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T cell receptor beta constant 1
go.drugbank.com/bio_entities/BE0003779TargetHumansConstant region of T cell receptor (TR) beta chain (PubMed:24600447).
Polypeptides: T cell receptor beta constant 1Cation-dependent mannose-6-phosphate receptor
go.drugbank.com/bio_entities/BE0004494TargetTransporterHumansLysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal
Polypeptides: Cation-dependent mannose-6-phosphate receptorSynonyms: CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptorReceptor tyrosine-protein kinase erbB-4
go.drugbank.com/bio_entities/BE0004772TargetHumansActs as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. … Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors.
Polypeptides: Receptor tyrosine-protein kinase erbB-4Synonyms: Tyrosine kinase-type cell surface receptor HER4Membrane-associated progesterone receptor component 1
go.drugbank.com/bio_entities/BE0004896TargetHumansForms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization (PubMed:30443021)
Polypeptides: Membrane-associated progesterone receptor component 1GABA(A) Receptor Benzodiazepine Binding Site
go.drugbank.com/bio_entities/BE0008668TargetHumansGABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response (By similarity). … GABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response in a gamma-2 subunit-controlled manner (By similarity)
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Taste receptor type 2 member 16
go.drugbank.com/bio_entities/BE0009016TargetHumansGustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
Polypeptides: Taste receptor type 2 member 16Function: bitter taste receptor activityBone morphogenetic protein receptor type-1A
go.drugbank.com/bio_entities/BE0009272TargetHumansOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. … Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Polypeptides: Bone morphogenetic protein receptor type-1ASynonyms: BMP type-1A receptor, Activin receptor-like kinase 3Bone morphogenetic protein receptor type-2
go.drugbank.com/bio_entities/BE0009324TargetHumansOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
Polypeptides: Bone morphogenetic protein receptor type-2Synonyms: BMP type II receptor, BMP type-2 receptorBone morphogenetic protein receptor type-1B
go.drugbank.com/bio_entities/BE0009415TargetHumansReceptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction … On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
Polypeptides: Bone morphogenetic protein receptor type-1BSynonyms: BMP type-1B receptorInterleukin-1 receptor-associated kinase 1
go.drugbank.com/bio_entities/BE0009452TargetHumansInvolved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation.
Polypeptides: Interleukin-1 receptor-associated kinase 1