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Displaying results 1301 - 1310 of 7181 in total
  1. Drug

    Ancrod

    go.drugbank.com/drugs/DB05099
    ApprovedWithdrawn

    and oxygen to portions of the brain, for which phase III trials are currently being conducted. … FDA granted a 'fast-track status' for investigation of ancrod use in patients suffering from acute ischemic stroke, a life threatening condition caused by the blockage of blood vessels supplying blood

  2. Drug

    Pafolacianine

    go.drugbank.com/drugs/DB15413
    ApprovedInvestigational

    It emits fluorescence within a range of 790 nm to 815 nm with a peak emission of 796 nm. … Pafolacianine, or OTL38, is a folate analogue conjugated with a fluorescent dye that absorbs light in the near-infrared (NIR) spectrum [A242572] within a range of 760 nm to 785 nm, with a peak absorption

  3. Drug

    Dioxybenzone

    go.drugbank.com/drugs/DB11221
    ApprovedWithdrawn

    Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. … Dioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays.

  4. Drug

    Glucarpidase

    go.drugbank.com/drugs/DB08898
    ApprovedInvestigational

    In 1983, the gene for carboxypeptidase G2, or glucarpidase, was derived from _Pseudomonas_ sp. strain RS-16 to be cloned into _Escherichia coli_, allowing the enzyme to be produced in sufficient quantities … from _Pseudomonas stutzeri_ in 1967.

  5. Drug

    Thiosulfuric acid

    go.drugbank.com/drugs/DB09499
    ApprovedInvestigational

    Sodium thiosulfate is also used to reduce the risk of ototoxicity associated with [cisplatin]. … [L43337] When administered 6 hours after cisplatin chemotherapy, Sodium thiosulfate leads to a lower incidence of cisplatin-induced hearing loss among children without affecting its effectiveness.

  6. Drug

    Axicabtagene ciloleucel

    go.drugbank.com/drugs/DB13915
    ApprovedInvestigational

    [A216163] Once T-cells are collected from the patient, they are genetically engineered to express anti-CD19 CARs that recognize and kill cancer cells, and are infused back into the patient. … [L40054] The development of resulted from early preclinical studies conducted by a group of researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 CAR

    Categories: Genetically-modified Autologous T CellsSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptor
  7. Drug

    Chromium

    go.drugbank.com/drugs/DB11136
    ApprovedInvestigational

    Humans can be exposed to chromium via ingestion, inhalation, and dermal or ocular exposure [L1983]. … Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table.

    Mixtures: ADDAMEL N, Advanced B & T Formula
  8. Target

    Nucleotide triphosphate diphosphatase NUDT15

    go.drugbank.com/bio_entities/BE0009809
    EnzymeHumans

    Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:22556419 … Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low.

    Synonyms: Nucleoside diphosphate-linked to another moiety X hydrolase 15
  9. Indication

    Burns first degree

    go.drugbank.com/conditions/DBCOND0015343
    Drugs: Centella asiatica · Nepidermin · Pheniramine · St. John's Wort · Zinc oxide
    Synonyms: Erythema due to burn (first degree), unspecified site
  10. Indication

    Cognitive Dysfunctions

    go.drugbank.com/conditions/DBCOND0063316
    Drugs: Choline alfoscerate · Ginkgo biloba · Piracetam · Pyritinol
    Synonyms: Mild neurocognitive disorder due to known physiological condition