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A disintegrin and metalloproteinase with thrombospondin motifs 13
go.drugbank.com/bio_entities/BE0009336EnzymeTargetHumansCleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 13C-type lectin domain family 12 member A
go.drugbank.com/bio_entities/BE0010945TargetHumansActs as a pattern-recognition receptor for NETs in neutrophils: specifically recognizes DNA in NETs, leading to inhibit neutrophil activation and limit further NET formation (PubMed:39143217). … Also acts as an inhibitor of dendritic cell maturation in an IL10-dependent manner (PubMed:16239426)
Polypeptides: C-type lectin domain family 12 member APhenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalPhenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. … Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization.
Mixtures: Kank-A with Blistex Medicated Lip, Phenol Saline InjCategories: Compounds used in a research, industrial, or household setting2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
go.drugbank.com/bio_entities/BE0000518TargetHumansPyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA
Polypeptides: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialA disintegrin and metalloproteinase with thrombospondin motifs 5
go.drugbank.com/bio_entities/BE0003730TargetHumansPlays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its VCAN remodeling properties. … Participates in development of brown adipose tissue and browning of white adipose tissue (By similarity).
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 5Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 11Garcinia gummi-gutta fruit
go.drugbank.com/drugs/DB14365InvestigationalGarcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Ari S-LinerProducts: Ari S-LinerPotassium voltage-gated channel subfamily A member 1
go.drugbank.com/bio_entities/BE0000781TargetHumansRegulates the frequency of neuronal action potential firing in response to mechanical stimuli, and plays a role in the perception of pain caused by mechanical stimuli, but does not play a role in the perception … In contrast, a heterotetrameric channel formed by KCNA1 and KCNA4 shows rapid inactivation (PubMed:17156368).
Polypeptides: Potassium voltage-gated channel subfamily A member 1HLA class I histocompatibility antigen, A alpha chain
go.drugbank.com/bio_entities/BE0003483TargetHumansIn complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived peptides on antigen-presenting cells for recognition by alpha-beta T cell receptor (TCR) on HLA-A-restricted CD8-positive
Polypeptides: HLA class I histocompatibility antigen, A alpha chainSynonyms: HLA-A, MHC class I antigen A*3Potassium voltage-gated channel subfamily A member 7
go.drugbank.com/bio_entities/BE0004719TargetHumansAssuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with
Polypeptides: Potassium voltage-gated channel subfamily A member 7C-type lectin domain family 14 member A
go.drugbank.com/bio_entities/BE0005467TargetHumansPolypeptides: C-type lectin domain family 14 member A