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Displaying results 1331 - 1340 of 10000 in total
  1. Drug

    Valerian

    go.drugbank.com/drugs/DB13196
    Approved

    Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. … [DB00313] is a derivative of valeric acid, which is obtained from the plant root.

    Mixtures: S. R. Formula, Lapidar 7 TabProducts: Sleep-eze V Natural Caplets
  2. Drug

    Silicon dioxide

    go.drugbank.com/drugs/DB11132
    Approved

    Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer. … It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals.

    Mixtures: DOCTRUST ONE S Tooth, DOCTRUST ONE S ToothCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Rocaglamide

    go.drugbank.com/drugs/DB15495
    Experimental

    Rocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides. … [A186796] Reports of _Aglaia_ anti-tumor activity date back as far as 1973, and rocaglamide-A was first isolated in 1982 from the species _A. elliptifolia_.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Prednisolone acetate

    go.drugbank.com/drugs/DB15566
    ApprovedInvestigationalVet approved

    Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]

    Mixtures: CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERIL, PREFOX-T®Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  5. Drug

    Didesmethylrocaglamide

    go.drugbank.com/drugs/DB15496
    Experimental

    Didesmethylrocaglamide is a naturally-occurring derivative of [rocaglamide] and belongs to a class of anti-cancer phytochemicals referred to as "rocaglamides" derived from plants of the genus _Aglaia_. … [A186760] While traditionally used for their insecticidal benefits,[A186796] this class of compounds is now being studied for use as chemotherapeutic agents in the treatment of various leukemias, lymphomas

  6. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte S
  7. Drug

    Noscapine

    go.drugbank.com/drugs/DB06174
    Approved

    Mixtures: TONIN COUGH SYRUP S, NEUMOLEX® NFCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2C9 Inhibitors
  8. Drug

    Dicyclomine

    go.drugbank.com/drugs/DB00804
    ApprovedInvestigational

    [A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable. … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder

    Mixtures: AXCEL DICYCLOMINE-S SYRUPSynonyms: 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate, Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester
  9. Target

    Mitogen-activated protein kinase kinase kinase kinase 1

    go.drugbank.com/bio_entities/BE0009470
    TargetHumans

    Serine/threonine-protein kinase, which plays a role in the response to environmental stress (PubMed:24362026). Appears to act upstream of the JUN N-terminal pathway (PubMed:8824585). Activator of the Hippo signaling pathway which plays a...

    Synonyms: MEK kinase kinase 1
  10. Drug

    Sorbitol

    go.drugbank.com/drugs/DB01638
    ApprovedInvestigational

    It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. … A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose.

    Synonyms: G-ol, D-SorbitMixtures: MINICA S ENEMA, Cystosol W 3% Hexitols