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Displaying results 1351 - 1360 of 9667 in total
  1. Target

    Serine/threonine-protein kinase PAK 5

    go.drugbank.com/bio_entities/BE0009510
    TargetHumans

    Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor rec...

    Polypeptides: Serine/threonine-protein kinase PAK 5Synonyms: PAK-5, PAK-7
  2. Target

    Serine/threonine-protein kinase PAK 2

    go.drugbank.com/bio_entities/BE0009506
    TargetHumans

    On the other hand, apoptotic stimuli such as DNA damage lead to caspase-mediated cleavage of PAK2, generating PAK-2p34, an active p34 fragment that translocates to the nucleus and promotes cellular apoptosis

    Polypeptides: Serine/threonine-protein kinase PAK 2Synonyms: PAK-2, Gamma-PAK
  3. Target

    Serine/threonine-protein kinase PAK 3

    go.drugbank.com/bio_entities/BE0009507
    TargetHumans

    Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse f...

    Polypeptides: Serine/threonine-protein kinase PAK 3Synonyms: PAK-3, Beta-PAK
  4. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    It is a major metabolic intermediate in most organisms. … Allantoin has also demonstrated to ameliorate the wound healing process in some studies [A23498].

    Mixtures: Actinac Pws, Mycellcare iT sProducts: Dr Young 2p Blemish Base SPF35 PA, Young 2P Pearl Brightening Balm SPF35 PA
  5. Drug

    Ethinamate

    go.drugbank.com/drugs/DB01031
    ApprovedIllicitWithdrawn

    Structurally, it does not resemble the barbituates, but it shares many effects with this class of drugs; the depressant effects of ethinamate are, however, generally milder than those of most barbiturates … Nevertheless, the medication itself is generally no longer effective after using it for greater than 7 days.

  6. Drug

    Vorapaxar

    go.drugbank.com/drugs/DB09030
    Approved

    of myocardial infarction (MI) or with peripheral arterial disease (PAD). … By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.

    Categories: Receptor, PAR-1, antagonists & inhibitorsSynonyms: [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto[2,3-c]furan-6-yl]carbamate d'éthyle, Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester
  7. Target

    Serine/threonine-protein kinase PAK 4

    go.drugbank.com/bio_entities/BE0009508
    TargetHumans

    Serine/threonine-protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell adhesion turnover, cell migration, growth, proliferation or cell survival (PubMed:26598620). Activatio...

    Polypeptides: Serine/threonine-protein kinase PAK 4Synonyms: PAK-4
  8. Drug

    Pipemidic acid

    go.drugbank.com/drugs/DB13823
    Investigational

    Pipemidic acid is a quinolone antibacterial agent with activity against various gram-positive and gram-negative bacteria.

    Products: ACIDO PIPEMIDICO EG
  9. Drug

    Entacapone

    go.drugbank.com/drugs/DB00494
    ApprovedInvestigational

    It is a member of the class of nitrocatechols. … When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration

    Mixtures: DOPALEVO 100MG/25MG/200MG FILM KAPLI TABLET ,100TABLET, STALEVO 200MG/50MG/200MGSynonyms: (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide
  10. Drug

    Flumethasone

    go.drugbank.com/drugs/DB00663
    ApprovedVet approved

    As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application.

    Mixtures: LOCASALENE 0,2MG/G+30MG/G MERHEM, 30 G, PMS-flumethasone-clioquinol