Search
Proto-oncogene tyrosine-protein kinase receptor Ret
go.drugbank.com/bio_entities/BE0002411TargetHumansAlso active in the absence of ligand, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage (PubMed:21357690). … Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation in response to glia cell line-derived
Polypeptides: Proto-oncogene tyrosine-protein kinase receptor RetTumor necrosis factor receptor superfamily member 8
go.drugbank.com/bio_entities/BE0003479TargetHumansReceptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts.
Polypeptides: Tumor necrosis factor receptor superfamily member 8Synonyms: CD30L receptorParathyroid hormone/parathyroid hormone-related peptide receptor
go.drugbank.com/bio_entities/BE0003508TargetHumansG protein-coupled receptor for parathyroid hormone (PTH) and for parathyroid hormone-related peptide (PTHLH) (PubMed:10913300, PubMed:11773434, PubMed:18375760, PubMed:19674967, PubMed:27160269, PubMed
Polypeptides: Parathyroid hormone/parathyroid hormone-related peptide receptorSynonyms: PTH1 receptor, PTH/PTHr receptorGamma-aminobutyric acid receptor subunit gamma-1
go.drugbank.com/bio_entities/BE0003593TargetHumansGamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790). GABA-gated chloride channels, also named GABA(A) receptors (...
Polypeptides: Gamma-aminobutyric acid receptor subunit gamma-1Synonyms: GABA(A) receptor subunit gamma-1Gamma-aminobutyric acid receptor subunit rho-3
go.drugbank.com/bio_entities/BE0003619TargetHumansRho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (By similarity). Rho-containing GABA-gated chloride ...
Polypeptides: Gamma-aminobutyric acid receptor subunit rho-3Synonyms: GABA(C) receptor, GABA(A) receptor subunit rho-3Acetylcholine receptor subunit alpha-type unc-63
go.drugbank.com/bio_entities/BE0004926TargetCaenorhabditis elegansAlpha subunit of nicotinic acetylcholine receptor (nAChR) (PubMed:15280391, PubMed:15990870, PubMed:20027209).
Polypeptides: Acetylcholine receptor subunit alpha-type unc-63G protein-coupled bile acid receptor 1
go.drugbank.com/bio_entities/BE0005788TargetHumansG protein-coupled receptor for bile acid (PubMed:12419312, PubMed:12524422, PubMed:32698187, PubMed:32747649, PubMed:35858343).
Polypeptides: G protein-coupled bile acid receptor 1Synonyms: G protein-coupled receptor GPCR19, Membrane-type receptor for bile acidsLymphatic vessel endothelial hyaluronic acid receptor 1
go.drugbank.com/bio_entities/BE0010044TargetHumansLigand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding ...
Polypeptides: Lymphatic vessel endothelial hyaluronic acid receptor 1Synonyms: Hyaluronic acid receptorNuclear receptor subfamily 4immunitygroup A member 1
go.drugbank.com/bio_entities/BE0010494TargetHumansOrphan nuclear receptor. Binds the NGFI-B response element (NBRE) 5'-AAAGGTCA-3' (PubMed:18690216, PubMed:8121493, PubMed:9315652).
Polypeptides: Nuclear receptor subfamily 4immunitygroup A member 1Synonyms: Testicular receptor 3, Orphan nuclear receptor HMRTumor necrosis factor receptor superfamily member 18
go.drugbank.com/bio_entities/BE0010519TargetHumansReceptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.
Polypeptides: Tumor necrosis factor receptor superfamily member 18Synonyms: Activation-inducible TNFR family receptor