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Transient receptor potential cation channel subfamily V member 3
go.drugbank.com/bio_entities/BE0003416TargetHumansNon-selective calcium permeant cation channel (PubMed:12077604, PubMed:12077606, PubMed:26818531, PubMed:37648856, PubMed:38691614). It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures...
Polypeptides: Transient receptor potential cation channel subfamily V member 3Synonyms: Vanilloid receptor-like 3Transient receptor potential cation channel subfamily M member 7
go.drugbank.com/bio_entities/BE0004624TargetTransporterHumansBifunctional protein that combines an ion channel with an intrinsic kinase domain, enabling it to modulate cellular functions either by conducting ions through the pore or by phosphorylating downstream proteins via its kinase domain. The...
Polypeptides: Transient receptor potential cation channel subfamily M member 7Synonyms: Long transient receptor potential channel 7Transient receptor potential cation channel subfamily V member 5
go.drugbank.com/bio_entities/BE0005112TransporterHumansConstitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubu...
Polypeptides: Transient receptor potential cation channel subfamily V member 5Transient receptor potential cation channel subfamily M member 6
go.drugbank.com/bio_entities/BE0005126TransporterHumansBifunctional protein that combines an ion channel with an intrinsic kinase domain, enabling it to modulate cellular functions either by conducting ions through the pore or by phosphorylating downstream proteins via its kinase domain (Pub...
Polypeptides: Transient receptor potential cation channel subfamily M member 6Transient receptor potential cation channel subfamily V member 4
go.drugbank.com/bio_entities/BE0009159TargetHumansNon-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity (PubMed:16293632, PubMed:18695040, PubMed:18826956, PubMed:22526352, PubMed:23136043, PubMed:29899501). Activation by exposure to hypoto...
Polypeptides: Transient receptor potential cation channel subfamily V member 4Synonyms: Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2B-cell antigen receptor complex-associated protein beta chain
go.drugbank.com/bio_entities/BE0009680TargetHumansRequired in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to
Polypeptides: B-cell antigen receptor complex-associated protein beta chainTransient receptor potential cation channel subfamily M member 4
go.drugbank.com/bio_entities/BE0009748TargetHumansCalcium-activated selective cation channel that mediates membrane depolarization (PubMed:12015988, PubMed:12842017, PubMed:29211723, PubMed:30528822). While it is activated by increase in intracellular Ca(2+), it is impermeable to it (Pu...
Polypeptides: Transient receptor potential cation channel subfamily M member 4Synonyms: Long transient receptor potential channel 4Miricorilant
go.drugbank.com/drugs/DB16234InvestigationalMiricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesPipradrol
go.drugbank.com/drugs/DB11584ApprovedWithdrawnIt is currently classified under the Misuse of Drugs Act as a Class C substance [L2522]. … Interestingly, this drug has been studied for bactericidal properties, however, is not currently, used for this purpose [A32725].
Categories: Heterocyclic Compounds, 1-RingAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death. … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.
Mixtures: NEUPAX DUO-SCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring