approved by the European Medicines Agency (EMA) as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment [A32626]. … Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396].

    Synonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastineProducts: Javlor Concentrate for Solution for Infusion 25 mg/mL
  3. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment...

    Mixtures: Implicor 50 mg /7,5 mg Filmtabletten, Implicor 50 mg/5 mg FilmtablettenProducts: IVABRADINA DOC GENERICI, CORALAN 5 MG
  4. Drug

    Zofenopril

    go.drugbank.com/drugs/DB13166
    ApprovedInvestigational

    Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.

    Mixtures: Zofenil plus 30 mg/12,5 mg Filmtabletten, ZOPROTEC PLUS 30 MG/12.5 MG FILM KAPLI TABLET, 28 ADETProducts: BIFRIL TABLET 30 mg, Zofenil 15 mg Filmtabletten
  5. Drug

    Cyclobenzaprine

    go.drugbank.com/drugs/DB00924
    ApprovedInvestigational

    Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepre...

    Mixtures: Cyclo/Gaba 10/300 Pack, Cyclo/MagProducts: MITRUL® 15 MG, TONALGEN® COMPRIMIDOS 5 MG
  6. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for addition...

    Categories: Immunoglobulin GSynonyms: ABP 206
  7. Drug

    Factor XIII (human)

    go.drugbank.com/drugs/DB12909
    ApprovedInvestigational

    Compared to Factor XIII (human), which is purified from pooled human plasma, [DB09310] is produced through recombinant DNA technology where the target protein is grown in yeast and then isolated [FDA Label

    Products: Corifact 250, Fibrogammin 250 IE Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung
  8. Drug

    Valethamate

    go.drugbank.com/drugs/DB13497
    Investigational

    Mixtures: EPIDOSIN COMPOSITUM 10 MG AMPUL, 3 ADETProducts: EPIDOSIN 20 MG SUPPOZITUAR, 6 ADET, EPIDOSIN 8 MG/8 ML AMPUL, 5 ADET
  9. Drug

    Diosmin

    go.drugbank.com/drugs/DB08995
    ApprovedInvestigational

    Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bio...

    Mixtures: DAFLON TABLET 500 mg, VENOMAX ® 500 MG TABLETASProducts: VENDIOS 600 MG TABLET, 30 ADET, Diosmin STADA 500 mg Filmtabletten
  10. Drug

    Guanfacine

    go.drugbank.com/drugs/DB01018
    ApprovedInvestigational

    Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release

    Products: GUAGO 1 MG UZATILMIŞ SALIMLI TABLET, 7 ADET, GUAGO 2 MG UZATILMIŞ SALIMLI TABLET, 7 ADET