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Displaying results 1291 - 1300 of 10000 in total
  1. Target

    Transient receptor potential cation channel subfamily V member 5

    go.drugbank.com/bio_entities/BE0005112
    TransporterHumans

    Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubu...

    Polypeptides: Transient receptor potential cation channel subfamily V member 5
  2. Target

    Transient receptor potential cation channel subfamily M member 6

    go.drugbank.com/bio_entities/BE0005126
    TransporterHumans

    Bifunctional protein that combines an ion channel with an intrinsic kinase domain, enabling it to modulate cellular functions either by conducting ions through the pore or by phosphorylating downstream proteins via its kinase domain (Pub...

    Polypeptides: Transient receptor potential cation channel subfamily M member 6
  3. Target

    Transient receptor potential cation channel subfamily V member 4

    go.drugbank.com/bio_entities/BE0009159
    TargetHumans

    Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity (PubMed:16293632, PubMed:18695040, PubMed:18826956, PubMed:22526352, PubMed:23136043, PubMed:29899501). Activation by exposure to hypoto...

    Polypeptides: Transient receptor potential cation channel subfamily V member 4Synonyms: Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2
  4. Target

    B-cell antigen receptor complex-associated protein beta chain

    go.drugbank.com/bio_entities/BE0009680
    TargetHumans

    Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to

    Polypeptides: B-cell antigen receptor complex-associated protein beta chain
  5. Target

    Transient receptor potential cation channel subfamily M member 4

    go.drugbank.com/bio_entities/BE0009748
    TargetHumans

    Calcium-activated selective cation channel that mediates membrane depolarization (PubMed:12015988, PubMed:12842017, PubMed:29211723, PubMed:30528822). While it is activated by increase in intracellular Ca(2+), it is impermeable to it (Pu...

    Polypeptides: Transient receptor potential cation channel subfamily M member 4Synonyms: Long transient receptor potential channel 4
  6. Drug

    VM4-037

    go.drugbank.com/drugs/DB15319
    Investigational

    VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).

  7. Drug

    SGX-001

    go.drugbank.com/drugs/DB33968
    Experimental

    SGX-001 is under investigation in clinical trial NCT07826767 (Open-label Gene Therapy Study in p47-CGD).

  8. Drug

    Glutamic acid

    go.drugbank.com/drugs/DB00142
    ApprovedInvestigationalNutraceutical

    A peptide that is a homopolymer of glutamic acid.

    Mixtures: Olimel 7.6% E, Olimel 4.4% E
  9. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Later they continued to be investigated for use in heart failure throughout the 1970-1980s. … Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize.

    Mixtures: NIF TEN 50, NIF-TEN CAPSULECategories: Adrenergic beta-1 Receptor Antagonists
  10. Drug

    Threonine

    go.drugbank.com/drugs/DB00156
    ApprovedInvestigationalNutraceutical

    An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.

    Mixtures: Clinimix E, Clinimix E